scholarly journals Serum carotenoid and retinol levels in African-Caribbean Tobagonian men with high prostate cancer risk in comparison with African-American men

2017 ◽  
Vol 117 (8) ◽  
pp. 1128-1136 ◽  
Author(s):  
Alicia C. McDonald ◽  
Clareann H. Bunker ◽  
Jay Raman ◽  
John Richie ◽  
Alan L. Patrick
Keyword(s):  
Prostate Cancer ◽  
African American ◽  
African American Men ◽  
Specific Antigen ◽  
Elevated Serum ◽  
Prostate Cancer Risk ◽  
Serum Retinol ◽  
Populations At Risk ◽  
African Caribbean ◽  
Black Populations

AbstractBlack men are known to have a higher risk for prostate cancer (PC). Carotenoids and retinol, linked to PC, have not been compared in different black populations at risk. We examined serum carotenoid and retinol levels between PC-free African-Caribbean (AC) Tobagonian men with a high PC risk (high-grade prostatic intraepithelial neoplasia, atypical foci or repeated abnormal PC screenings) and African-American (AA) men with elevated serum prostate-specific antigen (PSA) levels (≥4 ng/ml). AC men who participated in the 2003 lycopene clinical trial and AA men who participated in the 2001–2006 National Health and Nutrition Examination Survey were compared. Serum specimens were analysed for carotenoid (β-carotene, α-carotene, β-cryptoxanthin, lutein/zeaxanthin and lycopene) and retinol levels by isocratic HPLC. Quantile regression was used to examine the association between serum carotenoid and retinol levels and black ethnicity, overall and among men with elevated serum PSA. There were sixty-nine AC men and sixty-five AA men, aged 41–79 years, included. AC men were associated with lower serum lycopene and retinol levels, and higher serum α- and β-carotenes and lutein/zeaxanthin levels compared with AA men, after adjusting for age, BMI, ever smoked cigarettes, education and hypertension (P≤0·03). Among men with elevated PSA, serum retinol was no longer statistically significant with ethnicity (P=0·06). Possible differences may be attributed to dietary intake, genetics and/or factors that influence bioavailability of these micronutrients. Prospective studies are warranted that investigate whether these differences in micronutrients between AC Tobagonian and AA men influence PC risk.

scholarly journals Prostate Cancer Ambassadors

2016 ◽  
Vol 11 (1) ◽  
pp. 54-62 ◽  
Author(s):  
Anissa I. Vines ◽  
Jaimie C. Hunter ◽  
Veronica A. Carlisle ◽  
Alan N. Richmond
Keyword(s):  
Prostate Cancer ◽  
African American ◽  
Collective Efficacy ◽  
African American Men ◽  
Prostate Cancer Screening ◽  
Specific Antigen ◽  
Prostate Cancer Risk ◽  
Informed Decision ◽  
Cancer Information ◽  
Cancer Knowledge

African American men bear a higher burden of prostate cancer than Caucasian men, but knowledge about how to make an informed decision about prostate cancer screening is limited. A lay health advisor model was used to train “Prostate Cancer Ambassadors” on prostate cancer risk and symptoms, how to make an informed decision for prostate-specific antigen screening, and how to deliver the information to members of their community. Training consisted of two, 6-hour interactive sessions and was implemented in three predominantly African American communities over an 8-month period between 2013 and 2014. Following training, Ambassadors committed to contacting at least 10 people within 3 months using a toolkit composed of wallet-sized informational cards for distribution, a slide presentation, and a flip chart. Thirty-two Ambassadors were trained, with more than half being females (59%) and half reporting a family history of prostate cancer. Prostate cancer knowledge improved significantly among Ambassadors ( p ≤ .0001). Self-efficacy improved significantly for performing outreach tasks ( p < .0001), and among women in helping a loved one with making an informed decision ( p = .005). There was also an improvement in collective efficacy in team members ( p = .0003). Twenty-nine of the Ambassadors fulfilled their commitment to reach at least 10 people (average number of contacts per Ambassador was 11). In total, 355 individuals were reached with the prostate cancer information. The Ambassador training program proved successful in training Ambassadors to reach communities about prostate cancer and how to make an informed decision about screening.

