scholarly journals Respiratory Muscle Training in Patients With Moderate to Severe Myasthenia Gravis

1998 ◽  
Vol 25 (3) ◽  
pp. 236-241 ◽  
Author(s):  
Paltiel Weiner ◽  
Ditza Gross ◽  
Zeev Meiner ◽  
Rushrash Ganem ◽  
Margalit Weiner ◽  
...  
Keyword(s):  
Myasthenia Gravis ◽  
Respiratory Muscle ◽  
Respiratory Muscles ◽  
Complementary Therapy ◽  
Muscle Performance ◽  
Respiratory Muscle Training ◽  
Muscle Training ◽  
Group A ◽  
Group B ◽  
Respiratory Muscle Endurance

ABSTRACT:Background:Myasthenia gravis (MG) is a specific autoimmune disease characterized by weakness and fatigue. MG may affect also the respiratory muscles causing symptoms that may vary from dyspnea on severe exertion to dyspnea at rest. This study was undertaken in order to determine the effects of respiratory muscle training on respiratory muscle performance, spirometry data and the grade of dyspnea in patients with moderate to severe generalized MG.Methods:Eighteen patients with MG were studied and divided into 2 groups: Group A included 10 patients (3 males and 7 females aged 29-68) with moderate MG, and Group B that included 8 patients (5 males and 3 females aged 21-74) with severe MG. Patients in Group A received both inspiratory and expiratory muscle training for 1/2 h/day, 6 times a week, for 3 months, while patients in Group B followed the same protocol but had inspiratory muscle training only.Results:Mean PImax increased significantly from 56.6 ± 3.9 to 87.0 ± 5.8 cm H20 (p < 0.001) in Group A, and from 28.9 ± 5.9 to 45.5 ± 6.7 cm H20 (p < 0.005) in Group B. The mean PEmax also increased significantly in patients in Group A, but remained unchanged in the patients in Group B. The respiratory muscle endurance also increased significantly, from 47.9 ± 4.0 to 72.0 ± 4.2%, p < 0.001, in patients of Group A, and from 26.0 ± 2.9 to 43.4 ± 3.8, p < 0.001, in patients in Group B. The improved respiratory muscle performance was associated with a significant increase in the FEV, values, and in the FVC values, in patients of both groups. Mean dyspnea index score also increased significantly from 2.6 ± 0.8 to 3.6 ± 0.4 (p < 0.005) in Group A, and from 0.7 ± 0.2 to 2.0 ± 0.2 (p < 0.001) in Group B.Conclusions:Specific inspiratory threshold loading training alone, or combined with specific expiratory training, markedly improved respiratory muscle strength and endurance in patients with MG. This improvement in respiratory muscle performance was associated with improved lung function and decreased dyspnea. Respiratory muscle training may prove useful as a complementary therapy with the aim of reducing dyspnea symptoms, delay the breathing crisis and the need for mechanical ventilation in patients with MG.

scholarly journals Effect of respiratory muscle training on pulmonary function in preoperative preparation of tobacco smokers

2007 ◽  
Vol 22 (2) ◽  
pp. 98-104 ◽  
Author(s):  
Carrie Chueiri Ramos Galvan ◽  
Antônio José Maria Cataneo
Keyword(s):  
Pulmonary Function ◽  
Respiratory Muscle ◽  
Vital Capacity ◽  
Peak Flow ◽  
Respiratory Muscles ◽  
Forced Expiratory Volume ◽  
Respiratory Muscle Training ◽  
Specific Training ◽  
Muscle Training ◽  
Respiratory Exercises

PURPOSE: To evaluate the effect of utilization of a specific training program of respiratory muscles on pulmonary function in tobacco smokers. METHODS: Fifty asymptomatic tobacco smokers with age superior to 30 years were studied, at the moments: A0 - initial evaluation followed by protocol of respiratory exercises; A1 - reevaluation after 10 minutes of protocol application; and A2 - final reevaluation after 2 weeks of training utilizing the same protocol 3 times per week. The evaluation was realized through measures of maximum respiratory pressures (PImax and PEmax), respiratory peak flow (IPF and EPF), maximum voluntary ventilation (MVV), forced vital capacity (FVC) and forced expiratory volume at the 1st second (FEV1). RESULTS: There was no improvement from initial to final evaluation in FVC and FEV1. But there were significant increases in the variables IPF, EPF, MVV and PImax at evaluations A1 and A2. The PEmax variable increased only at evaluation A2. CONCLUSION: The application of the protocol of respiratory exercises with and without additional load in tobacco smokers produced immediate improvement in the performance of respiratory muscles, but this gain was more accentuated after 2 weeks of exercise.

scholarly journals Effect of high-intensity home-based respiratory muscle training on strength of respiratory muscles following a stroke: a protocol for a randomized controlled trial

