scholarly journals Stress-related anhedonia is associated with ventral striatum reactivity to reward and transdiagnostic psychiatric symptomatology

2015 ◽  
Vol 45 (12) ◽  
pp. 2605-2617 ◽  
Author(s):  
N. S. Corral-Frías ◽  
Y. S. Nikolova ◽  
L.J. Michalski ◽  
D. A. A. Baranger ◽  
A. R. Hariri ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Alcohol Use ◽  
Structural Equation ◽  
Ventral Striatum ◽  
Structural Equation Models ◽  
Depression Symptoms ◽  
Problematic Alcohol ◽  
Increased Risk ◽  
Problematic Alcohol Use ◽  
The Relationship

BackgroundEarly life stress (ELS) is consistently associated with increased risk for subsequent psychopathology. Individual differences in neural response to reward may confer vulnerability to stress-related psychopathology. Using data from the ongoing Duke Neurogenetics Study, the present study examined whether reward-related ventral striatum (VS) reactivity moderates the relationship between retrospectively reported ELS and anhedonic symptomatology. We further assessed whether individual differences in reward-related VS reactivity were associated with other depressive symptoms and problematic alcohol use via stress-related anhedonic symptoms and substance use-associated coping.MethodBlood oxygen level-dependent functional magnetic resonance imaging (fMRI) was collected while participants (n = 906) completed a card-guessing task, which robustly elicits VS reactivity. ELS, anhedonic symptoms, other depressive symptoms, coping behavior, and alcohol use behavior were assessed with self-report questionnaires. Linear regressions were run to examine whether VS reactivity moderated the relationship between ELS and anhedonic symptoms. Structural equation models examined whether this moderation was indirectly associated with other depression symptoms and problematic alcohol use through its association with anhedonia.ResultsAnalyses of data from 820 participants passing quality control procedures revealed that the VS × ELS interaction was associated with anhedonic symptoms (p = 0.011). Moreover, structural equation models indirectly linked this interaction to non-anhedonic depression symptoms and problematic alcohol use through anhedonic symptoms and substance-related coping.ConclusionsThese findings suggest that reduced VS reactivity to reward is associated with increased risk for anhedonia in individuals exposed to ELS. Such stress-related anhedonia is further associated with other depressive symptoms and problematic alcohol use through substance-related coping.

scholarly journals Memory Deficits Precede Increases in Depressive Symptoms in Later Adulthood

2018 ◽  
Vol 74 (6) ◽  
pp. 943-953 ◽  
Author(s):  
Stephen Aichele ◽  
Paolo Ghisletta
Keyword(s):  
Depressive Symptoms ◽  
Sex Education ◽  
Structural Equation ◽  
Structural Equation Models ◽  
Memory Performance ◽  
Memory Deficits ◽  
Community Dwelling ◽  
Depression Symptoms ◽  
Age Related ◽  
Increased Risk

Abstract Objectives We examined bidirectional, time-ordered associations between age-related changes in depressive symptoms and memory. Method Data came from 107,599 community-dwelling adults, aged 49–90 years, who participated in the Survey of Health, Ageing, and Retirement in Europe (SHARE). Depressive symptoms were measured with the EURO-D inventory, and memory was evaluated as delayed recall of a 10-word list. Participants were assessed up to five times at 2-year intervals. Dynamic structural equation models were used to estimate longitudinal and time-ordered (lead-lag) relations between depressive symptoms and memory performance. Results Depressive symptoms increased and memory scores decreased across the observed age range, with worsening mostly evident after age 62 years. These long-term changes were moderately negatively correlated (r = −.53, p < .001). A time-ordered effect emerged such that age-specific memory deficits preceded shorter-term increases in depression symptoms. This effect can be translated such that each 1-point decrement on a 10-point memory scale at a given age predicted a 14.5% increased risk for depression two years later. Statistical adjustment for covariates (sex, education, re-test, smoking, and body mass index) had little influence on these associations. Conclusion In later adulthood, lower memory performance at a given age predicts subsequent 2-year increases in depressive symptoms.

