A controlled longitudinal 5-year follow-up study of children at high and low risk for panic disorder and major depression

Background. To evaluate the longitudinal course of psychiatric disorders in children of parents with panic disorder (PD) and major depression (MD) as they transition through the period of risk from childhood into adolescence.Method. Over a 5-year follow-up, we compared psychiatric disorders in four groups of children: (1) offspring of parents with PD plus MD (n=136); (2) offspring of parents with PD without MD (n=27); (3) offspring of parents with MD but without PD (n=53); and (4) offspring of non-PD non-MD parents (n=103).Results. Parental PD was significantly associated with increased risk for anxiety disorders, irrespective of parental MD. Parental MD was associated with increased risk for MD, disruptive behavior disorders, and deficits in psychosocial functioning, irrespective of parental PD.Conclusions. These longitudinal findings confirm and extend previous cross-sectional results documenting significant associations between PD and MD in parents and patterns of psychopathology and dysfunction in their offspring.

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Rate of psychiatric disorders and associations with quality of life among community members following the Kaohsiung gas explosion: an 18-month cross-sectional follow-up study

Health and Quality of Life Outcomes ◽

10.1186/s12955-018-1076-7 ◽

2019 ◽

Vol 17 (1) ◽

Cited By ~ 1

Author(s):

Vincent Shieh ◽

Joh-Jong Huang ◽

Tsyr-En Grace Wu ◽

Ju-Yu Chiu ◽

Yi-Chen Chen ◽

...

Keyword(s):

Quality Of Life ◽

Psychiatric Disorders ◽

Gas Explosion ◽

Community Members ◽

Cross Sectional ◽

Follow Up Study

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An Increased Risk of Stroke Among Panic Disorder Patients: A 3–Year Follow–up Study

Yearbook of Psychiatry and Applied Mental Health ◽

10.1016/j.ypsy.2010.10.089 ◽

2011 ◽

Vol 2011 ◽

pp. 292

Author(s):

J.C. Ballenger

Keyword(s):

Panic Disorder ◽

Follow Up Study ◽

Increased Risk

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An Increased Risk of Stroke among Panic Disorder Patients: A 3-Year Follow-up Study

The Canadian Journal of Psychiatry ◽

10.1177/070674371005500107 ◽

2010 ◽

Vol 55 (1) ◽

pp. 43-49 ◽

Cited By ~ 17

Author(s):

Yi-Hua Chen ◽

Chaur-Jong Hu ◽

Hsin-Chien Lee ◽

Herng-Ching Lin

Keyword(s):

Panic Disorder ◽

Follow Up Study ◽

Increased Risk

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A Community Survey of Quality of Life and Psychiatric Disorders among Residents Following the Kaohsiung Gas Explosion: a 5-Year Cross-Sectional Follow-Up Study

Psychiatric Quarterly ◽

10.1007/s11126-021-09911-0 ◽

2021 ◽

Author(s):

Han-Yun Chang ◽

Wei-Tse Hsu ◽

Pay-Jen Wu ◽

Guijing Lin ◽

Chun-Hua Cheng ◽

...

Keyword(s):

Quality Of Life ◽

Psychiatric Disorders ◽

Community Survey ◽

Gas Explosion ◽

Cross Sectional ◽

Follow Up Study

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P3624Prevalence and severity of coronary artery disease linked to prognosis in psoriasis patients referred for coronary computed tomography angiography: A multicentre cohort study

European Heart Journal ◽

10.1093/eurheartj/ehz745.0482 ◽

2019 ◽

Vol 40 (Supplement_1) ◽

Author(s):

A B Tinggaard ◽

K F Hjuler ◽

I T Andersen ◽

S Winther ◽

L Iversen ◽

...