PD10-05 UNDERESTIMATION OF PROSTATE CANCER RISK AT DIAGNOSIS AMONG AFRICAN AMERICAN MEN

2017 ◽  
Vol 197 (4S) ◽  
Author(s):  
Nathan Peffer ◽  
Daniel Parker ◽  
Laura Giusto ◽  
Joshua Jones ◽  
Anastasia Kamenko ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
African American ◽  
Cancer Risk ◽  
African American Men ◽  
Prostate Cancer Risk

Religious Involvement and Prostate Cancer Screening Behaviors Among Southeastern African American Men

2008 ◽  
Vol 3 (3) ◽  
pp. 214-223 ◽  
Author(s):  
Cheryl L. Holt ◽  
Theresa A. Wynn ◽  
Jasmine Darrington
Keyword(s):  
Prostate Cancer ◽  
African American ◽  
Cancer Screening ◽  
African American Men ◽  
Prostate Cancer Screening ◽  
Specific Antigen ◽  
Digital Rectal Examination ◽  
Religious Involvement ◽  
Educational Interventions ◽  
Religious Behaviors

This study examined the relationship between religious involvement and prostate cancer screening behavior among a probability sample of 199 African American men. Religious involvement was assessed by telephone via a multidimensional instrument. Engaging in religious behaviors was predictive of reporting a digital rectal examination (DRE) within the past year. Religious beliefs and behaviors were predictive of behavioral intention for DRE in the next 6 months. Religious behaviors were predictive of reporting an appointment for a DRE in the next 6 months. All analyses were controlled for age, education, and marital status. None of the predictions were significant for prostate-specific antigen testing. Understanding the role of religious involvement in cancer beliefs and screening is important. Such knowledge can inform educational interventions for this group, which is disproportionately affected by prostate cancer.

scholarly journals Correlating blood-based DNA methylation markers and prostate cancer risk in African-American men

PLoS ONE ◽  
2018 ◽  
Vol 13 (9) ◽  
pp. e0203322 ◽  
Author(s):  
Emmanuel Moses-Fynn ◽  
Wei Tang ◽  
Desta Beyene ◽  
Victor Apprey ◽  
Robert Copeland ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Dna Methylation ◽  
African American ◽  
Cancer Risk ◽  
African American Men ◽  
Prostate Cancer Risk

ELEVATED SERUM LOW DENSITY LIPOPROTEIN (LDL) IS ASSOCIATED WITH AN INCREASED RISK OF PROSTATE CANCER IN AFRICAN-AMERICAN MEN

2008 ◽  
Vol 179 (4S) ◽  
pp. 150-150
Author(s):  
Kelvin A Moses ◽  
Thura T Abd ◽  
John A Hall ◽  
Michael Goodman ◽  
Muta M Issa ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
African American ◽  
African American Men ◽  
Low Density Lipoprotein ◽  
Elevated Serum ◽  
Density Lipoprotein ◽  
Low Density ◽  
Increased Risk

605 COMBINATION OF ADH GENE POLYMORPHISM AND ALCOHOL CONSUMPTION CONSTITUTES A NOVEL PROSTATE CANCER RISK FACTOR IN AFRICAN-AMERICAN MEN

2011 ◽  
Vol 185 (4S) ◽  
Author(s):  
Lionel L. Bañez ◽  
Cathrine Hoyo ◽  
Elizabeth M. Masko ◽  
Elizabeth E. Calloway ◽  
Kathleen H. Shuler ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
African American ◽  
Risk Factor ◽  
Alcohol Consumption ◽  
Cancer Risk ◽  
Gene Polymorphism ◽  
African American Men ◽  
Prostate Cancer Risk ◽  
Cancer Risk Factor ◽  
Adh Gene

Abstract B18: Interactions between finasteride and vitamin D-related polymorphisms is associated with prostate cancer risk in African American men

2015 ◽  
Author(s):  
Kathleen C. Torkko ◽  
Cathee Till ◽  
Phyllis J. Goodman ◽  
Catherine M. Tangen ◽  
Adrie van Bokhoven ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Vitamin D ◽  
African American ◽  
Cancer Risk ◽  
African American Men ◽  
Prostate Cancer Risk
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