Neural plasticity in response to attention training in anxiety

2009 ◽  
Vol 40 (4) ◽  
pp. 667-677 ◽  
Author(s):  
S. Eldar ◽  
Y. Bar-Haim
Keyword(s):  
Neural Plasticity ◽  
A Priori ◽  
Mean Amplitude ◽  
Event Related Potential ◽  
Attention Training ◽  
Training Procedure ◽  
Threat Bias ◽  
Top Down ◽  
Attentional Processes ◽  
Behavioral Studies

BackgroundBehavioral studies show that attention training can alter threat bias, influence vulnerability to stress and reduce clinical anxiety symptoms. The aim of this study was to examine which cognitive functions of attention processing are modulated by attention training, and how a priori anxiety interacts with the attention training procedure. Specifically, we expected modulation in the P1/N1 event-related potential (ERP) complex if early spatial attention was to be affected by training and modulation in later ERP components (P2, N2, P3) had training affected top-down attentional processes.MethodThirty anxious and 30 non-anxious adults performed a modified probe detection task. Electroencephalograms (EEGs) were recorded throughout for later ERP analyses. Half the participants in each anxiety group were randomly assigned to undergo a training procedure designed to divert their attention away from threat and the other half received placebo training.ResultsAnxious participants who were trained to avoid threat showed a linear reduction in response time (RT) to targets replacing neutral faces with the progression of training. This change in RT was not observed among non-anxious participants or among anxious participants who were exposed to placebo training. Following training, the anxious participants who were trained to avoid threat showed a reduction in P2 and P3 mean amplitudes and an enhancement in N2 mean amplitude.ConclusionsAttention training affects anxious participants whereas non-anxious participants seem not to respond to it. The ERP data suggest that attention training modulates top-down processes of attention control rather than processes of early attention orienting.

scholarly journals Defining the Role of Attention in Hierarchical Auditory Processing

2021 ◽  
Vol 11 (1) ◽  
pp. 112-128
Author(s):  
Caitlin N. Price ◽  
Deborah Moncrieff
Keyword(s):  
Auditory Processing ◽  
Auditory Pathway ◽  
Simultaneous Recording ◽  
Neural Encoding ◽  
Top Down ◽  
Attentional Processes ◽  
Clinical Interventions ◽  
Speech In Noise ◽  
Behavioral Studies ◽  
Electrophysiological Studies

Communication in noise is a complex process requiring efficient neural encoding throughout the entire auditory pathway as well as contributions from higher-order cognitive processes (i.e., attention) to extract speech cues for perception. Thus, identifying effective clinical interventions for individuals with speech-in-noise deficits relies on the disentanglement of bottom-up (sensory) and top-down (cognitive) factors to appropriately determine the area of deficit; yet, how attention may interact with early encoding of sensory inputs remains unclear. For decades, attentional theorists have attempted to address this question with cleverly designed behavioral studies, but the neural processes and interactions underlying attention’s role in speech perception remain unresolved. While anatomical and electrophysiological studies have investigated the neurological structures contributing to attentional processes and revealed relevant brain–behavior relationships, recent electrophysiological techniques (i.e., simultaneous recording of brainstem and cortical responses) may provide novel insight regarding the relationship between early sensory processing and top-down attentional influences. In this article, we review relevant theories that guide our present understanding of attentional processes, discuss current electrophysiological evidence of attentional involvement in auditory processing across subcortical and cortical levels, and propose areas for future study that will inform the development of more targeted and effective clinical interventions for individuals with speech-in-noise deficits.

scholarly journals The Role of Primate Prefrontal Cortex in Bias and Shift Between Visual Dimensions

2019 ◽  
Vol 30 (1) ◽  
pp. 85-99 ◽  
Author(s):  
Farshad A Mansouri ◽  
Mark J Buckley ◽  
Daniel J Fehring ◽  
Keiji Tanaka
Keyword(s):  
Prefrontal Cortex ◽  
Anterior Cingulate ◽  
Top Down ◽  
Attentional Processes ◽  
Prefrontal Cortical ◽  
Frontopolar Cortex ◽  
Dorsolateral Prefrontal ◽  
Cortical Regions ◽  
Visual Cortical ◽  
Bilateral Lesions

