scholarly journals Novel word learning at 21 months predicts receptive vocabulary outcomes in later childhood

2019 ◽  
Vol 46 (04) ◽  
pp. 617-631
Author(s):  
Vinaya RAJAN ◽  
Haruka KONISHI ◽  
Katherine RIDGE ◽  
Derek M. HOUSTON ◽  
Roberta Michnick GOLINKOFF ◽  
...  
Keyword(s):  
Word Learning ◽  
Cognitive Abilities ◽  
Parent Report ◽  
Receptive Vocabulary ◽  
Language Outcomes ◽  
Phoneme Discrimination ◽  
Novel Objects ◽  
Novel Word Learning

AbstractSeveral aspects of early language skills, including parent-report measures of vocabulary, phoneme discrimination, speech segmentation, and speed of lexical access predict later childhood language outcomes. To date, no studies have examined the long-term predictive validity of novel word learning. We examined whether individual differences in novel word learning at 21 months predict later childhood receptive vocabulary outcomes rather than generalized cognitive abilities. Twenty-eight 21-month-olds were taught novel words using a modified version of the Intermodal Preferential Looking Paradigm. Seventeen children (range 7–10 years) returned to participate in a longitudinal follow-up. Novel word learning in infancy uniquely accounted for 22% of the variance in childhood receptive vocabulary but did not predict later childhood visuospatial ability or non-verbal IQ. These results suggest that the ability to associate novel sound patterns to novel objects, an index of the process of word learning, may be especially important for long-term language mastery.

Forming associations between language and sensorimotor traces during novel word learning

2016 ◽  
Vol 9 (1) ◽  
pp. 156-171 ◽  
Author(s):  
BIRGIT ÖTTL ◽  
CAROLIN DUDSCHIG ◽  
BARBARA KAUP
Keyword(s):  
Language Learning ◽  
Word Learning ◽  
Arm Movement ◽  
Learning Phase ◽  
Movement Direction ◽  
Lower Visual Field ◽  
Adult Participants ◽  
Novel Objects ◽  
Multisensory Environment ◽  
Novel Word Learning

abstractEmbodied models of language comprehension are based on the assumption that words become associated with sensorimotor experiences during initial word learning. To test this hypothesis, adult participants learned artificial words as labels for novel objects in a multisensory environment. In a word learning phase, novel objects were located in the participant’s upper or lower visual field and participants learned the objects’ names by interacting with them. In a test phase, participants responded to the color of the words with either an upwards or a downwards directed arm movement in a Stroop-like paradigm. Responses were fastest when the movement direction was compatible with the word’s referent location (i.e., the location of the novel object in vertical space) during the learning phase. This finding suggests that sensorimotor experiences become associated with words during initial word learning. The results of the current study and implications for language learning are discussed.

Enhanced MRI Evaluation of Children with Sickle Cell Following Hematopoietic Stem Cell Transplantation

Blood ◽  
2015 ◽  
Vol 126 (23) ◽  
pp. 981-981
Author(s):  
Nancy S. Green ◽  
Monica Bhatia ◽  
Erica Griffin ◽  
Mahvish Qureshi ◽  
Courtney Briamonte ◽  
...  
Keyword(s):  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Parent Report ◽  
Self Report ◽  
Small Vessel ◽  
Hematopoietic Stem ◽  
Mri Scans ◽  
Clinical Mri

