Concentrations of booster biocides in sediment and clams from Vietnam

2006 ◽  
Vol 86 (5) ◽  
pp. 1163-1170 ◽  
Author(s):  
Hiroya Harino ◽  
Sayaka Midorikawa ◽  
Takaomi Arai ◽  
Madoka Ohji ◽  
Nguyen Duc Cu ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Simultaneous Determination ◽  
Analytical Method ◽  
Degradation Product ◽  
Detection Limits ◽  
Recovery Rates ◽  
Irgarol 1051 ◽  
Central Vietnam ◽  
Relative Standard

An analytical method for the simultaneous determination of five booster biocides (Sea-Nine 211, Dichlofluanid, Duiron, Irgarol 1051 and Pyrithiones) and degradation product of Irgarol 1051 (M1) in sediment from Vietnam was developed by LC/MS-MS. The recovery rates and relative standard deviation of the booster biocides in the sediment were in the range of 71–108% and 1.5–12%, respectively, and the detection limits were in the range of 0.04–2 μg kg−1 dry. An analytical method for the simultaneous determination of three booster biocides (Sea-Nine 211, Duiron and Irgarol 1051) and M1 in clams was also developed by LC/MS-MS. The recovery rates and relative standard deviations of the booster biocides in the biological samples were in the range of 60–99% and 3.4–6.8%, respectively, and the detection limits were in the range of 0.24–1.1 μg kg−1.The booster biocides in sediment from the coastal area of northern and central Vietnam were measured using this analytical method. Sea-Nine 211, Dichlofluanid, Duiron, Irgarol 1051, M1 and Pyrithiones were detected in the range of 0.09–1.3 μg kg−1 dry, <0.10–13 μg kg−1 dry, 0.11–3.0 μg kg−1 dry, 0.05–4.0 μg kg−1 dry, <0.1–0.43 μg kg−1 dry and <2–420 μg kg−1 dry, respectively. The detection frequencies of Dichlofluanid, M1 and Pyrithiones were low. The species and levels of detected booster biocides varied between sampling stations.Irgarol 1051 and its degradation product M1 were not detected in clams.

scholarly journals Application of Derivative Spectrophotometry for Simultaneous Determination of Quinapril and Hydrochlorothiazide in the Combination Tablets

2004 ◽  
Vol 87 (4) ◽  
pp. 847-851 ◽  
Author(s):  
Dorota Kowalczuk ◽  
Hanna Hopkała
Keyword(s):  
Standard Deviation ◽  
Simultaneous Determination ◽  
Relative Standard Deviation ◽  
Spectrophotometric Method ◽  
Derivative Spectrophotometry ◽  
Order Derivative ◽  
Zero Crossing ◽  
Relative Standard ◽  
Separation Of Components

Abstract A new second-order-derivative spectrophotometric method using zero-crossing technique measures quinapril (QUI) and hydrochlorothiazide (HYD) in 2-component mixtures. The procedure does not require prior separation of components from the sample. QUI was determined at a wavelength of 211.6 nm (zero-crossing wavelength point of HYD). Similarly, HYD was measured at 270.8 nm (zero-crossing wavelength point of QUI). Calibration graphs were constructed over the concentration range of 4.0 to 24.0 μ/mL for QUI and 2.5 to 15.0 μg/mL for HYD. Detection and quantitation limits were 0.85 and 2.5 μg/mL for QUI and 0.12 and 0.4 μg/mL for HYD, respectively. The accuracy (recovery 100.5–102%), precision (relative standard deviation less than 3.5% for QUI and 1.5% for HYD), selectivity, and sensitivity of the elaborated methods were satisfactory. The proposed method was applied successfully for the determination of both drugs in QUI-HYD tablets.

scholarly journals Simultaneous Determination of Free Carnitine and Total Choline by Liquid Chromatography/Mass Spectrometry in Infant Formula and Health-Care Products: Single-Laboratory Validation

2008 ◽  
Vol 91 (4) ◽  
pp. 777-785 ◽  
Author(s):  
Pierre Andrieux ◽  
Tamara Kilinc ◽  
Christian Perrin ◽  
Esther Campos-Giménez
Keyword(s):  
Health Care ◽  
Standard Deviation ◽  
Simultaneous Determination ◽  
Relative Standard Deviation ◽  
Infant Formula ◽  
Free Carnitine ◽  
Official Method ◽  
Relative Standard ◽  
Single Laboratory

