Impact of parental onchocerciasis and intensity of transmission on development and persistence ofOnchocerca volvulusinfection in offspring: an 18 year follow-up study

Parasitology ◽  
2003 ◽  
Vol 127 (4) ◽  
pp. 327-335 ◽  
Author(s):  
A. K. KIRCH ◽  
H. P. DUERR ◽  
B. BOATIN ◽  
W. S. ALLEY ◽  
W. H. HOFFMANN ◽  
...  
Keyword(s):  
Associated Factors ◽  
Multiple Logistic Regression Analysis ◽  
Infection Intensity ◽  
Control Programme ◽  
Multiple Logistic Regression ◽  
Transmission Potential ◽  
Follow Up Study ◽  
The Impact ◽  
Onchocerciasis Control

This study analysed the impact and the extent by which parentalOnchocerca volvulusinfection, intensity of transmission ofO. volvulusinfective 3rd-stage larvae (L3) and anthropometric factors may influence the acquisition, development and persistence ofO. volvulusinfection in offspring. A total of 15 290 individuals in 3939 families with 9640 children were surveyed for microfilariae ofO. volvulus, and prevalence and level ofO. volvulusinfection in children aged 0 to 20 years from infected and non-infected parents were followed longitudinally for 18 years. Children fromO. volvulus-infected mothers had not only a substantially higher risk to become infected; they also acquired infection earlier in life and developed higher infection levels. Multiple logistic regression analysis showed that maternalO. volvulusinfection and children's age are the predominant predictors for patentO. volvulusinfection, while the intensity of transmission, measured by the annual transmission potential (ATP) ofO. volvulusL3, was less decisive. Longitudinal follow up of children showed that during vector control activities by the Onchocerciasis Control Programme (OCP) and in low-level transmission areas, infection persisted at higher levels in children fromO. volvulus-positive mothers. In summary, the dominant risk factor for children to become infected is maternal onchocerciasis, and also age-associated factors will strongly impact on the development of patentO. volvulusinfection in offspring.

scholarly journals Patterns of epidemiology and control of onchocerciasis in West Africa

1997 ◽  
Vol 71 (2) ◽  
pp. 91-101 ◽  
Author(s):  
B. Boatin ◽  
D.H. Molyneux ◽  
J.M. Hougard ◽  
O.W. Christensen ◽  
E.S. Alley ◽  
...  
Keyword(s):  
West Africa ◽  
Vector Control ◽  
Control Strategies ◽  
Control Programme ◽  
Transmission Potential ◽  
The Public ◽  
And Control ◽  
Combined Impact ◽  
The Impact ◽  
Onchocerciasis Control

AbstractThis paper summarizes the work of the Onchocerciasis Control Programme (OCP) in West Africa, a programme which over a 22 year history has reduced the public health problems of blinding onchocerciasis in eleven countries of West Africa through vector control and, more recently, ivermectin distribution. The paper emphasizes the different approaches to control the programme has developed in the different parts of the programme area which have been determined by the epidemiology of the disease (savanna/forest form), the migratory characteristics of the vectors, intensity of the disease before commencement of treatment, the combined impact of vector control and ivermectin and the likelihood of infiltration of infective blackflies from outside the programme area. The programme has constantly monitored the impact of operations on the trends in prevalence, incidence, annual transmission potential, ocular morbidity and species of fly populations, and as a result, has identified areas where special interventions are required until the programme comes to an end in 2002. The paper illustrates the changes in intensity of infection as measured by community microfilarial load and annual transmission potential over the duration of the programme control activities. The paper also defines and justifies the control strategies in different areas and identifies areas for special interventions.

scholarly journals Onchocerciasis control in Ghana (1974–2016)

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Nana-Kwadwo Biritwum ◽  
Dziedzom K. de Souza ◽  
Odame Asiedu ◽  
Benjamin Marfo ◽  
Uche Veronica Amazigo ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Vector Control ◽  
Control Strategy ◽  
Financial Support ◽  
Control Programme ◽  
Ivermectin Treatment ◽  
Mobile Community ◽  
The Mean ◽  
The Impact ◽  
Onchocerciasis Control