Keyword(s):

Risk Factors ◽

Coronary Artery ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Follow Up Study ◽

Increased Risk ◽

All Cause Mortality ◽

Artery Disease

Abstract Background Psoriasis (Pso) is a disease characterized by systemic inflammation and is associated with an increased risk of cardiovascular disease. However, the degree of coronary artery calcification in Pso and its relation to prognosis is largely unknown. Purpose The aim of this study was 1) to estimate the prevalence and severity of coronary artery disease (CAD) in this patient group and 2) to asses the risk of major adverse cardiovascular events (MACE) including revascularization and all-cause mortality after initial diagnosis and treatment in a large-scale cohort of patients who underwent coronary computed tomography angiography (CCTA) due to angina symptoms. Methods This study consists of two parts using data from the Western Denmark Heart Registry; a cross-sectional study included 40,125 patients and a follow-up study included 42,861 patients. Pso patients were identified by the National Patient Registry and verified by nationwide prescription and treatment code registers. Primary outcome in the cross-sectional study was a coronary artery calcium score (CACS) >0, with a secondary outcome defined as a CACS ≥400. In the follow-up study, the primary outcome was a combined outcome including myocardial infarction, revascularization, ischemic or unspecified stroke and all-cause mortality. Events within the first 90 days after CCTA were attributed to initial treatment and consequently excluded. All outcomes were adjusted for common cardiovascular risk factors and comorbidities. Results In the cross-sectional study 1,407 (3.5%) Pso patients were identified. OR was 1.31 (95% CI; 1.15–1.49) for CACS >0 and 1.33 (95% CI; 1.10–1.62) for CACS ≥400 in Pso patients compared to non-Pso patients. In the follow-up study 1,591 (3.7%) Pso patients were identified. The mean duration of follow-up after CCTA was 4.0 years (min/max 0.0/10.2). Crude HR for the combined outcome was 1.52 (95% CI; 1.24–1.87), while adjusted HR was 1.16 (95% CI; 0.95–1.43). Conclusion In this clinically relevant cohort of patients referred to CCTA for CAD rule out, coronary artery calcification was more frequent and more severe in Pso patients even compared to the control patients with several risk factors and angina symptoms, but without inflammatory diseases. An increased risk of the combined outcome of MACE including revascularization and all-cause mortality after initial treatment in Pso patients was found in the crude analysis. The increased risk seemed predominantly carried by an increase in traditional risk factors.

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Lifetime experience of multiple common mental disorders and 19-year mortality: results from a Canadian population-based cohort

Epidemiology and Psychiatric Sciences ◽

10.1017/s2045796018000859 ◽

2019 ◽

Vol 29 ◽

Author(s):

M. Kingsbury ◽

E. Sucha ◽

N. J. Horton ◽

H. Sampasa-Kanyinga ◽

J. M. Murphy ◽

...

Keyword(s):

Major Depression ◽

Alcohol Use ◽

Mental Disorders ◽

Panic Disorder ◽

Psychiatric Disorders ◽

Alcohol Use Disorders ◽

Risk Of Death ◽

Risk Of Mortality ◽

Increased Risk ◽

The Impact

Abstract Aims To examine the impact of multiple psychiatric disorders over the lifetime on risk of mortality in the general population. Methods Data came from a random community-based sample of 1397 adults in Atlantic Canada, recruited in 1992. Major depression, dysthymia, panic disorder, generalised anxiety disorder and alcohol use disorders were assessed using the Diagnostic Interview Schedule (DIS). Vital status of participants through 2011 was determined using probabilistic linkages to the Canadian Mortality Database. Cox proportional hazard models with age at study entry as the time scale were used to investigate the relationship between DIS diagnoses and mortality, adjusted for participant education, smoking and obesity at baseline. Results Results suggested that mood and anxiety disorders rarely presented in isolation – the majority of participants experienced multiple psychiatric disorders over the lifetime. Elevated risk of death was found among men with both major depression and dysthymia (HR 2.56; 95% CI 1.12–5.89), depression and alcohol use disorders (HR 2.45; 95% CI 1.18–5.10) and among men and women who experienced both panic disorder and alcohol use disorders (HR 3.80; 95% CI 1.19–12.16). Conclusion The experience of multiple mental disorders over the lifetime is extremely common, and associated with increased risk of mortality, most notably among men. Clinicians should be aware of the importance of considering contemporaneous symptoms of multiple psychiatric conditions.

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