2017 ◽  
Vol 21 (5) ◽  
pp. 372-377 ◽  
Author(s):  
Kênia Kiefer Parreiras De Menezes ◽  
Lucas Rodrigues Nascimento ◽  
Janaine Cunha Polese ◽  
Louise Ada ◽  
Luci Fuscaldi Teixeira-Salmela
Keyword(s):  
Randomized Controlled Trial ◽  
High Intensity ◽  
Respiratory Muscle ◽  
Controlled Trial ◽  
Respiratory Muscles ◽  
Respiratory Muscle Training ◽  
Muscle Training ◽  
Randomized Controlled ◽  
Home Based

scholarly journals Integrative respiratory and skeletal musculature training in patients with functional class II–IV chronic heart failure and low or intermediate left ventricular ejection fraction: Design and rationale

2020 ◽  
Vol 35 (2) ◽  
pp. 123-130
Author(s):  
J. L. Begrambekova ◽  
N. A. Karanadze ◽  
V. Yu. Mareev ◽  
E. A. Kolesnikova ◽  
Ya. A. Orlova
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Respiratory Muscle ◽  
Aerobic Training ◽  
Respiratory Muscles ◽  
Treadmill Walking ◽  
Respiratory Muscle Training ◽  
Left Ventricular Ejection ◽  
Control Group ◽  
Muscle Training

Respiratory system remodeling plays an important role in the progression of congestive heart failure (CHF). Decreased oxygenation of the respiratory muscles during intense physical exertion in patients with CHF may aggravate respiratory failure and provoke hyperactivation of the inspiratory metaborefl ex, thereby aggravating exercise intolerance due to a decrease in muscular system perfusion. Respiratory muscle training can minimize the eff ects of inspiration metaborefl ex activation and prolong the duration of exercise.Trial design. This is a prospective randomized trial with a sham control. The trial will include 40 adult patients of both genders with NYHA II-III CHF and with ejection fraction (EF) ≤ 49%. Patients will be randomized in a 1:1 ratio to either Active or Control group. Active group will receive four-week guided respiratory muscles training followed by 12-week guided aerobic training (treadmill walking). Control group will receive four-week sham respiratory muscles training (THRESHOLD® IMT breathing trainer with level slightly above 0), followed by 12 weeks guided aerobic training (treadmill walking). The primary aim is to compare the eff ect of diff erent training modalities on functional capacity (peak VO2 ). Secondary outcome measures include changes in respiratory muscle strength, serum biomarkers (NT-proBNP and ST2) and Angiotensin II. Health-related quality of life (MLwHFQ.23) and psycho-emotional state of patients also will be assessed.The study also planned an additional analysis with a suitable group of patients who were screened but refused to participate in the study.Conclusion. Heart failure patients often give up exercise due to symptoms of shortness of breath and muscle weakness. We suggest that the training technique based on the inclusion of respiratory muscle training as the fi rst stage of cardiac rehabilitation will positively aff ect the eff ectiveness of subsequent aerobic training in patients with heart failure, by reducing the activity of RAAS and SAS and increasing respiratory effi ciency. 

scholarly journals Different outcomes of pulmonary rehabilitation in patients with COPD with or without exacerbations

2005 ◽  
Vol 63 (3) ◽  
Author(s):  
G.G. Riario-Sforza ◽  
C. Incorvaia ◽  
F. Paterniti ◽  
N. Dugnani ◽  
M. Fumagalli
Keyword(s):  
Lung Function ◽  
Physical Performance ◽  
Pulmonary Rehabilitation ◽  
Respiratory Muscle ◽  
Hospital Setting ◽  
Favourable Outcome ◽  
Respiratory Muscle Training ◽  
Copd Exacerbations ◽  
Group A ◽  
Group B

Background. Pulmonary rehabilitation is recognised as an effective treatment in reducing disability and improving the quality of life in patients with COPD. We evaluated the effects of a course of pulmonary rehabilitation in improving the physical performance and lung function in patients with or without COPD exacerbations. Methods. 74 patients with COPD were enrolled, 37 (24 males and 13 females, mean age 74.6 years) without exacerbations (group A), and 37 (23 males, 14 females, mean age 73.9 years) with exacerbations (group B). The latter must have had the latest exacerbation at least one month before the inclusion. All patients underwent to a rehabilitation programme of 8 visits in 4 weeks in a day-hospital setting, with exercise training, respiratory muscle training and education on COPD. The changes in physical performance and lung function in respect to baseline were measured by a 6-minute walking test, using phethysmography, and by an analogic manometer measuring maximal inspiratory and expiratory pressures (MIP, MEP). Results. Patients of group A showed a mean increase in timed walk distance of 58.38 ± 57.46 m, compared to a mean increase of 31.38 ± 44.78 m in group B patients (p = 0.028). As to lung function, a mean increase of 178.92 ± 132.28 ml in FEV1 in group A versus 67.84 ± 102.04 ml in group B (p &lt; 0.0001) and a mean increase of 22.36 ± 25.06 cm H2O in MEP in group A versus 7.70 ± 12.28 cm H2O in group B (p = 0.002) was found. Conclusions. These findings indicate that patients with COPD with exacerbations achieve a less favourable outcome of pulmonary rehabilitation, with a significantly lower improvement of physical performance, respiratory muscle strength and lung function in respect to subjects without exacerbations.

