Factors predicting discharge of Huntington's disease patients from a neuropsychiatry unit

2010 ◽  
Vol 22 (3) ◽  
pp. 489-492 ◽  
Author(s):  
Akshya Vasudev ◽  
Tracy Palmer ◽  
Alan Thomas ◽  
David Burn ◽  
William Barker

ABSTRACTBackground: We explored phenotypic parameters of people with Huntington's disease who had been admitted to a psychiatric unit and then discharged, with a view to determining prognostic factors for discharge to higher levels of care.Methods: A cross-sectional study was carried out on 19 patients admitted to a psychiatric unit with Huntington's disease. Data on the Unified Huntington's Disease Rating Scale (UHDRS) of behavior and function, global assessment of presence of depression and dementia as well as discharge outcomes were collated. Appropriate parametric and non-parametric statistical tests were applied.Results: Fourteen patients were discharged to accommodation with the same level of care versus five who were discharged to a higher level of care. Having poor functioning in terms of activities of daily living predicted discharge to an increased level of care. Being depressed or having dementia did not forecast poor outcome. The total duration of admission was not related to UHDRS parameters.Conclusions: Poor functioning on admission independently predicts the need for higher levels of care for patients who are admitted to a neuropsychiatric ward.

1993 ◽  
Vol 6 (1) ◽  
pp. 43-47 ◽  
Author(s):  
R. S. Shiwach ◽  
V. Patel

We describe a cross-sectional study of aggressive behaviour in a sample of patients suffering from Huntington's disease in a residential nursing home. Data were obtained using the RAGE, a behaviourally oriented rating scale for measuring aggressive behaviour in cognitively impaired patients. Nursing staff rated 27 patients after a 3 day observation period. A third of the sample were rated to be at least mildly aggressive; the frequencies of some specific types of aggressive behaviour were high. In contrast, the frequency of injuries sustained and the use of restraints and medication for aggressive behaviour were low. Aggressive behaviour was found to be significantly related to the degree of functional impairment. These data are compared with those reported in a study using the RAGE to assess aggressive behaviour in a sample of elderly patients with dementia.


2017 ◽  
Vol 79 (1-2) ◽  
pp. 13-20 ◽  
Author(s):  
Mário Sousa ◽  
Fradique Moreira ◽  
Joana Jesus-Ribeiro ◽  
Inês Marques ◽  
Flávia Cunha ◽  
...  

2018 ◽  
Vol 46 ◽  
pp. e33
Author(s):  
W. Liu ◽  
J. Yang ◽  
K. Chen ◽  
Q. Wei ◽  
J.-M. Burgunder ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Shu Cui ◽  
Fangshuo Cheng ◽  
Qiuyu Yuan ◽  
Ling Zhang ◽  
Lei Wang ◽  
...  

Introduction: China has 1.18 million methamphetamine abusers. Among the illegal drugs in China, methamphetamine has the highest abuse rate. Although previous studies have indicated a positive relationship between alexithymia and declining social support, the incidence of alexithymia, the total duration of methamphetamine dependence, social support, and the relationships between them among methamphetamine-dependent patients in the Chinese population have been rarely reported.Methods: A total of 113 methamphetamine-dependent patients (all male, mean age 30.45 ± 3.81 years) were enrolled in this cross-sectional study. General demographic data were collected. Alexithymia and social support were measured by Toronto Alexithymia Scale and Social Support Rating Scale.Results: Duration of methamphetamine use among Chinese male methamphetamine-dependent patients in compulsory detoxification was 8.01 ± 3.80 years on average, 23% (26/113) methamphetamine-dependent patients were considered to have alexithymia personality traits. Compared with short-duration methamphetamine-dependent patients (≤8 years), long-duration methamphetamine-dependent patients (> 8 years) were characterized by older age, higher incidence of alexithymia, less subjective social support and support availability, and greater difficulty in identifying feelings. The results of correlation analysis and multiple linear regression analysis indicated that the total duration of methamphetamine use was positively correlated with difficulty in identifying feelings, but negatively correlated with subjective social support.Conclusions: This study provides support for an association between the duration of methamphetamine use and difficulty in identifying feelings or subjective social support. Although the causality is still unclear, this finding should be considered in the psychotherapy of methamphetamine rehabilitation.