Abstract Imaging and neural activity recording studies have shown activation in the primate prefrontal cortex when shifting attention between visual dimensions is necessary to achieve goals. A fundamental unanswered question is whether representations of these dimensions emerge from top-down attentional processes mediated by prefrontal regions or from bottom-up processes within visual cortical regions. We hypothesized a causative link between prefrontal cortical regions and dimension-based behavior. In large cohorts of humans and macaque monkeys, performing the same attention shifting task, we found that both species successfully shifted between visual dimensions, but both species also showed a significant behavioral advantage/bias to a particular dimension; however, these biases were in opposite directions in humans (bias to color) versus monkeys (bias to shape). Monkeys’ bias remained after selective bilateral lesions within the anterior cingulate cortex (ACC), frontopolar cortex, dorsolateral prefrontal cortex (DLPFC), orbitofrontal cortex (OFC), or superior, lateral prefrontal cortex. However, lesions within certain regions (ACC, DLPFC, or OFC) impaired monkeys’ ability to shift between these dimensions. We conclude that goal-directed processing of a particular dimension for the executive control of behavior depends on the integrity of prefrontal cortex; however, representation of competing dimensions and bias toward them does not depend on top-down prefrontal-mediated processes.

scholarly journals An historical framework for psychiatric nosology

2009 ◽  
Vol 39 (12) ◽  
pp. 1935-1941 ◽  
Author(s):  
K. S. Kendler
Keyword(s):  
Psychiatric Illness ◽  
Theoretical Orientation ◽  
A Priori ◽  
Early History ◽  
Top Down ◽  
Species Definition ◽  
Psychiatric Nosology ◽  
Bottom Up ◽  
Starting Point ◽  
History Of

This essay, which seeks to provide an historical framework for our efforts to develop a scientific psychiatric nosology, begins by reviewing the classificatory approaches that arose in the early history of biological taxonomy. Initial attempts at species definition used top-down approaches advocated by experts and based on a few essential features of the organism chosena priori. This approach was subsequently rejected on both conceptual and practical grounds and replaced by bottom-up approaches making use of a much wider array of features. Multiple parallels exist between the beginnings of biological taxonomy and psychiatric nosology. Like biological taxonomy, psychiatric nosology largely began with ‘expert’ classifications, typically influenced by a few essential features, articulated by one or more great 19th-century diagnosticians. Like biology, psychiatry is struggling toward more soundly based bottom-up approaches using diverse illness characteristics. The underemphasized historically contingent nature of our current psychiatric classification is illustrated by recounting the history of how ‘Schneiderian’ symptoms of schizophrenia entered into DSM-III. Given these historical contingencies, it is vital that our psychiatric nosologic enterprise be cumulative. This can be best achieved through a process of epistemic iteration. If we can develop a stable consensus in our theoretical orientation toward psychiatric illness, we can apply this approach, which has one crucial virtue. Regardless of the starting point, if each iteration (or revision) improves the performance of the nosology, the eventual success of the nosologic process, to optimally reflect the complex reality of psychiatric illness, is assured.

scholarly journals Auditory attention alterations in migraine: a behavioral and MEG/EEG study

2019 ◽  
Author(s):  
Rémy Masson ◽  
Yohana Lévêque ◽  
Geneviève Demarquay ◽  
Hesham ElShafei ◽  
Lesly Fornoni ◽  
...  
Keyword(s):  
Event Related Potentials ◽  
Orienting Response ◽  
List Type ◽  
Top Down ◽  
Attention Task ◽  
Bottom Up ◽  
Attentional Processes ◽  
Related Potentials ◽  
The Right ◽  
Task Irrelevant