Problematic Alcohol Use and Suicidal Ideation Among Firefighters: A Multi-Study Investigation of the Explanatory Roles of Perceived Burdensomeness and Thwarted Belongingness

2018 ◽  
Author(s):  
Austin James Gallyer ◽  
Sean Patrick Dougherty ◽  
Anna R. Gai ◽  
Ian H. Stanley ◽  
Melanie A. Hom ◽  
...  
Keyword(s):  
Suicidal Ideation ◽  
Alcohol Use ◽  
Interpersonal Theory ◽  
Thwarted Belongingness ◽  
Perceived Burdensomeness ◽  
Symptom Index ◽  
Problematic Alcohol ◽  
Increased Risk ◽  
Problematic Alcohol Use ◽  
The Relationship

Background: Firefighters are at increased risk for both problematic alcohol use and suicidality. Research has found that problematic alcohol use is related to suicidality among this population; however, limited data exist regarding what might account for this association. The present two-study investigation (1) examined the association between suicidality and problematic alcohol use among two large samples of current firefighters and (2) tested whether interpersonal theory of suicide constructs—perceived burdensomeness (PB) and thwarted belongingness (TB)—serve as indirect indicators of this relationship. Methods: Participants in Study 1 were 944 U.S. firefighters (12.5% female); participants in Study 2 were 241 U.S. women firefighters. Participants completed the Interpersonal Needs Questionnaire, Alcohol Use Disorders Identification Test, and the Depressive Symptom Index: Suicidality Subscale (Study 1) or the Self-Injurious Thoughts and Behaviors Interview (Study 2). Bias-corrected bootstrap indirect effects path analyses were utilized. Results: In Study 1, more problematic alcohol use was significantly associated with more severe career suicidal ideation via PB but not TB. In Study 2, problematic alcohol use was associated with career suicidal ideation via both PB and TB. PB seems to account for the relationship between problematic alcohol use and career suicidal ideation among male and female firefighters. Limitations: Limitations include use of a cross-sectional design, use of retrospective measures of suicidal ideation, and our findings were derived from subsamples of two existing datasets. Conclusions: Findings suggest that PB and TB may explain the relationship between problematic alcohol use and suicidal ideation, but that this effect is discrepant based on gender.

scholarly journals Drinking Motives Mediate the Relationship Between Facets of Mindfulness and Problematic Alcohol Use

Mindfulness ◽  
2016 ◽  
Vol 7 (3) ◽  
pp. 754-763 ◽  
Author(s):  
Christine Vinci ◽  
Claire A. Spears ◽  
MacKenzie R. Peltier ◽  
Amy L. Copeland
Keyword(s):  
Alcohol Use ◽  
Drinking Motives ◽  
Problematic Alcohol ◽  
Problematic Alcohol Use ◽  
The Relationship

scholarly journals Perceived control of anxiety as a moderator in the relationship between anxiety sensitivity and problematic alcohol use among adolescents

2018 ◽  
Vol 63 ◽  
pp. 41-50 ◽  
Author(s):  
Nathan T. Kearns ◽  
Deyaun Villarreal ◽  
Renee M. Cloutier ◽  
Catherine Baxley ◽  
Caitlyn Carey ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Anxiety Sensitivity ◽  
Perceived Control ◽  
Problematic Alcohol ◽  
Problematic Alcohol Use ◽  
The Relationship

The relationship between caregiving self-efficacy and depressive symptoms in family caregivers of patients with Alzheimer disease: a longitudinal study

2017 ◽  
Vol 29 (7) ◽  
pp. 1095-1103 ◽  
Author(s):  
Caterina Grano ◽  
Fabio Lucidi ◽  
Cristiano Violani
Keyword(s):  
Depressive Symptoms ◽  
Caregiver Burden ◽  
Self Efficacy ◽  
Structural Equation ◽  
Structural Equation Models ◽  
Initial Assessment ◽  
Negative Consequences ◽  
Considerable Length ◽  
One Year ◽  
The Relationship