2020 ◽  
Vol 9 (4) ◽  
pp. 325-334
Author(s):  
Aline Ferreira-Correia ◽  
Amanda Krause ◽  
David G. Anderson

Background: Huntington Disease-Like 2 (HDL2) is a rare autosomal dominant disorder caused by an abnormal CAG/CTG triplet repeat expansion on chromosome 16q24. The symptoms of progressive decline in motor, cognitive and psychiatric functioning are similar to those of Huntington’s disease (HD). The psychiatric features of the HDL2 have been poorly characterized. Objective: To describe the neuropsychiatric features of HDL2 and compare them with those of HD. Methods: A blinded cross-sectional design was used to compare the behavioural component of the Unified Huntington’s Disease Rating Scale (UHDRS) in participants with HDL2 (n = 15) and HD (n = 13) with African ancestry. Results: HDL2 patients presented with psychiatric symptoms involving mood disturbances and behavioural changes that were not significantly different from those in the HD group. Duration of disease and motor performance correlated (p < 0.001) with the Functional Capacity score and the Independence score of the UHDRS. HD patients reported movement dysfunction as the first symptom more frequently than HDL2 Patients (p < 0.001). Conclusion: The psychiatric phenotype of HDL2 is similar to that of HD and linked to motor decline and disease duration. Psychiatric symptoms seem more severe for HDL2 patients in the early stages of the disease.


2021 ◽  
pp. 1-11
Author(s):  
Kristel Kalkers ◽  
Jos M.G.A. Schols ◽  
Erik W. van Zwet ◽  
Raymund A.C. Roos

Background: Falls are common in Huntington’s disease (HD), which can have serious consequences and may therefore lead to fear of falling (FoF). There is little knowledge about falls or FoF in individuals with HD or about formal and informal caregivers’ fear about falls in individuals with HD. Objective: To explore prevalence of falls, FoF and fall preventive measures both those applied and those not included in managing falls in individuals with HD and their formal and informal caregivers, and to identify the relationship between FoF and, anxiety, awareness and cognitive functioning respectively. Methods: In a multi-center observational cross-sectional study, care-independent and -dependent individuals with HD and their formal and informal caregivers were recruited from six Dutch nursing homes specialized in HD. The participants were assessed by means of questionnaires enquiring about falls, FoF, awareness of fall risk, cognition, anxiety and fall preventive measures. Results: For all included 158 individuals with HD, the fall prevalence over the last 30 days was 28.8%. The prevalence of FoF in individuals with HD, formal caregivers and informal caregivers was 47.6%, 25.6%, and 63.5%, respectively, for care-independent individuals with HD and 46.9%, 26.3%, and 62.0%, respectively, for care-dependent individuals with HD. Anticipatory awareness of fall risks and gender are predictors of FoF in care-independent individuals with HD, though not in the care-dependent group. A combination of fall preventive measures is used in most individuals with HD. Conclusion: Fall prevalence is high and FoF is common in individuals with HD and their caregivers. Gender and anticipatory awareness are risk factors for FoF. In addition to the use of individual multifactorial fall prevention strategies, it is important to support both formal and informal caregivers in coping with falls


2020 ◽  
Vol 12 (1) ◽  
pp. 7-13
Author(s):  
Akhmad yanuar Fahmi ◽  
Dayu Inggida Sharon ◽  
Riska Nurfadhilah ◽  
Soekardjo

Background: Life in a Prison or a closed Penitentiary always attracts researchers or academics to discuss because of the many problems of life, how to adapt, and how to socialize with a new life in prison. The problems often faced are Self-acceptance and anxiety. Self-acceptance is someone's satisfaction with sleep, so that someone does not show feelings of fatigue, lethargy and anxiety. Poor Self-acceptance can result in decreased activity of the prefrontal cortex which plays an important role in regulating emotions, one of which is anxiety. Aim: The purpose of this study is to determine the relationship between Self-acceptance and anxiety levels in women-assisted residents in correctional institutions. Method: This type of research is Cross Sectional with a sample of 59 respondents with purposive sampling technique. Data collection using the questionnaire sheet Pittsbrugh Self-acceptance Index and Hamilton Anxiety Rating Scale, with Chi Square statistical tests using manual calculations with SPSS Aplication. Results: The results showed 50 respondents (85%) had poor Self-acceptance and 36 respondents (62%) had mild anxiety. significance level or α = 0.05 is obtained Pvalue = 0.015 so that Pvalue <value α or 0.015 <0.05. Means there is a relationship between the level of Self-acceptance with the level of anxiety in women fostered citizens in prison. Conclusion: Good Self-acceptance makes the anxiety level low or doesn't experience anxiety. Conversely, if the quality of sleep is poor, the level of anxiety experienced by women-assisted citizens is being experienced even with severe anxiety.


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