scholarly journals Municipal drinking water and cryptosporidiosis among persons with AIDS in Los Angeles County

1994 ◽  
Vol 113 (2) ◽  
pp. 313-320 ◽  
Author(s):  
F. Sorvillo ◽  
L. E. Lieb ◽  
B. Nahlen ◽  
J. Miller ◽  
L. Mascola ◽  
...  

SUMMARYTo assess unfiltered drinking water as a source of cryptosporidium infection in patients with the acquired immunodeficiency syndrome (AIDS) the prevalence of cryptosporidiosis among persons with AIDS in Los Angeles County was assessed by water service area. One water distributor, serving approximately 60% of the county's residents (area B), has consistently employed filtration. The other company, which serves the remainder of the county (area A), did not institute nitration until mid-December 1986. This difference provided a ‘natural experiment ’ in which to assess the effect of municipal water filtration on the level of cryptosporidiosis among persons with AIDS. The prevalence of cryptosporidiosis among AIDS patients was compared for the two water service areas for the time period (1983–6) preceding the implementation of filtration in area A. From 1983 to 1986 the age-standardized prevalence of cryptosporidiosis among AIDS patients was 32% lower in area A (4·2%), which received unfiltered water, than in area B (6·2%). Following addition of filtration in area A, the prevalence of cryptosporidiosis among AIDS patients decreased by 20%; however, a decline, of 47%, was also observed in area B. The similar baseline levels of cryptosporidiosis and the corresponding post-filtration decline in both areas suggest that filtration had no effect on levels of cryptosporidiosis among persons with AIDS. Thus it does not appear that municipal drinking water is an important risk factor for cryptosporidiosis in AIDS patients residing in Los Angeles County.

1995 ◽  
Vol 53 (6) ◽  
pp. 656-659 ◽  
Author(s):  
Frank J. Sorvillo ◽  
James Seidel ◽  
Loren E. Lieb ◽  
Lawrence R. Ash ◽  
Jerrold Turner ◽  
...  

2011 ◽  
Vol 15 (02) ◽  
pp. 245-248
Author(s):  
Flavia Silveira ◽  
Gabriel Bijos Faidiga ◽  
Tassiana do Lago ◽  
Camila Carrara Yassuda ◽  
Eduardo Tanaka Massuda ◽  
...  

Summary Introduction: Fungal mastoidits by Aspergillus fumigates predominantly occurs in immunosuppressed patients. Diagnosis is usually hard and disease is potentially fatal. Treatment is comprised of antifungal therapy, surgical debridement and immunosuppression correction. Case Report: This article reports a case of fungal mastoiditis in a patient with acquired immunodeficiency syndrome (AIDS). The treatment performed was that of surgery associated with antifungal therapy. The patient's facial nerve was not affected, what does not exclude potentially fatal complications of mastoiditis.


PEDIATRICS ◽  
1993 ◽  
Vol 91 (6) ◽  
pp. 1217-1217
Author(s):  
U. BLECKER ◽  
K. KEYMOLEN ◽  
H. SOUAYAH ◽  
J. LEVY ◽  
Y. VANDENPLAS

To the Editor.— It has been demonstrated that the presence of Helicobacter pylori-associated gastritis is rare in adults with acquired immunodeficiency syndrome (AIDS).1 To investigate the prevalence of H pylori infection in pediatric AIDS patients, we examined 19 children, aged 1 to 14 years (mean age 5 years 11 months), of mainly central African ethnic origin. They were compared to an asymptomatic control population of comparable age (n = 52; mean age = 5 years, 10 months) and ethnic origin.


2007 ◽  
Vol 49 (2) ◽  
pp. 113-116 ◽  
Author(s):  
Carlos José Dornas Gonçalves Barbosa ◽  
Rodrigo Juliano Molina ◽  
Murilo Barcelos de Souza ◽  
Ana Cristina A. Silva ◽  
Adilha Rua Micheletti ◽  
...  