Abstract Introduction: Sickle cell disease (SCD) CNS vasculopathy (SCNSV) is a frequent indication for hematopoietic stem cell transplantation (HSCT). Untreated, SCNSV can be progressive and impair quality of life (QoL) and cognitive functioning. By clinical MRI/MRA assessment, HSCT is thought to halt progression of SCNSV. Quantitative analysis of T2-weighted FLAIR MRI for white matter hyperintensity (WMH) can provide a meaningful estimate of small vessel cerebrovascular burden. Adding WMH assessment, we asked whether HSCT for SCD halted long-term progression of SCNSV, including small vessel involvement, despite transplant-associated CNS risks. QoL assessment can track school functioning and physical, emotional and social functioning. Methods: This retrospective single site study compared MRI analyses pre-transplant to 1-7-years post-HSCT. Subject eligibility required availability of clinical MRI scans from within 2 months pre-HSCT and at 1-year intervals for at least one year post-HSCT. Interim scans performed for acute clinical indications were not included in the analysis. MRI scans were evaluated independent to the initial clinical read by one neuroradiologist, and via in-house developed software to quantitate WMH burden. QoL was completed by parent- and child-report pre-HSCT and annually thereafter using the Peds QL 4.0TM with scores 0-100; higher numbers reflected higher QoL. Results: 25 patients who received HSCT for SCD between 2003-2014 were evaluated. Median age at HSCT was 9.9 years (1.4-21.9); male:female 18:7; HbSS (17), HbSC (3), HbS-Bthalassemia (5). Donors were related (14) or unrelated (11). Stem cell sources were: related bone marrow (BM) (10), unrelated BM (5), related cord blood (CB) (3), unrelated CB (6), or related peripheral blood stem cells (1). Eight patients had CNS pathology as the indication for HSCT. Transplant complications were: PRES (2), stroke (1), graft failure (2), death (1). Duration of follow-up was: 1 yr (9), 2 yrs (10), >2 yrs (6). Only a minority of patients had normal pre-HSCT MRI (5) and normal MRA (11; 6 had 1-2 stenoses <2mm and were rated as ambiguous). At 1 to 7 yrs post-HSCT, 5 originally normal MRIs were unchanged, 15 MRIs were stable and 4 were improved at 1 year post-HSCT, without subsequent changes by clinical assessment. One MRI worsened due to peri-HSCT hemorrhagic stroke. MRAs were unchanged following HSCT. Preliminary analysis of 18 patients at pre-HSCT revealed that 5 did not have elevated WMH, while elevated WMH was detected in 13 patients. WMH remained stable in 16 of 18 patients over subsequent annual assessments. In the 2 patients with markedly elevated WMH pre-HSCT, values decreased at follow-up, corresponding to the resolution of acute or recent infarction. Overall pre-HSCT QoL by parent-report (N=19) was 65.3 (SD16.3); while child self-report (N=14) was 67.6, (SD13.1). After mean follow-up of 3 years, parent-report QoL improved to 78.8 (SD15.8), and self-report to 78.7 (SD15.2). Conclusions: Most children in this retrospective cohort had MRI abnormalities pre-HSCT, and all but 1 were stable or improved post-HSCT, despite PRES and other potential CNS complications. Pre-HSCT WMH appeared to be unchanged for most of these patients, while stroke-induced WMH appears to decrease over time, suggesting stable small vessel SCNSV following transplantation. Overall, by MRI/MRA and by preliminary WMH, HSCT appears to have stabilized large and small vessel SCNSV in all but 1 of 25 children. While only a modest number of patients were assessed, WMH was reproducible at multiple annual time points. Long-term parent and self-reported QoL indicated improvement from HSCT. Chronically transfused SCD patients could not be compared due to lack of annualized assessment. Future transplant protocols will include enhanced MRI-based tracking, in conjunction with QoL and neuropsychological assessments. These data could be useful for decision-making about SCD transplantation. Disclosures No relevant conflicts of interest to declare.

Novel Word Learning in Children With Hearing Impairment

1995 ◽  
Vol 38 (3) ◽  
pp. 630-642 ◽  
Author(s):  
Margie Gilbertson ◽  
Alan G. Kamhi
Keyword(s):  
Hearing Loss ◽  
Hearing Impairment ◽  
Word Learning ◽  
Phonological Processing ◽  
Normal Hearing ◽  
Receptive Vocabulary ◽  
Learning Ability ◽  
School Age Children ◽  
Learning Abilities ◽  
Novel Word Learning

This study examined novel word-learning abilities in young school-age children with mild-to-moderate hearing losses. We questioned whether degree of hearing loss or measures of language and phonological processing abilities were more likely to be related to novel word-learning ability. Subjects were 20 children with hearing impairment (M = 9:0) and 20 children with normal hearing (M = 6:5) matched for receptive vocabulary knowledge. Children were administered measures of language and phonological processing. The novel word-learning task consisted of an acquisition and retention phase in which children received a series of trials to learn to produce four novel words. Half of the children with hearing impairment performed comparably to the children with normal hearing on all of the measures obtained, whereas the other 10 children with hearing impairment performed more poorly than the higher functioning children with hearing impairment and all of the children with normal hearing on most of the measures of language, phonological processing, and novel word learning. Degree of hearing loss was not related to language or word-learning abilities. These findings suggest that the population of children with mild-to-moderate hearing loss may contain two distinct groups: a group of normally developing children who have a hearing loss and a group of children with language impairment who have a hearing loss. The implications of this categorization will be discussed.

scholarly journals Long-Term Impact of Malaria Chemoprophylaxis on Cognitive Abilities and Educational Attainment: Follow-Up of a Controlled Trial

2006 ◽  
Vol 1 (4) ◽  
pp. e19 ◽  
Author(s):  
Matthew C. H Jukes ◽  
Margaret Pinder ◽  
Elena L Grigorenko ◽  
Helen Baños Smith ◽  
Gijs Walraven ◽  
...  
Keyword(s):  
Educational Attainment ◽  
Cognitive Abilities ◽  
Controlled Trial ◽  
Malaria Chemoprophylaxis ◽  
Long Term Impact

Levels of Processing: Effects of Interference in Word Learning over Time

1987 ◽  
Vol 60 (2) ◽  
pp. 551-554
Author(s):  
Michael F. Shaughnessy ◽  
Katherine Divine ◽  
Kathleen Roche
Keyword(s):  
Word Learning ◽  
Retroactive Interference ◽  
Operational Definition ◽  
Levels Of Processing ◽  
Shallow Processing ◽  
Processing Effects ◽  
Over Time

Although much research has addressed the “levels-of-processing” perspective, critics continue to attack this formulation. The lack of an operational definition is frequently cited as a shortcoming of the perspective. Utilizing resistance to interference as a perspective from which to investigate “deep” and shallow” processing, an experiment was conducted with two follow-up tests to ascertain the effects of proactive and retroactive interference in immediate, intermediate, and long-term recall.