AbstractObjectivesTo evaluate alterations of top-down and/or bottom-up attention in migraine and their cortical underpinnings.Methods19 migraineurs between attacks and 19 matched control participants performed a task evaluating jointly top-down and bottom-up attention, using visually-cued target sounds and unexpected task-irrelevant distracting sounds. Behavioral responses and MEG/EEG were recorded. Event-related potentials and fields (ERPs/ERFs) were processed and source reconstruction was applied to ERFs.ResultsAt the behavioral level, neither top-down nor bottom-up attentional processes appeared to be altered in migraine. However, migraineurs presented heightened evoked responses following distracting sounds (orienting component of the N1 and Re-Orienting Negativity, RON) and following target sounds (orienting component of the N1), concomitant to an increased recruitment of the right temporo-parietal junction. They also displayed an increased effect of the cue informational value on target processing resulting in the elicitation of a negative difference (Nd).ConclusionsMigraineurs appear to display increased bottom-up orienting response to all incoming sounds, and an enhanced recruitment of top-down attention.SignificanceThe interictal state in migraine is characterized by an exacerbation of the orienting response to attended and unattended sounds. These attentional alterations might participate to the peculiar vulnerability of the migraine brain to all incoming stimuli.HighlightsMigraineurs performed as well as healthy participants in an attention task.However, EEG markers of both bottom-up and top-down attention are increased.Migraine is also associated with a facilitated recruitment of the right temporo-parietal junction.

scholarly journals ERP CORE: An Open Resource for Human Event-Related Potential Research

2020 ◽  
Author(s):  
Emily S. Kappenman ◽  
Jaclyn Farrens ◽  
Wendy Zhang ◽  
Andrew X Stewart ◽  
Steven J Luck
Keyword(s):  
Data Processing ◽  
Brain Activity ◽  
A Priori ◽  
Event Related Potentials ◽  
Event Related Potential ◽  
Error Related Negativity ◽  
Wide Range ◽  
Experiment Control ◽  
Related Potentials

Event-related potentials (ERPs) are noninvasive measures of human brain activity that index a range of sensory, cognitive, affective, and motor processes. Despite their broad application across basic and clinical research, there is little standardization of ERP paradigms and analysis protocols across studies. To address this, we created ERP CORE (Compendium of Open Resources and Experiments), a set of optimized paradigms, experiment control scripts, data processing pipelines, and sample data (N = 40 neurotypical young adults) for seven widely used ERP components: N170, mismatch negativity (MMN), N2pc, N400, P3, lateralized readiness potential (LRP), and error-related negativity (ERN). This resource makes it possible for researchers to 1) employ standardized ERP paradigms in their research, 2) apply carefully designed analysis pipelines and use a priori selected parameters for data processing, 3) rigorously assess the quality of their data, and 4) test new analytic techniques with standardized data from a wide range of paradigms.

scholarly journals Exploring the Effects of Visual Perspective on the ERP Components of Empathy for Pain

2019 ◽  
Author(s):  
Carl Michael Orquiola Galang ◽  
Sukhvinder S. Obhi ◽  
Michael Jenkins
Keyword(s):  
Mean Amplitude ◽  
Event Related Potential ◽  
Visual Perspective ◽  
First Person ◽  
Affective Component ◽  
Cognitive Components ◽  
Person Perspective ◽  
Empathy For Pain ◽  
Third Person ◽  
Third Person Perspective

Previous neurophysiological research suggests that there are event-related potential (ERP) components are associated with empathy for pain: early affective component (N2) and two late cognitive components (P3/LPP). The current study investigated whether and how the visual perspective from which a painful event is observed affects these ERP components. Participants viewed images of hands in pain vs. not in pain from a first-person or third-person perspective. We found that visual perspective influences both the early and late components. In the early component (N2), there was a larger mean amplitude during observation of pain vs no-pain exclusively when images were shown from a first-person perspective. We suggest that this effect may be driven by misattributing the on-screen hand to oneself. For the late component (P3), we found a larger effect of pain on mean amplitudes in response to third-person relative to first-person images. We speculate that the P3 may reflect a later process that enables effective recognition of others’ pain in the absence of misattribution. We discuss our results in relation to self- vs other-related processing by questioning whether these ERP components are truly indexing empathy (an other-directed process) or a simple misattribution of another’s pain as one’s own (a self-directed process).

scholarly journals Etnografía y políticas públicas en materia de justicia y violencia contra las mujeres en Chile.