Respiratory Muscle Endurance And Cardiovascular Response To Hyperpnoea After Respiratory Muscle Training In Hypoxia

2017 ◽  
Vol 49 (5S) ◽  
pp. 796
Author(s):  
Keisho Katayama ◽  
Erika Iwamoto ◽  
Toshiyuki Ohya ◽  
Kazushige Goto ◽  
Kenji Takao ◽  
...  
Keyword(s):  
Respiratory Muscle ◽  
Cardiovascular Response ◽  
Respiratory Muscle Training ◽  
Muscle Endurance ◽  
Muscle Training ◽  
Respiratory Muscle Endurance

scholarly journals Respiratory Muscle Training Improves Functional Outcomes and Reduces Fatigue in Patients with Myasthenia Gravis: A Single-Center Hospital-Based Prospective Study

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Che-Wei Hsu ◽  
Hui-Chen Lin ◽  
Wan-Chen Tsai ◽  
Yun-Ru Lai ◽  
Chih-Cheng Huang ◽  
...  
Keyword(s):  
Myasthenia Gravis ◽  
Functional Outcomes ◽  
Respiratory Muscle ◽  
Short Form ◽  
Outcome Measurement ◽  
Respiratory Muscle Training ◽  
Walking Distance ◽  
Control Group ◽  
Muscle Training ◽  
Home Based

Background. Myasthenia gravis (MG) is an immune-mediated disorder characterized by muscle fatigue and fluctuating weakness. Impairment in respiratory strength and endurance has been described in patients with generalized MG. We tested the hypothesis that respiratory muscle training (RMT) can improve functional outcomes and reduce fatigue in patients with MG. Methods. Eighteen patients with mild to moderate MG participated in this study. The training group underwent home-based RMT three times a week for 12 weeks. Sixteen patients with MG without RMT were enrolled as a disease control group. Lung function, autonomic testing, Multidimensional Fatigue Symptom Inventory-Short Form (MFSI-SF), and functional outcome measurement by using quantitative myasthenia gravis (QMG) score and myasthenia gravis composite (MGC) scale were measured before and after the 12-week RMT. Results. The 12-week RMT significantly increased forced vital capacity (FVC) from 77.9±12.6% to 83.8±17.7% (p=0.03), forced expiratory volume in one second (FEV1) from 75.2±18.3% to 83.3±19.0% (p=0.002), and 6-minute walking distance from 403.4±72.2 m to 466.1±68.5 m (p=0.003). The QMG score improved from 9.6±4.1 to 8.1±4.3 (p=0.04) and the MGC scale from 4.4±3.5 to 2.7±2.9 (p=0.02). The fatigue score (MFSI-SF) reduced from 17.1±14.7 to 13.5±16.9 (p=0.03). Conclusion. The home-based RMT is an effective pulmonary function training for MG patients. The RMT can not only improve short-term outcomes but also reduce fatigue in patients with mild to moderate generalized MG.

scholarly journals EFFECTS OF INDIVIDUALIZED TRAINING AND RESPIRATORY MUSCLE TRAINING IN IMPROVING SWIMMING PERFORMANCE AMONG COLLEGIATE SWIMMERS - AN EXPERIMENTAL STUDY

2021 ◽  
Vol 9 (Spl-1- GCSGD_2020) ◽  
pp. S125-S132
Author(s):  
Sivaguru Muthusamy ◽  
◽  
Ambusam Subramaniam ◽  
K. Balasubramanian ◽  
◽  
...  
Keyword(s):  
Respiratory Muscle ◽  
Perceived Exertion ◽  
Swimming Performance ◽  
Training Session ◽  
Respiratory Muscle Training ◽  
Repeated Measure ◽  
Muscle Training ◽  
Training Approach ◽  
Group A ◽  
Individualized Training

Previous researches have been conducted to determine the types of training to improve swimming performance. Nevertheless, no study has been done on the individualized training approach among swimmers. Hence, this study aimed (i) to examine the effects of respiratory muscle training on swimming performance (ii) to examine the effects of combined respiratory muscle training with individualized training on swimming performance, and (iii) to compare the differences between the isolated respiratory muscle training, combined intervention of respiratory muscle training with individualized training and usual training on swimming performance. For this, 45 collegiate swimmers with no previous injuries and swims regularly for at least 1 hour per week participated in the study. Participants were randomly assigned into three groups; Group A: Respiratory muscle training and Individualized Training, Group B: Respiratory muscle training alone, and Group C: Usual training session. The difference within the groups after four weeks of the intervention was analyzed using Paired T-test, while the differences between intervention groups were analyzed using repeated measure two-way ANOVA. Both the intervention groups (Group A and B) showed significant improvement after four weeks of intervention, whereas in group comparison, Group A showed tremendous improvement in swimming performance (F (17,238) = 8.385, p<0.05, np2 = 0.375). Thus, the current study has proven that the combination of respiratory muscle training with individualized training could further enhance the swimming performance in terms of heart rate, Vo2 max, stroke volume, perceived exertion, and SWOLF score. Future studies on athletic swimmers with a larger sample size are recommended to further examine the individualized training approach.

Sign in / Sign up

Export Citation Format

Share Document