scholarly journals Evidence for Enhanced Long-term Memory in Professional Musicians and Its Contribution to Novel Word Learning

2020 ◽  
pp. 1-21
Author(s):  
Eva Dittinger ◽  
Betina Korka ◽  
Mireille Besson
Keyword(s):  
Word Learning ◽  
Semantic Processing ◽  
Long Term Memory ◽  
Transfer Effects ◽  
Music Training ◽  
Bottom Up ◽  
Term Memory ◽  
Novel Word Learning ◽  
Novel Words

Previous studies evidenced transfer effects from professional music training to novel word learning. However, it is unclear whether such an advantage is driven by cascading, bottom–up effects from better auditory perception and attention to semantic processing or by top–down influences from cognitive functions on perception. Moreover, the long-term effects of novel word learning remain an open issue. To address these questions, we used a word learning design, with four different sets of novel words, and we neutralized the potential perceptive and associative learning advantages in musicians. Under such conditions, we did not observe any advantage in musicians on the day of learning (Day 1), at neither a behavioral nor an electrophysiological level; this suggests that the previously reported advantages in musicians are likely to be related to bottom–up processes. Nevertheless, 1 month later (Day 30 [D30]) and for all types of novel words, the error increase from Day 1 to D30 was lower in musicians compared to nonmusicians. In addition, for the set of words that were perceptually difficult to discriminate, only musicians showed typical N400 effects over parietal sites on D30. These results demonstrate that music training improved long-term memory and that transfer effects from music training to word learning (i.e., semantic levels of speech processing) benefit from reinforced (long-term) memory functions. Finally, these findings highlight the positive impact of music training on the acquisition of foreign languages.

Therapy and prevention for mental health: What if mental diseases are mostly not brain disorders?

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis
Keyword(s):  
Mental Health ◽  
Mental Disease ◽  
Brain Disorders ◽  
Social Stressors ◽  
Labor Education ◽  
Mental Diseases ◽  
Long Term Follow Up ◽  
Political Decisions

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.

Brief summary of Kleť photographic search programme for minor planets

1999 ◽  
Vol 173 ◽  
pp. 189-192
Author(s):  
J. Tichá ◽  
M. Tichý ◽  
Z. Moravec
Keyword(s):  
Ccd Camera ◽  
Minor Planet ◽  
Minor Planets ◽  
Main Belt

AbstractA long-term photographic search programme for minor planets was begun at the Kleť Observatory at the end of seventies using a 0.63-m Maksutov telescope, but with insufficient respect for long-arc follow-up astrometry. More than two thousand provisional designations were given to new Kleť discoveries. Since 1993 targeted follow-up astrometry of Kleť candidates has been performed with a 0.57-m reflector equipped with a CCD camera, and reliable orbits for many previous Kleť discoveries have been determined. The photographic programme results in more than 350 numbered minor planets credited to Kleť, one of the world's most prolific discovery sites. Nearly 50 per cent of them were numbered as a consequence of CCD follow-up observations since 1994.This brief summary describes the results of this Kleť photographic minor planet survey between 1977 and 1996. The majority of the Kleť photographic discoveries are main belt asteroids, but two Amor type asteroids and one Trojan have been found.

Quantifying the Effects of Background Speech Babble on Preschool Children's Novel Word Learning in a Multisession Paradigm: A Preliminary Study

2020 ◽  
Vol 63 (1) ◽  
pp. 345-356
Author(s):  
Meital Avivi-Reich ◽  
Megan Y. Roberts ◽  
Tina M. Grieco-Calub
Keyword(s):  
Word Learning ◽  
Signal To Noise Ratio ◽  
Preschool Age ◽  
Exposure Condition ◽  
Signal To Noise ◽  
Verbal Recall ◽  
Referent Selection ◽  
Main Effect ◽  
Noise Ratio ◽  
Novel Word Learning

Purpose This study tested the effects of background speech babble on novel word learning in preschool children with a multisession paradigm. Method Eight 3-year-old children were exposed to a total of 8 novel word–object pairs across 2 story books presented digitally. Each story contained 4 novel consonant–vowel–consonant nonwords. Children were exposed to both stories, one in quiet and one in the presence of 4-talker babble presented at 0-dB signal-to-noise ratio. After each story, children's learning was tested with a referent selection task and a verbal recall (naming) task. Children were exposed to and tested on the novel word–object pairs on 5 separate days within a 2-week span. Results A significant main effect of session was found for both referent selection and verbal recall. There was also a significant main effect of exposure condition on referent selection performance, with more referents correctly selected for word–object pairs that were presented in quiet compared to pairs presented in speech babble. Finally, children's verbal recall of novel words was statistically better than baseline performance (i.e., 0%) on Sessions 3–5 for words exposed in quiet, but only on Session 5 for words exposed in speech babble. Conclusions These findings suggest that background speech babble at 0-dB signal-to-noise ratio disrupts novel word learning in preschool-age children. As a result, children may need more time and more exposures of a novel word before they can recognize or verbally recall it.

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