Abstract A single-laboratory validation study was conducted for a liquid chromatographic/mass spectrometric (LC/MS) method for the simultaneous determination of the free carnitine and total choline in milk-based infant formula and health-care products. The sample preparation used for both carnitine and choline was adapted from AOAC Official Method 999.14, with an acidic and enzymatic hydrolysis of esterified forms of choline. Carnitine and choline were quantified by ion-pair chromatography with single-quadrupole MS detection, using their respective deuterated internal standards. The repeatability relative standard deviation was 2.5 and 2.1, respectively, for carnitine and choline. The intermediate reproducibility relative standard deviation was &lt;4.7 and 2.4, respectively, for carnitine and choline. The ranges of the average product-specific recoveries were 9298 and 94103, respectively, for carnitine and choline. Choline concentration determined in infant formula reference material SRM 1846 was in agreement with the reference value. The proposed method was compared with the enzymatic methods for a range of products; good correlation (r = 0.99) was obtained, although a significant bias was observed for both analytes. The method, with a short chromatographic run time (7 min), is convenient for routine analysis to enhance analytical throughput and is a good alternative to enzymatic assays.

scholarly journals Multiwavelength Spectral Correction for the Simultaneous Determination of Cu(II), Fe(II), and Zn(II) with 1-(5-Bromo-2-Pyridylazo)-2-Naphthol-6-Sulfonic Acid

2001 ◽  
Vol 84 (1) ◽  
pp. 532-536 ◽  
Author(s):  
Hong-Wen Gao
Keyword(s):  
Simultaneous Determination ◽  
Analytical Method ◽  
Sulfonic Acid ◽  
Free Ligand ◽  
Spectral Correction ◽  
Relative Standard ◽  
Zn And Cu In ◽  
Matrix Formula ◽  
Standard Deviations

Abstract A new analytical method is described for the simultaneous determination of various components by multiwavelength spectrophotometry. Because of the influence of the free ligand and various complexes on spectrophotometric absorption, the spectral correction principle was used to establish the calculation matrix formula. The 3 sensitive reactions of Cu(II), Fe(II), and Zn(II), with 1-(5-bromo-2-pyridylazo)-2-naphthol-6-sulfonic acid were studied at pH 10.5. In analyses of fortified samples, the recoveries of Fe, Zn, and Cu were between 93.0 and 103%, 87.0 and 108%, and 92.5 and 108%, respectively; the relative standard deviations for 5 determinations of Fe, Zn, and Cu in unfortified ore were 3.6, 5.8, and 4.5%, respectively.

Simultaneous Determination of Cationic and Anionic Surfactants in Domestic, Sewage and River Effluent by Diffuse Reflectance -Fourier Transform Infrared Spectroscop ic Analysis

2021 ◽  
Vol 30 (1) ◽  
pp. 32-40 ◽  
Author(s):  
Ramsingh Kurrey ◽  
Kaushlya Thakur ◽  
Swati Chandrawanshi ◽  
Manas Kanti Deb
Keyword(s):  
Fourier Transform ◽  
Standard Deviation ◽  
Simultaneous Determination ◽  
Diffuse Reflectance ◽  
Limit Of Detection ◽  
Sodium Dodecyl ◽  
Fourier Transform Infrared ◽  
Domestic Sewage ◽  
Relative Standard

A new, simple, rapid and precise novel hyphenated diffuse reflectance-Fourier transform infrared spectroscopy (DRS-FTIR) technique for the simultaneous determination of the most frequently used cationic surfactants (CS+) i.e. cetyltrimethylammonium bromide (CTAB) and anionic surfactant (AS-) i.e. sodium dodecyl sulphate (SDS) in domestic, sewage and river wastewater samples has been stabilised. CS+ and AS- were analyzed using DRS-FTIR, the most steady and strongest vibrational IR peak at 2917.13 cm-1 for CTAB and 1226.07 for SDS were selected for the simultaneous quantiflcation of CS+ and AS- under the optimized condition such as effect of samples volume and effect of temperature. The limit of detection (LOD) and limit of quantiflcation (LOQ) of the present method were 5 µg/mL and 15 µg/mL, respectively. The absorbance and peak area were determined by the DRS-FTIR method, which shows excellent linearity with a correlation coefflcient value of 0.985 and 0.981 for the concentration range of 10-100 µg/mL. The standard deviation (SD) and relative standard deviation (RSD) for six replicate measurements were found to be 0.052 µg/L and 2.8 %, respectively.