This report describes two patients who presented acute disseminated and severe toxoplasmosis as the first opportunistic disease related to acquired immunodeficiency syndrome. At admission, clinical and laboratory findings were similar to sepsis or septic shock and a fast evolutive course to death occurred in both cases. At necropsy, an inflammatory reaction and presence of a great number of Toxoplasma gondii cysts and tachyzoites were observed in most organs examined.


Blood ◽  
1990 ◽  
Vol 76 (8) ◽  
pp. 1490-1493 ◽  
Author(s):  
H Schuitemaker ◽  
NA Kootstra ◽  
MH van Oers ◽  
R van Lambalgen ◽  
M Tersmette ◽  
...  

Abstract Myelosuppression is a major symptom in the acquired immunodeficiency syndrome (AIDS). Moreover zidovudine, an anti-retroviral drug used to treat AIDS patients has myelosuppressive side effects. Therefore treatment with IL-3, a multi-lineage hemopoietic growth factor may be beneficial for zidovudine-treated individuals. In this study we examined the effect of IL-3 on human immunodeficiency virus (HIV) expression. The proliferative response to rIL-3 and the effects on the replication of the monocytotropic HIV variant, HTLV-III Ba-L, in the absence or presence of the anti-retroviral drug zidovudine was studied in purified human peripheral blood monocytes. Zidovudine concentrations sufficient for complete inhibition of HIV replication did not affect rIL-3 induced monocyte proliferation. Although rIL-3, like rGM-CSF, was able to augment HIV expression in monocytes, it did not interfere with the anti-retroviral activity of zidovudine. These data indicate that rIL-3 is a potential candidate for use in myelosupportive therapy in AIDS patients treated with anti-retroviral drugs.


1997 ◽  
Vol 39 (4) ◽  
pp. 213-216 ◽  
Author(s):  
Jorge CASSEB ◽  
Adele CATERINO-DE ARAUJO ◽  
Marisa A. HONG ◽  
Simone SALOMÃO ◽  
Dana GALLO ◽  
...  

Human immunodeficiency virus (HIV-1)-infected subjects with acquired immunodeficiency syndrome (AIDS) are often infected with multiple pathogens. In particular, HTLV-I and HTLV-II infections have been found more frequently in AIDS patients than in asymptomatic individuals in Europe and Japan. We carried out a serosurvey among asymptomatic HIV-1-infected subjects in São Paulo, Brazil and compared our results with those of other investigators. In this study, we found HTLV infection in 1.5% of 266 asymptomatic and 14% of 28 AIDS patients. Epidemiological data obtained from patients pointed out the use of intravenous drugs as the principal risk factor for acquiring retroviruses. In conclusion, our results are in accordance with other studies done in Brazil and elsewhere where the principal risk group for HIV/HTLV-I/II coinfection was IDU


2009 ◽  
Vol 20 (8) ◽  
pp. 582-584 ◽  
Author(s):  
S Shushan ◽  
U Cinamon ◽  
D Levy ◽  
M Sokolov ◽  
Y Roth

With improved survival, more AIDS patients, especially heavy smokers and alcohol abusers, may be confronted with laryngeal squamous cell carcinoma. Since curative treatment may require aggressive combined therapy, these patients, often suffering from immunosupression and poor general condition, present unique therapeutic challenges. The objective of the study was to describe treatment dilemmas. This case report presents a detailed description of an AIDS patient with carcinoma of the larynx. A patient with T3N0M0 laryngeal carcinoma and AIDS underwent tracheotomy and biopsy, followed by severe neck and pulmonary infection. After convalescence, radiotherapy was administered, with no evidence of a disease during a 3.5-year follow-up. During his remaining life, the patient developed severe psychoaffective disorder, his immune state deteriorated until he demised from sepsis. In conclusion, patients with HIV infection, especially having a history of tobacco or alcohol abuse, should be carefully examined for head and neck carcinoma that is likely to be more aggressive. Following surgery, AIDS patients may have worse wound healing and a greater tendency to contract infections. Radiotherapy and especially chemotherapy may cause life-threatening complications. Although early detection may increase survival, curative treatment should involve many disciplines and extra caution.


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