ABSTRACTBackground:Caregiving for a relative with dementia has been associated with negative consequences for mental health. Self-efficacy has been shown to correlate negatively with depression but the long-term association between caregiver burden, caregiver self-efficacy, and depressive symptoms, remains still largely unexplored. The aim of the present study was to evaluate whether different self-efficacy domains partially mediated the relationship between caregiving burden and depression.Methods:A three-wave design was used, with initial assessment and follow-ups three months later and one year later. One hundred seventy caregivers of patients with AD responded to measures of caregiver burden, caregiving self-efficacy, and depressive symptoms. Data were analyzed by means of structural equation models.Results:The tested model provided support for the guiding hypothesis. Burden at the time of the first assessment (T1) significantly influenced depression one year later and the relationship between burden at time one and depressive symptoms one year later was partially mediated by self-efficacy for controlling upsetting thoughts.Conclusions:The findings of the present study provide evidence that, along a considerable length of time, the effects of caregiver burden on depressive symptoms can be explained by the caregivers’ efficacy beliefs in controlling upsetting thoughts related to the caregiving tasks. Interventions for caregivers of patients with AD may help them in tackling negative thoughts about the caregiving role.

scholarly journals Mechanisms Underlying the Relationship between Negative Affectivity and Problematic Alcohol Use

2013 ◽  
Vol 4 (3) ◽  
pp. 263-278 ◽  
Author(s):  
Ayca Coskunpinar ◽  
Allyson L. Dir ◽  
Kenny A. Karyadi ◽  
ChungSeung Koo ◽  
Melissa A. Cyders
Keyword(s):  
Alcohol Use ◽  
Negative Affectivity ◽  
Problematic Alcohol ◽  
Problematic Alcohol Use ◽  
The Relationship

scholarly journals Heterogeneous Trajectories of Problematic Alcohol Use, Depressive Symptoms, and their Co-Occurrence in Young Adults with and without Childhood ADHD

2020 ◽  
Vol 48 (10) ◽  
pp. 1265-1277
Author(s):  
Frances L. Wang ◽  
Sarah L. Pedersen ◽  
Bernie Devlin ◽  
Elizabeth M. Gnagy ◽  
William E. Pelham ◽  
...  
Keyword(s):  
Young Adults ◽  
Depressive Symptoms ◽  
Alcohol Use ◽  
Childhood Adhd ◽  
Problematic Alcohol ◽  
Problematic Alcohol Use

Self-Criticism and Self-Warmth: An Imagery Study Exploring Their Relation to Depression

2006 ◽  
Vol 20 (2) ◽  
pp. 183-200 ◽  
Author(s):  
Paul Gilbert ◽  
Mark W. Baldwin ◽  
Chris Irons ◽  
Jodene R. Baccus ◽  
Michelle Palmer
Keyword(s):  
Depressive Symptoms ◽  
Data Analysis ◽  
Structural Equation ◽  
Structural Equation Models ◽  
The Self ◽  
Therapeutic Interventions ◽  
Imagery Task ◽  
Increased Risk ◽  
Negative Feelings

When things go wrong for people, those who are self-critical, compared to those who self-reassure, are at increased risk of psychopathology. However, little is known of the internal processes involved in self-criticism and self-reassurance, such as the ease of eliciting critical imagery, and the power, emotion and vividness of self-criticalness and self-reassurance. This study used a self-imagery task to investigate trait self-criticism and trait self-reassurance in relation to the ease and clarity of generating self-critical and self-reassuring images, and the felt power and emotion of self-critical and self-reassuring imagery. We also explored these in relation to depressive symptoms in students. Results suggested that trait self-criticism is associated with ease and clarity in generating hostile and powerful self-critical images, while trait self-reassurance is associated with ease and clarity of generating warm and supportive images of the self. Data analysis using structural equation models also suggests that difficulties in generating self-reassurance and compassionate images about the self with self-directed warmth, may also contribute to depressive symptoms. Thus self-critics may not only suffer for elevated negative feelings about the self but may also struggle to be able to generate self-supportive images and feelings for the self, and these difficulties could be a focus of therapeutic interventions.

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