Malignant fibrous histiocytoma of the floor of the mouth: case report

AbstractMalignant fibrous histiocytoma (MFH) is a common neoplasm of soft tissue. The floor of the mouth is an unusual site of origin and has not been described in the literature previously. Its rarity, aspecific clinical symptoms and complex histopathology combine to make the diagnosis difficult. The treatment of choice is wide surgical excision with adjunctive irradiation.

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Primary Malignant Fibrous Histiocytoma of the Lung: A Case Report

Case Reports in Medicine ◽

10.1155/2010/389692 ◽

2010 ◽

Vol 2010 ◽

pp. 1-4 ◽

Cited By ~ 3

Author(s):

I. Tsangaridou ◽

G. Papamihalis ◽

K. Stathopoulos ◽

O. Konstantinopoulos ◽

L. Thanos

Keyword(s):

Radiation Therapy ◽

Case Report ◽

Soft Tissue ◽

Surgical Resection ◽

Malignant Fibrous Histiocytoma ◽

Fibrous Histiocytoma ◽

Soft Tissue Sarcomas ◽

Distant Recurrence ◽

Local Relapse ◽

Metastatic Lesions

Primary malignant fibrous histiocytoma (MFH) of the lung is extremely rare although it is among the most common soft tissue sarcomas in adults. Surgery is the primary mode of therapy, with high rates of local and distant recurrence, while radiation therapy appears to be a very useful adjunct, decreasing local relapse. We report a case of primary malignant fibrous histiocytoma of the lung. Fourteen years after surgical resection, the patient is still alive although with multiple metastatic lesions throughout his body.

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Chest Wall Reconstruction : A Case Report

Bangladesh Journal of Plastic Surgery ◽

10.3329/bdjps.v3i2.18252 ◽

2014 ◽

Vol 3 (2) ◽

pp. 53-56

Author(s):

Md Zakir Hossain ◽

Shamim Hassan ◽

Ayesha Hanna ◽

Md Shahin

Keyword(s):

Quality Of Life ◽

Case Report ◽

Soft Tissue ◽

Plastic Surgery ◽

Chest Wall ◽

Soft Tissue Tumor ◽

Surgical Excision ◽

Wide Surgical Excision ◽

Tissue Tumor

We are reporting a case of recurrent soft tissue tumor over the chest wall-histologically proven Dermato fibrosarcoma protuberance. Wide surgical excision with reconstruction is recommended for improvement of quality of life and prolong survival. DOI: http://dx.doi.org/10.3329/bdjps.v3i2.18252 Bangladesh Journal of Plastic Surgery July 2012, 3(2): 53-56

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Primary Pulmonary Malignant Fibrous Histiocytoma

Case Reports in Pulmonology ◽

10.1155/2015/381276 ◽

2015 ◽

Vol 2015 ◽

pp. 1-5

Author(s):

Devin P. Patel ◽

Yogesh S. Gandhi ◽

Keith E. Sommers ◽

Devanand Mangar ◽

Enrico M. Camporesi

Keyword(s):

Soft Tissue ◽

Malignant Fibrous Histiocytoma ◽

Primary Tumor ◽

Rare Case ◽

Diagnostic Procedure ◽

Fibrous Histiocytoma ◽

Soft Tissue Sarcomas ◽

Surgical Excision

Malignant fibrous histiocytoma (MFH) is one of the most common adult soft tissue sarcomas. MFH is very aggressive and is most often found in the extremities and the retroperitoneum, but it can manifest at other sites. Though the lungs are the most common sites of metastasis, they rarely present there as a primary tumor. Our report describes a rare case of a primary MFH tumor in the lung. Careful diagnostic procedure should be followed to ensure the tumor does not have extrapulmonary origins. Though MFH is highly invasive and deadly, surgical excision of the tumor has been shown to be successful.

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Tc-99m-methylene diphosphonate (Tc-99m MDP) and Ga-67 concentration in soft tissue malignant fibrous histiocytoma (MFH): Case report

Annals of Nuclear Medicine ◽

10.1007/bf03164794 ◽

1993 ◽

Vol 7 (1) ◽

pp. 57-60

Author(s):

Toshiyuki Kida ◽

Koji Hoshi ◽

Ryouichi Hoshino ◽

Yuji Fujita ◽

Shiro Munakata ◽

...

