Particle Counting and Detection
1968 ◽
Vol 26
◽
pp. 104-105
Keyword(s):
The limit of detection of viral particles with UV absorption is 1010 particles per milliliter and that of the routinely employed electron microscopy technique is 107 to 108 particles per milliliter so that low titre virus preparations such as hepatitis serum must be concentrated severalfold if these physical methods are to be used.The sensitivity of the electron microscope can be increased if all the particles in a given volume of sample can be sedimented onto one microscope grid and a study of this has been made using polio virus which titred 4 X 1012 by light scattering and 6 X 1011 by sedimentation. The number of micrographs and the necessary magnification to detect 105 particles per milliliter were calculated.
2019 ◽
Vol 23
(3)
◽
pp. 337-342
◽
1978 ◽
Vol 36
(2)
◽
pp. 158-159
Keyword(s):
1983 ◽
Vol 41
◽
pp. 28-29
1969 ◽
Vol 27
◽
pp. 12-13
1967 ◽
Vol 25
◽
pp. 310-311
1969 ◽
Vol 27
◽
pp. 422-423
◽
1974 ◽
Vol 32
◽
pp. 410-411
1973 ◽
Vol 31
◽
pp. 8-9
◽
1970 ◽
Vol 28
◽
pp. 156-157