Colorimetric Determination of Arprinocid in Feed

1978 ◽  
Vol 61 (5) ◽  
pp. 1078-1082
Author(s):  
David W Fink ◽  
Kobert P Martin ◽  
James V Pivnichny ◽  
Jung-Sook K Shim
Keyword(s):  
Standard Deviation ◽  
Reaction Time ◽  
Analytical Method ◽  
Acidic Solution ◽  
Feed Additives ◽  
Colorimetric Determination ◽  
Colorimetric Measurement ◽  
Relative Standard ◽  
Zinc Reduction

Abstract An analytical method has been developed for the determination of arprinocid (9-(2-chloro- fluorophenylmethyl) -9ff-purin-6-amine) in feed, based upon measurement of the absorbance of the diazo chromophore formed from product of zinc reduction of the drug in acidic solution. The analyte is extracted from the feed into chloroform in the presence of a pH 7 phosphate buffer and isolated by adsorption chromatography on alumina, followed by partitioning between hexane and 0.15M HC1. The reduction product in the aqueous phase is then treated for colorimetric measurement. This procedure has been applied to determining 0.0010-0.0080% arprinocid in feed with precision of &lt;5% relative standard deviation near the middle of this concentration range. Of 32 feed additives examined, only zoalene and sulfamethazine were serious interferences. study and discussion of several factors, e.g., reaction time, pH, and amount of zinc metal, that affect the analytical reactions are also included.

scholarly journals Simultaneous Determination of Aflatoxins, Ochratoxin A, and Zearalenone in Grains by New Immunoaffinity Column/Liquid Chromatography

2004 ◽  
Vol 87 (2) ◽  
pp. 411-416 ◽  
Author(s):  
Roswitha Göbel ◽  
Klaus Lusky
Keyword(s):  
Column Liquid Chromatography ◽  
Liquid Chromatography ◽  
Simultaneous Determination ◽  
Ochratoxin A ◽  
Fluorescence Detection ◽  
Trifluoroacetic Acid ◽  
Detection Limits ◽  
Immunoaffinity Column ◽  
Recovery Rates

Abstract The simultaneous determination of mycotoxins was performed in 3 steps: extraction, cleanup, and detection. For extraction, a mixture of acetonitrile–water (60 + 40, v/v) was proved appropriate. For cleanup, a new Afla-Ochra-Zea immunoaffinity column was used. After derivatization with trifluoroacetic acid, the mycotoxins aflatoxins, ochratoxin A (OTA), and zearalenone (ZEA) were determined simultaneously by liquid chromatography with fluorescence detection. The detection limits in different matrixes after cleanup with the new immunoaffinity column were very low: aflatoxins, 0.002–0.7 μg/kg; OTA, 0.07–0.25 μg/kg; ZEA, 1–3 μg/kg. The limits of determination were: aflatoxins, 0.25 μg/kg; OTA, 0.5 μg/kg; ZEA, 5 μg/kg. The recovery rates for aflatoxins, OTA, and ZEA for rye and rice were between 86 and 93% when a 0.5 g sample matter per immunoaffinity column was used.

Determination of Nine Microelements in Nostoc commune Vauch by ICP-AES

2012 ◽  
Vol 518-523 ◽  
pp. 5020-5023 ◽  
Author(s):  
Yi Diao ◽  
Hong Bo Han ◽  
Da Fen Zhang ◽  
Jian Ping Zhou ◽  
Zu Jun Yang
Keyword(s):  
Toxic Elements ◽  
Detection Limits ◽  
Nostoc Commune ◽  
Recovery Rates ◽  
Relative Standard ◽  
Standard Deviations

In this paper,the contents of nine elements including Cu, Fe, Mn, Zn, Al, Cd, Pb, Ti and V were determined by ICP-AES technique, which elements originated from Nostoc commune Vauch from different places. Detection limits ranged 0.0018 ug•ml-1 and 0.068 ug•ml-1, the relative standard deviations for all these elements were lower than 2%, and recovery rates ranged 95.8% and 105.6%. The results showed that there were rich elements in N. commune Vauch from different places; contens of Fe, Al and V were highest; contents of Mn, Zn and Ti were moderately high,and contents of Cu, Cd and Pb were lowest. Futhermore, Cu, Fe, Mn, Zn and V were essential to people’s health,and Al, Cd, Pb and Ti had potentially physiologically toxic.Finally,Concentrations of elements within N. commune Vauch from different places were different,which may have some relations with the soil and environment where N. Commune grew.As a result, the determining method which elements of N. Commune are determined by ICP-AES is rapid,accurate and convenient, and wild N. Commune may contain toxic elements because of pollutional soil and environment,so N. Commun cultivated artificially can effectively reduce harmful elements.