Abstract Background The control of onchocerciasis in Ghana started in 1974 under the auspices of the Onchocerciasis Control Programme (OCP). Between 1974 and 2002, a combination of approaches including vector control, mobile community ivermectin treatment, and community-directed treatment with ivermectin (CDTI) were employed. From 1997, CDTI became the main control strategy employed by the Ghana OCP (GOCP). This review was undertaken to assess the impact of the control interventions on onchocerciasis in Ghana between 1974 and 2016, since which time the focus has changed from control to elimination. Methods In this paper, we review programme data from 1974 to 2016 to assess the impact of control activities on prevalence indicators of onchocerciasis. This review includes an evaluation of CDTI implementation, microfilaria (Mf) prevalence assessments and rapid epidemiological mapping of onchocerciasis results. Results This review indicates that the control of onchocerciasis in Ghana has been very successful, with a significant decrease in the prevalence of infection from 69.13% [95% confidence interval) CI 60.24–78.01] in 1975 to 0.72% (95% CI 0.19–1.26) in 2015. Similarly, the mean community Mf load decreased from 14.48 MF/skin snip in 1975 to 0.07 MF/skin snip (95% CI 0.00–0.19) in 2015. Between 1997 and 2016, the therapeutic coverage increased from 58.50 to 83.80%, with nearly 100 million ivermectin tablets distributed. Conclusions Despite the significant reduction in the prevalence of onchocerciasis in Ghana, there are still communities with MF prevalence above 1%. As the focus of the GOCP has changed from the control of onchocerciasis to its elimination, both guidance and financial support are required to ensure that the latter goal is met.

An overview of body weight of older persons, including the impact on mortality The national health and nutrition examination survey i-epidemiologic follow-up study

1991 ◽  
Vol 44 (8) ◽  
pp. 743-753 ◽  
Author(s):  
Joan C. Cornoni-Huntley ◽  
Tamara B. Harris ◽  
Donald F. Everett ◽  
Demetrius Albanes ◽  
Marc S. Micozzi ◽  
...  
Keyword(s):  
Body Weight ◽  
National Health ◽  
Older Persons ◽  
Nutrition Examination Survey ◽  
Follow Up Study ◽  
Health And Nutrition ◽  
The Impact

CPAP-SAVER follow-up study to determine long-term adherence and associated factors

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
April L. Shapiro ◽  
Joeli Olson ◽  
Saima Shafique ◽  
Ubolrat Piamjariyakul
Keyword(s):  
Associated Factors ◽  
Follow Up Study

scholarly journals Keeping the Flame Lit: The Value of the Long-Term Permanence of a Science Club

2018 ◽  
Vol 41 (1) ◽  
pp. 132-143
Author(s):  
Miguel García-Guerrero ◽  
Bertha Michel-Sandoval ◽  
Viridiana Esparza-Manrique ◽  
Amelia Rodríguez-Pinedo ◽  
Vianey Raudales-Hernández ◽  
...  
Keyword(s):  
Public Communication ◽  
Children And Young People ◽  
Follow Up Study ◽  
School Programs ◽  
Science Clubs ◽  
The Impact ◽  
Science Club ◽  
Science Activities

Science clubs are programs that allow people (especially children and youngsters) to meet regularly outside of school programs and engage with science and technology activities. Clubs encourage participants to foster attitudes, capabilities, and knowledge related to STEM fields with the goal of promoting interest and passion about science. As such programs provide big opportunities to improve the impact of public communication of science activities, it is really important to look at the impacts of such programs. Quark Group runs the Children Science Club since 2002, and up to 2016, it developed science recreation activities with 711 children and young people. In order to establish the influence the club had on its participants, we conducted a survey that provided 244 answers. This article presents the findings of this follow-up study.

Shifts in Fear of Success in Men and Women from 1968 to 1987

1987 ◽  
Vol 61 (1) ◽  
pp. 36-38 ◽  
Author(s):  
Darhl M. Pedersen ◽  
Tracy Conlin
Keyword(s):  
Women's Liberation ◽  
Fear Of Success ◽  
Cultural Changes ◽  
Men And Women ◽  
Follow Up Study ◽  
Women’S Liberation ◽  
Societal Changes ◽  
The Impact

A follow-up study on feat of success was completed 19 years after Horner collected her data in 1968. It was hypothesized that cultural changes relating to women's liberation would result in fewer women and more men exhibiting fear of success compared to Horner's findings. 25 men and 25 women were tested using Horner's procedures to facilitate comparisons. A higher percentage of men exhibited fear of success than Horner reported; however, the percentage of women remained about the same. Apparently, the impact of societal changes on men has been greater than on women.

The impact of cardiovascular diseases on hearing deterioration: a 13-year follow-up study

2021 ◽  
pp. 1-6
Author(s):  
Venla Lohi ◽  
Pasi Ohtonen ◽  
Martti Sorri ◽  
Elina Mäki-Torkko ◽  
Samuli Hannula
Keyword(s):  
Cardiovascular Diseases ◽  
Follow Up Study ◽  
The Impact
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