Changes in the concentration of plasma proteins in intensively bred ewes

1977 ◽  
Vol 88 (2) ◽  
pp. 283-288 ◽  
Author(s):  
W. S. Mackie

SUMMARYThe mean concentration of plasma albumin in 30 Finnish Landrace x Dorset Horn ewes subjected to intensive breeding decreased as the number of pregnancies increased from three to seven; it also changed significantly within a pregnancy. Gamma globulin concentration was not affected by the number of pregnancies but decreased significantly within a pregnancy. Total plasma protein was affected like albumin by the number and stage of pregnancy.Plasma volume increased by 23 % in the latter third of pregnancy.

Author(s):  
Y. S. Pustsyulga ◽  
O. V. Gribovskaya ◽  
E. M. Ermola ◽  
V. P. Golubovich ◽  
A. G. Moiseenok

Biospecific sorbents for the removal of IgG and subclasses from biological fluids based on oligopeptides, containing aromatic amino acid residues, were created. The selectivity properties of specific sorbents for IgM, IgE, and plasma proteins were evaluated. It was found that the created sorbents exhibit the low activity to the total plasma protein, albumin, IgM, IgE and are highly specific for IgG.


1984 ◽  
Vol 12 (01n04) ◽  
pp. 106-114 ◽  
Author(s):  
D.M. Hau

The effects of electroacupunture on leukocytes and plasma protein on X ray-irradiated rats were investigated in the present study. The results showed that X-irradiation had an evident inhibitory effect on the counts of total leukocytes, lymphocytes and neutrocytes, and the concentration of the total plasma protein, plasma albumin, globulin and α- and β-globulin in X-irradiated rats. The electroacupuncture was able to help the X-irradiated rats to recover the counts of the total leukocyte, lymphocyte and neutrocyte. The electroacupuncture had a helpful tendency to recover the concentration of the total plasma protein, albumin, globulin, and α- and β-globulin in the irradiated rats.


1961 ◽  
Vol 200 (1) ◽  
pp. 152-154 ◽  
Author(s):  
L. L. Sulya ◽  
B. E. Box ◽  
Gordon Gunter

The plasma proteins of 14 families and 26 species of fishes from Gulf coast marine waters have been studied electrophoretically. Analbuminemia has been observed not only in elasmobranchs, but in gars and some clupeids, as well as in two species of higher fishes. Analbuminemia is characteristic of the lower fishes and gradually disappears as fishes become more complex, but not entirely, since the condition exists in a few higher fishes. In addition, several species were lacking in the alpha-1-globulin fraction. There is an increase in complexity of plasma proteins from lower to higher fishes. The plasma proteins show specific differences and may be quite different in closely related fishes. The total plasma protein is lower than in mammals.


1967 ◽  
Vol 37 (3) ◽  
pp. 261-268 ◽  
Author(s):  
J. Y. F. PATERSON ◽  
F. HILLS

SUMMARY Albumin was isolated from ovine plasma and its affinity for cortisol was determined by equilibrium dialysis at 37°. The value of Ka[σpa] for a 1 % (w/v) albumin solution was 0·275 which is similar to the value for human plasma albumin. The affinity constant of transcortin in ovine plasma was determined by equilibrium dialysis of diluted plasma at several concentrations of cortisol. The value found, Kt (37°) = 0·87 x 108 l./mole, is close to that found for human plasma transcortin by Mills (1962). The concentration of transcortin in ovine plasma, expressed as cortisolbinding capacity, was 6–49 μg. (mean 24 μg.) cortisol/l. These concentrations are much lower than those found in human plasma. The observation of Lindner (1964) that cortisol binding capacity did not increase during pregnancy in sheep has been confirmed. In sheep which were accustomed to handling, the mean concentration of cortisol in plasma was 17·8 μg./l. and of this amount 59% was bound to transcortin, 19 % to albumin and 22 % was not bound to protein.


1997 ◽  
Vol 77 (2) ◽  
pp. 255-271 ◽  
Author(s):  
A. Connell ◽  
A. G Calder ◽  
S. E Anderson ◽  
G. E Lobley*

Rates of protein synthesis for the liver, plasma albumin and total plasma protein were quantified in sheep either offered a supra-maintenance intake or fasted for 3 d. The technique of continuous infusion over a 12 h period was employed with the simultaneous infusion of [1-13C]glycine, [1-13C]leucine and [2H5]phenylalanine. Blood and plasma samples were removed at timed intervals from the hepatic portal and hepatic veins plus the aorta. Enrichments of the free amino acids (AA) were determined in all blood and plasma samples as was the protein-bound AA in an apolipoprotein B100 extract. Protein-bound phenylalanine enrichments were also measured in albumin and total protein from plasma plus samples from liver biopsies. The apolipoprotein B100 enrichments agreed well with those of the free AA in hepatic (and hepatic portal) plasma but were lower than for arterial free AA and greater than liver homogenate free AA. This adds support to the concept that export proteins may preferentially use AA directly from extracellular sources. Intake had no significant effect on constitutive liver protein synthesis and the values agreed well with those obtained by other isotopic approaches. There were, however, signicant declines, based on hepatic venous free phenylalanine enrichment, at the lower intake in both the fractional (3·4v. 4·7 % per d;P=0·024) and absolute (2·4v. 4·2 g/d;P=0·011) synthesis rates of albumin, which matched the estimated decrease in total plasma albumin content (52v. 67 g,P<0·01). In contrast, there was a smaller reduction in total plasma protein mass (145v. 151 g,P=0·035) with no observed significant difference in kinetic parameters. Albumin synthesis was calculated to account for a maximum of 17 % of total liver protein synthesis in the fed condition and this may fall to 8 % during moderate fasts.