2020 ◽  
Vol 19 (55) ◽  
Author(s):  
Fabiola Miranda Pérez ◽  
Daniella Gac Jiménez
Keyword(s):  
A Priori ◽  
Top Down ◽  
Las Mujeres

El presente análisis busca reflexionar sobre los aportes de la etnografía al estudio de las políticas públicas utilizando como ejemplo el caso de la intervención estatal en materia de violencia contra las mujeres en Chile en la última década. Para lo anterior, se expone aquí un trabajo etnográfico realizado en Tribunales de Familia en la Región Metropolitana, siguiendo casos de violencia conyugal, que combina observación directa con observación participante. Se sugiere la idea que la metodología etnográfica resulta substancial a la hora de aprehender la fase de implementación de las políticas públicas, ya que permite develar problemáticas y desigualdades que van más allá de aquellas que se presentan en el contacto entre el Estado y los/as usuarios/as, revelando además conflictos de legitimidad internos que las metodologías más clásicas de la Ciencia Política de corte top down no hubiesen a priori sacar a relucir. De esta manera se concluye que la etnografía no sólo se rinde cuenta de las modalidades de intervención, si no que también se avanza en el conocimiento del “Estado en acción” lo cual permitió mejorar la comprensión de las barreras que ha tenido desde la Justicia el estudio de las violencias contra las mujeres en este país.

scholarly journals Early Event-related Potential Effects of Syllabic Processing during Visual Word Recognition

2005 ◽  
Vol 17 (11) ◽  
pp. 1803-1817 ◽  
Author(s):  
Manuel Carreiras ◽  
Marta Vergara ◽  
Horacio Barber
Keyword(s):  
Word Recognition ◽  
Visual Word Recognition ◽  
Time Window ◽  
Low Frequency ◽  
Event Related Potential ◽  
Visual Word ◽  
Early Event ◽  
New Paradigm ◽  
Behavioral Studies ◽  
N400 Component

A number of behavioral studies have suggested that syllables might play an important role in visual word recognition in some languages. We report two event-related potential (ERP) experiments using a new paradigm showing that syllabic units modulate early ERP components. In Experiment 1, words and pseudowords were presented visually and colored so that there was a match or a mismatch between the syllable boundaries and the color boundaries. The results showed color-syllable congruency effects in the time window of the P200. Lexicality modulated the N400 amplitude, but no effects of this variable were obtained at the P200 window. In Experiment 2, high-and low-frequency words and pseudowords were presented in the congruent and incongruent conditions. The results again showed congruency effects at the P200 for low-frequency words and pseudowords, but not for high-frequency words. Lexicality and lexical frequency effects showed up at the N400 component. The results suggest a dissociation between syllabic and lexical effects with important consequences for models of visual word recognition.

A Survey on Ontology Creation Methodologies

2011 ◽  
pp. 98-122 ◽  
Author(s):  
Matteo Cristani ◽  
Roberta Cuel
Keyword(s):  
Artificial Intelligence ◽  
Knowledge Management ◽  
Information Systems ◽  
Current Literature ◽  
A Priori ◽  
Top Down ◽  
Specific Context ◽  
Systematic Analysis ◽  
General Terms ◽  
The Right

In the current literature of knowledge management and artificial intelligence, several different approaches to the problem have been carried out of developing domain ontologies from scratch. All these approaches deal fundamentally with three problems: (1) providing a collection of general terms describing classes and relations to be employed in the description of the domain itself; (2) organizing the terms into a taxonomy of the classes by the ISA relation; and (3) expressing in an explicit way the constraints that make the ISA pairs meaningful. Though a number of such approaches can be found, no systematic analysis of them exists which can be used to understand the inspiring motivation, the applicability context, and the structure of the approaches. In this paper, we provide a framework for analyzing the existing methodologies that compares them to a set of general criteria. In particular, we obtain a classification based upon the direction of ontology construction; bottom-up are those methodologies that start with some descriptions of the domain and obtain a classification, while top-down ones start with an abstract view of the domain itself, which is given a priori. The resulting classification is useful not only for theoretical purposes but also in the practice of deployment of ontologies in Information Systems, since it provides a framework for choosing the right methodology to be applied in the specific context, depending also on the needs of the application itself.

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