Keyword(s):

Case Report ◽

Soft Tissue ◽

Malignant Fibrous Histiocytoma ◽

Fibrous Histiocytoma ◽

Methylene Diphosphonate

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The Ultrastructure of Malignant Fibrous Histiocytoma (Case Report)

Tumori Journal ◽

10.1177/030089167706300411 ◽

1977 ◽

Vol 63 (4) ◽

pp. 387-396 ◽

Cited By ~ 5

Author(s):

Luciano Lombardi ◽

Silvana Pilotti ◽

Antonino Carbone ◽

Franco Rilke

Keyword(s):

Electron Microscopy ◽

Stem Cells ◽

Case Report ◽

Soft Tissue ◽

Malignant Fibrous Histiocytoma ◽

Fibrous Histiocytoma ◽

Light And Electron Microscopy ◽

Giant Cells ◽

Multinucleated Giant Cells ◽

Cellular Types

A soft tissue malignant fibrous histiocytoma was studied by light and electron microscopy. The presence of fibroblast-like cells, histiocyte-like cells, undifferentiated stem cells, and xanthomatous cells was confirmed. Fibroblast- and histiocyte-like multinucleated giant cells were also observed. The observation of lysosomes in some fibroblast-like cells, the features of undifferentiated stem cells, and the presence of cells with intermediate characteristics common to xanthomatous, histiocytic, and stem cells suggest a strict relationship among these cellular types.

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Primary giant cell malignant fibrous histiocytoma-associated with renal calculus

Canadian Urological Association Journal ◽

10.5489/cuaj.1485 ◽

2014 ◽

Vol 8 (3-4) ◽

pp. 193 ◽

Cited By ~ 3

Author(s):

Adem Altunkol ◽

Murat Savas ◽

Halil Ciftci ◽

Mehmet Gulum ◽

Ismail Yagmur ◽

...

Keyword(s):

Case Report ◽

Soft Tissue ◽

Giant Cell ◽

Malignant Fibrous Histiocytoma ◽

Fibrous Histiocytoma ◽

Soft Tissue Sarcomas ◽

Renal Calculus ◽

Fibrous Histiocytomas ◽

Malignant Fibrous Histiocytomas ◽

Visceral Organs

Malignant fibrous histiocytomas (MFH) are the most commonly seen soft tissue sarcomas in adults. It is rarely seen in some visceral organs. Kidneys are the parenchymal organs in which MFHs are most frequently seen. More than 50 cases of primary renal MFH have been reported. Among these cases, only 1 was reported as primary giant cell subtype in association with urolithiasis. This case report is the second such case with the these characteristics.

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LOCAL RECURRENCES AFTER THE TREATMENT OF SOFT TISSUE MALIGNANT FIBROUS HISTIOCYTOMA (UNCLASSIFIEDPLEOMORPHIC SARCOMA) OF THE LIMBS

Wiadomości Lekarskie ◽

10.36740/wlek201908120 ◽

2019 ◽

Vol 72 (8) ◽

pp. 1523-1526

Author(s):

Oleksandr O. Lytvynenko ◽

Volodymyr F. Konovalenko ◽

Anton Yu. Ryzhov

Keyword(s):

Soft Tissue ◽

Malignant Fibrous Histiocytoma ◽

Fibrous Histiocytoma ◽

Survival Rates ◽

Soft Tissue Sarcomas ◽

Primary Treatment ◽

Radical Excision ◽

Local Recurrences ◽

Results Of Treatment

Introduction: The treatment of patients with malignant fibrous histiocytoma as well as other soft tissue sarcomas is not sufficiently effective up to date, and has largely changed and reflects the alterations, occurred in oncology as a whole. The number of amputation decreased over the last 10-15 years. Some researchers associate the improvement of treatment outcomes with the development of combined and complex methods. The aim of the study is an improvement of the results of treatment of patients with soft tissue malignant histiocytoma on the basis of determination of factors, influencing local recurrence development. Materials and methods: The basis of our study was a comprehensive analysis of examination and treatment results of 130 patients with MFH of the soft tissue of limbs, of them in 84 patients (64.6%) the recurrences developed. The group included 45 (53.6%) males and 39 (46.4%) females. The major part of patients – 82.1% (60 patients) were older than 40 years. Results and conclusions: The number of recurrences after the treatment in general surgical facilities is 86.9%, whereas in the patients after the treatment in the specialized oncological facilities this figure is twice lower (40%). The characteristic of the medical facility where the patient receives his/her primary treatment largely affects the development of local recurrences, patients’ quality of life and overall survival rates. The surgical method remains the leading modality in the treatment of MFH of ST. Wide and radical excision of tumors in the specialized oncological facilities allows achieving better survival outcomes of the patients.

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