1957 ◽  
Vol 35 (2) ◽  
pp. 283-289 ◽  
Author(s):  
P. J. Bandy ◽  
W. D. Kitts ◽  
A. J. Wood ◽  
I. McT. Cowan

The blood sugar, non-protein nitrogen, total plasma protein, plasma albumin, globulin, and fibrinogen of the Columbian black-tailed deer have been studied on two series of animals reared on high and low planes of nutrition from birth to 465 days of age. Of these blood constituents only blood sugar and fibrinogen showed a measurable lowering in the low plane animals. Age changes have been noted that are independent of nutritive state but are similar to those reported for domestic ruminants.


2000 ◽  
Vol 88 (3) ◽  
pp. 1006-1013 ◽  
Author(s):  
Michael I. Lindinger ◽  
L. J. McCutcheon ◽  
G. L. Ecker ◽  
R. J. Geor

This study determined the plasma volume (PV) and ion responses to heat acclimation and exercise in six trained Thoroughbred horses during 21 days of exposure to heat and humidity (33°C, 83% relative humidity) for 4 h/day. During the 2nd h on days 0, 3, 7, 14, and 21, horses performed a standardized treadmill test, running at 50% of peak O2uptake until pulmonary artery temperature reached 41.5°C. Heat acclimation resulted in an increase in PV from 21.3 ± 1.1 liters on day 0 to 24.3 ± 1.0 liters on day 14, returning to 22.6 ± 0.9 liters on day 21. The corresponding total plasma protein contents were 1,273 ± 53, 1,455 ± 81, and 1,377 ± 57 g, respectively, and increases in total plasma Na+ plus Cl− content were 5,145 ± 126, 5,749 ± 146, and 5,394 ± 114 mmol, respectively. Thus changes in PV were accompanied by direct changes in plasma protein and osmolyte contents. With exercise on day 0, PV decreased by 7.1 ± 0.7% at 5 min of exercise and remained decreased (−6.7 ± 1.3%) at 5 min of recovery. By day 21, PV decreased significantly less than on day 0 (by 5.2 ± 0.9% at 5 min of exercise), was decreased by only 2.0 ± 1.6% at 5 min of recovery, and was fully restored at 15 min of recovery. Plasma Na+ concentration increased 3 meq/l during the first 5 min of exercise and was normalized by 5 min of recovery on day 0 and by end exercise on day 21. It is concluded that improved ability to regulate PV during exercise in response to heat acclimatization is associated with an increased PV and an improved conservation of Na+.


1969 ◽  
Vol 73 (2) ◽  
pp. 203-209 ◽  
Author(s):  
J. E. Vercoe ◽  
P. H. Springell

SUMMARYThe differential effect of subclinical helminthosis on digestion and nitrogen metabolism in 1-year-old Brahman x Hereford/Shorthorn cross and British (Hereford/Shorthorn cross) steers was investigated.When helminths were present, the British steers had lower digestibilities of dry matter and nitrogen, lower nitrogen balances, and higher dialysable faecal nitrogen, than had the Brahman cross steers. There were no breed differences in plasma gastrointestinal leakage (estimated by Cr labelling of plasma proteins), plasma content, total plasma protein, plasma protein half-life or plasma urea.When helminths were eliminated, plasma gastrointestinal leakage was reduced, and plasma content and total plasma protein were increased. These changes were relatively larger in the British steers. The Brahman crosses had lower plasma protein concentrations and higher plasma urea concentrations than the British steers. Plasma protein half-life was unaffected by parasites.The breed difference in the haematocrit was not affected by the presence or absence of helminths.


1957 ◽  
Vol 5 (3) ◽  
pp. 257-260 ◽  
Author(s):  
REX J. UNDERWOOD ◽  
HERBERT E. GRISWOLD ◽  
WILLIAM A. HURST

1924 ◽  
Vol 39 (6) ◽  
pp. 921-929 ◽  
Author(s):  
G. C. Linder ◽  
C. Lundsgaard ◽  
D. D. Van Slyke ◽  
E. Stillman

1. We have not observed gross increases in plasma volume in glomerulonephritis, nephrosis, or nephrosclerosis, even when the concentration of plasma proteins was much below normal. Our results indicate the probability that "hydremic plethora" does not occur. 2. The low protein concentration frequently observed in the plasma in nephritis is not due to increased plasma volume but to a decrease of the total amount of plasma protein in the body. 3. Changes in plasma volume showed no constant relationship to changes in edema.


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