scholarly journals SIMULTANEOUS DETERMINATION OF PARACETAMOL AND IBUPROFENE MIXTURES BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY

2010 ◽  
Vol 3 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Sophi Damayanti ◽  
Slamet Ibrahim ◽  
Kurnia Firman ◽  
Daryono H Tjahjono
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Standard Deviation ◽  
Retention Time ◽  
Analytical Method ◽  
Phosphate Buffer ◽  
Mobile Phase ◽  
High Performance ◽  
Relative Standard

Analytical method for the determination of paracetamol and ibuprofene mixtures has been developed by High Performance Liquid Chromatography using C-18 column and acetinitrile - phosphate buffer pH = 4.5 (75:25) containing 0.075% sodium hexanesulfunate as a mobile phase. The detector was set at 215 nm. Using such conditions, retention time for paracetamol and ibuprofen was 4.89 and 7.11 min, respectively. The recovery for paracetamol and ibuprofen was found to be 101.07± 0.73% and 102.02 ± 1.58%, respectively. The detector limits of the method was 1.30 and 1.60 μg/mL with the relative standard deviation (RSD) 0.74 and 1.52% for paracetamol and ibuprofen, respectively.   Keywords: paracetamol, ibuprofen, multi-component, validation, HPLC.

Determination of Microelements in Balanophora involucrate Hook. f. by ICP-AES

2014 ◽  
Vol 543-547 ◽  
pp. 1132-1135
Author(s):  
Hong Bo Han ◽  
Yi Diao ◽  
Hui Ping Wei ◽  
Shu Quan Wan ◽  
Da Fen Zhang
Keyword(s):  
Toxic Elements ◽  
Detection Limits ◽  
Recovery Rates ◽  
Relative Standard ◽  
Standard Deviations

In this paper, the contents of these elements including Cu, Fe, Mn, Zn, Al, Cd, Pb, Ti and As were determined by ICP-AES technique, which elements originated from B. involucrate from different places. Detection limits ranged 0.0029 ug/ml-1 and 0.079 ug/ml-1, the relative standard deviations for all these elements were lower than 2%, and recovery rates ranged 94.8% and 105.8%. The results showed that there were rich elements in B. involucrate from different places; contents of Fe and Al were highest; contents of Mn, Zn, Cu and Ti were moderately high, and contents of As, Cd and Pb were lowest. Futhermore, Cu, Fe, Mn, Zn were essential to peoples health, and Al, Cd, As, Pb and Ti had potentially physiologically toxic. Finally, concentrations of elements within B. involucrate from different places were different, which may have some relations with the environment where B.involucrate grew. As a result, the determining method which elements of B. involucrate. are determined by ICP-AES is rapid, accurate and convenient, and wild B. involucrate may contain toxic elements because of pollutional soil and environment, so B.involucrate cultivated artificially can effectively reduce harmful elements.

scholarly journals Simultaneous Determination of N-Butylscopolamine and Oxazepam in Pharmaceutical Formulations by First-Order Digital Derivative Spectrophotometry

2005 ◽  
Vol 88 (4) ◽  
pp. 1173-1178 ◽  
Author(s):  
Maria Inés Toral ◽  
Marcelo A Muñoz ◽  
Sandra L Orellana
Keyword(s):  
Standard Deviation ◽  
Simultaneous Determination ◽  
Relative Standard Deviation ◽  
Pharmaceutical Formulations ◽  
Derivative Spectrophotometry ◽  
Simple Method ◽  
Zero Crossing ◽  
First Order ◽  
Relative Standard

Abstract A simple method has been developed for the simultaneous determination of N-butylscopolamine bromide and oxazepam in pharmaceutical formulations using first-order digital derivative spectrophotometry. Acetonitrile was selected as the solvent in which both compounds showed well-defined bands. Both analytes showed good stability in this solvent when solutions of the analytes were exposed to light and temperatures between 20° and 80°C. The simultaneous determination of both drugs was performed by the zero-crossing method at 226.0 and 257.0 nm for N-butylscopolamine and oxazepam, respectively. The linear range of determination was found to be 2.5 × 10−7 to 8.0 × 10−5 mol/L for N-butylscopolamine and 7.1 × 10−8 to 8.0 × 10−5 mol/L for oxazepam. A very good level of repeatability (relative standard deviation) of 0.2% was observed for N-butylscopolamine and oxazepam. The ingredients commonly found in pharmaceutical formulations do not interfere. The proposed method was applied to the determination of these drugs in pharmaceutical formulations (capsules).

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