DNA Diagnosis in Monogenic Diseases
1994 ◽
Vol 10
(4)
◽
pp. 628-643
◽
Keyword(s):
AbstractSeveral routine procedures are available for diagnosis of diseases caused by an alteration in a single gene. These techniques include Southern analysis, the polymerase chain reaction, allele-specific oligonucleotide screening, automated DNA nucleotide sequencing, and linkage analysis. DNA testing procedures can be used for diagnosis of disease, determination of carrier status in affected families, or general screening of the population. Some of the more commonly used techniques and their applications are described in this article.
1990 ◽
Vol 36
(12)
◽
pp. 2113-2117
◽
Determination of bovine alpha S1-casein alleles B and C by allele-specific polymerase chain reaction
1992 ◽
Vol 109
(1-6)
◽
pp. 316-319
◽
Keyword(s):
Keyword(s):
1987 ◽
Vol 166
(2)
◽
pp. 444-460
◽
Keyword(s):