Kimura's disease: case report and brief review of the literature

1994 ◽  
Vol 108 (11) ◽  
pp. 1005-1007 ◽  
Author(s):  
Mette Nyrop

AbstractKimura's disease is a chronic inflammatory disease which often presents as a tumour-like swelling in the head and neck region with or without lymphadenopathy. Most cases have been described predominantly in Chinese and Japanese people. The lesion is benign, but it may easily be mistaken for a malignant tumour. Kimura's disease has been confused with angiolymphoid hyperplasia with eosinophilia (ALHE), from which it probably should be distinguished as a separate entity. The diagnosis may be suggested by a fine needle aspirate, but is established by a biopsy. The treatment of choice is surgical removal.A case of Kimura's disease in a Caucasian male of 12 years' duration is presented together with a brief review of the literature.

2020 ◽  
Vol 6 (4) ◽  
pp. 20200099
Author(s):  
Célia Peixoto Sousa ◽  
Elsa Fonseca ◽  
Bárbara Viamonte ◽  
João Calheiros Lobo ◽  
António Madureira

Kimura’s disease is an uncommon inflammatory disorder of unclear aetiology, mainly affecting young Asian descent males among their second and fourth decades of life. The disease typically emerges as a long-standing and painless subcutaneous mass lesion in the head and neck region, frequently associated with swelling of major salivary glands, particularly the parotid gland, and regional lymphadenopathy. Peripheral eosinophilia and high serum immunoglobulin E are also characteristic findings. We report a case and describe the imaging and pathological features of the disease in a 19-year-old Caucasian male, with review of the literature.


1996 ◽  
Vol 110 (11) ◽  
pp. 1084-1087 ◽  
Author(s):  
Nalinikanth Pamaraju ◽  
S. A. Khalifa ◽  
Abdulla Darwish ◽  
K. O. Paulose ◽  
Nissar Ahmed ◽  
...  

AbstractKimura's disease is a rare condition of unknown aetiology. It usually presents as a mass in the head and neck region. The diagnosis is confirmed by biopsy and usually treated by excision even though recurrence is common. This condition can be mistaken for a malignant tumour. In this case report Kimura's disease presented as a nonspecific lymphadenitis in an Arab patient.


Author(s):  
Aarti S. Salunke ◽  
Ravindranath B. Chavan ◽  
Vasudha A. Belgaumkar ◽  
Neelam Bhatt

<p style="margin-bottom: 0in; line-height: 100%;" align="JUSTIFY">Kimura’s disease is a rare chronic inflammatory disease of unknown etiology, presenting as painless subcutaneous nodules with lymphadenopathy and peripheral eosinophilia, mainly disturbing the head and neck region. It mainly affects Asian males in their 2nd to 4th decade of life. Kimura’s disease, although difficult to diagnose clinically, should be considered in the differential diagnosis of patients who have a primary lymphadenopathy with eosinophilia with or without subcutaneous nodules. It should be investigated accordingly as the disease has an indolent course and good prognosis. Herein we report two cases of Kimura’s disease, of which one had unusual site of involvement. </p>


2018 ◽  
Vol 3 (8) ◽  

Kimura’s disease is a rare chronic inflammatory disease of uncertain cause, manifesting commonly as a painless swelling of the subcutaneous tissue in the head and neck region with predilection for peri auricular areas. A significant increase in serum levels of immunoglobulin E and eosinophilia in the peripheral blood and in tissues has been associated with this disorder. Many cases of nephropathy in patients with Kimura’s Disease had been reported in the literature. Excisional biopsy for histopathological evaluation is the only way to confirm the diagnosis of Kimura’s Disease. We report a case of Kimura’s disease in a 26-year- old female patient who presented to our clinic with painless right retro-auricular swellings.


Author(s):  
Vinay Bharat ◽  
Abhishek Gupta ◽  
Rani Bansal ◽  
Priya Gupta ◽  
Mamta Gupta

Kimura’s disease is a rare chronic inflammatory disorder present in 2nd and 3rd decade. It has a predilection for head and neck region presenting as a slowly growing painless swelling. It is usually accompanied by peripheral eosinophilia and elevated serum IgE and hence it was initially thought to be of allergic origin. Histologically the lesions are characterized by reactive hyperplasia of lymph nodes, eosinophilic infiltration and increase in postcapillary venules. Authors have reported a male patient with a slowly growing right sided neck swelling which is recurring even after course of steroids and excision done twice at an interval of 6 months. Kimura’s disease although a benign Lymphoid disorder but the incidence of recurrence despite taking treatment is a cause of much concern for the patient.


1998 ◽  
Vol 112 (2) ◽  
pp. 166-168 ◽  
Author(s):  
R. Murat Karasen ◽  
Yavuz Sutbeyaz ◽  
Cemal Gundogdu ◽  
Bulent Aktan

AbstractLeiomyosarcoma is a malignant tumour of smooth muscle origin. These tumours are rarely encountered in the head and neck region. A case of leiomyosarcoma of the auricle is presented. There are two cases of external auditory canal leiomyosarcoma in the literature. To our knowledge the present case is the first example of leiomyosarcoma of the auricle.


2021 ◽  
Vol 14 (1) ◽  
pp. e232627
Author(s):  
Jacqueline Ho ◽  
Sophie Walter ◽  
Richard J Harvey

Kimura’s disease is a rare, benign, chronic inflammatory disorder characterised by its eosinophilic infiltrate. Patients often present with one or more progressively enlarging subcutaneous lymph nodes in the head and neck region or enlarging salivary glands. We describe the case of a 26-year-old man presenting with severe peripheral eosinophilia and upper airway inflammatory symptoms, who later developed cervical lymphadenopathy and formally diagnosed with Kimura’s disease. Based on our English-language MEDLINE literature search, to our knowledge this is the first case report describing treatment of Kimura’s disease with mepolizumab.


2020 ◽  
Vol 99 ◽  
pp. 1-12 ◽  
Author(s):  
Martina Baněčková ◽  
Petr Martínek ◽  
Alena Skálová ◽  
Roman Mezencev ◽  
Ladislav Hadravský ◽  
...  

2018 ◽  
Vol 7 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Pai Pang ◽  
Weiyi Duan ◽  
Shuchun Liu ◽  
Shuang Bai ◽  
Yanan Ma ◽  
...  

1990 ◽  
Vol 104 (12) ◽  
pp. 977-979 ◽  
Author(s):  
J. F. Sharp ◽  
M. J. C. Rodgers ◽  
F. B. Macgregor ◽  
C. J. Meehan ◽  
K. McLaren

AbstractAngiolymphoid hyperplasia with eosinophilia is a rare condition and is poorly recognized in the otolaryngological literature. The condition is characterized by the appearance of cutaneous nodules within the head and neck region especially around the external ear. Variable lymphadenopathy and peripheral eosinophilia can occur and the condition can mimic neoplasia. It is important to be aware of this disease entity in order to avoid overtreatment. Surgical removal is the treatment of choice; however, this often multilobulated and poorly delineated lesion often precludes initial wide excision and local recurrence is common.We present three cases of this unusual condition and a brief resumé of the literature.


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