Spontaneous aortic thrombosis in neonates: a case report and review of literature

2020 ◽  
Vol 30 (1) ◽  
pp. 95-99 ◽  
Author(s):  
John P. Mulcaire-Jones ◽  
David K. Bailly ◽  
Deborah U. Frank ◽  
Anupam R. Verma ◽  
Bradley J. Barney ◽  
...  
Keyword(s):  
Umbilical Artery ◽  
Treatment Method ◽  
Rare Occurrence ◽  
Review Of Literature ◽  
Review Of The Literature ◽  
Lower Odds ◽  
Aortic Thrombosis ◽  
Reference Treatment ◽  
Life Threatening ◽  
Management Recommendations

AbstractNeonatal aortic thrombosis is a rare occurrence but can be life-threatening. Most aortic thrombosis in neonates is related to umbilical artery catheters. A case of a neonate with a spontaneous aortic thrombosis is described here along with a comprehensive review of the literature for cases of neonatal aortic thrombosis not related to any intravascular device or procedure. The aetiologies of these spontaneous thromboses and the relevance of hypercoagulable disorders are discussed. The cases were analysed for odds of death by treatment method adjusted for era. The reference treatment method was thrombolysis and anticoagulation. No other treatment modality had significantly lower odds than the reference. Surgery alone had higher odds for death than the reference, but this may be confounded by severity of case. The management recommendations for clinicians encountering neonates with spontaneous neonatal aortic thrombosis are discussed.

Neonatal ascending aortic thrombus: successful medical treatment

2012 ◽  
Vol 23 (4) ◽  
pp. 610-612
Author(s):  
Roberto Gallotti ◽  
Cheryl E. Cammock ◽  
Natalia Dixon ◽  
Yoshio Ootaki
Keyword(s):  
Thrombolytic Therapy ◽  
Arterial Thrombosis ◽  
Umbilical Artery ◽  
Ascending Aorta ◽  
Significant Morbidity ◽  
Aortic Thrombosis ◽  
Common Location ◽  
Aortic Thrombus ◽  
Threatening Condition ◽  
Life Threatening

AbstractNeonatal aortic thrombosis is a potentially life-threatening condition with significant morbidity and mortality if undiagnosed and untreated. The most common location of arterial thrombosis in neonates is in the abdominal aorta and is associated with umbilical artery catheterisation. There are only a few previous reports of thrombosis in the ascending aorta. We describe a case of ascending aortic thrombosis in a neonate who underwent successful thrombolytic therapy.

scholarly journals Granulomatous Periorificial Dermatitis in an Adult: A case report with review of literature

2020 ◽  
Vol 20 (1) ◽  
pp. 100
Author(s):  
Al-Mutasim Al-Qassabi ◽  
Khalid Al-Busaidi ◽  
Kaouthar Al Baccouche ◽  
Abla Al Ismaili
Keyword(s):  
Case Report ◽  
Rare Occurrence ◽  
Review Of Literature ◽  
Review Of The Literature ◽  
Prepubertal Children ◽  
Dermatology Clinic ◽  
Papular Eruption ◽  
Topical Metronidazole ◽  
Perioral Dermatitis ◽  
The Face

Granulomatous periorificial dermatitis (GPD) is a benign, self-limiting eruption that is considered a clinical variant of periorificial dermatitis, also known as perioral dermatitis. It presents primarily in prepubertal children as monomorphic scaly papules over perioral, paranasal and periorbital areas of the face with rare occurrence in adults. We report a 36-year-old Omani male patient who presented to the Dermatology Clinic at Bahla Polyclinic, Bahla, Oman, in 2018 with a papular eruption over his face for the previous six months. Based on clinical and histopathological findings the patient was diagnosed with GPD with sarcoid-like histology. He was treated effectively with oral doxycycline and topical metronidazole. This report provides a review of the literature on GPD and summarises all reported cases in adults to date.Keywords: Perioral Dermatitis; Dermatitis; Granulomas; Case Report; Oman.

scholarly journals Bucco-lingual Impaction of Mandibular Second Premolar: Case Report and Review of Literature

2020 ◽  
Vol 1 (6) ◽  
Author(s):  
Madiraju Guna Shekhar ◽  
Pavagada S. Pavankumar ◽  
Veeriah J. Chowdary ◽  
Anil B. Shivappa
Keyword(s):  
Case Report ◽  
Treatment Planning ◽  
Rare Occurrence ◽  
Review Of Literature ◽  
Review Of The Literature ◽  
Permanent Molars

Mandibular second premolars rank third after third permanent molars and maxillary permanent canines in frequency of impaction. They are found impacted at different angulations and positions and should be carefully evaluated radiographically during treatment planning. This article reports a rare occurrence of bucco-lingually impacted mandibular second premolar treated with odontectomy and odontotomy with a brief review of the literature.

scholarly journals Second Trimester Cervical Ectopic Pregnancy and Hemorrhage: A Case Report and Review of the Literature

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Jessian L. Munoz ◽  
Amanda Kalan ◽  
Katherine Singh
Keyword(s):  
United States ◽  
Case Report ◽  
The United States ◽  
Management Approach ◽  
Second Trimester ◽  
Rare Occurrence ◽  
Review Of The Literature ◽  
Life Threatening ◽  
Ectopic Pregnancies ◽  
Cervical Ectopic Pregnancy

Cervical ectopic pregnancies are a rare occurrence in the United States. Here we present the interdisciplinary and conservative management approach to a cervical ectopic at an advanced gestational age. In addition, we review the surgical management of hemorrhage from cervical ectopic pregnancies, which is often catastrophic and life-threatening.

Meconium peritonitis: review of literature and own clinical observations

2020 ◽  
Author(s):  
E.N. Glavatskaya , O.V. Pribushenya , N.A. Venchikova
Keyword(s):  
Prenatal Diagnosis ◽  
Premature Birth ◽  
Surgical Care ◽  
Intestinal Wall ◽  
Meconium Peritonitis ◽  
Review Of Literature ◽  
Review Of The Literature ◽  
Clinical Observations ◽  
Loop Expansion ◽  
The Impact

Two clinical cases of meconium peritonitis in the fetuses are presented. The diagnosis was made prenatally at 30+5 and 20+1 weeks of gestation. The main ultrasound signs were ascites, loop expansion and thickening of the intestinal wall, peritoneal calcifications, meconium pseudocysts. In one case, pregnancy was complicated by polyhydramnios. In both cases, the pregnancy ended in premature birth, followed by surgical treatment during the first days of life. A review of the literature on the topic are discussed the etiology, the spectrum and frequency of ultrasound signs suggesting this condition in the fetus, the effectiveness of prenatal diagnosis, the prognosis for the life and health of the newborn, as well as the impact of the quality and timeliness of the prenatal diagnosis on the management of pregnancy and timeliness of surgical care for the newborn.

scholarly journals Prevention and management of major complications in percutaneous endoscopic gastrostomy

2021 ◽  
Vol 8 (1) ◽  
pp. e000628
Author(s):  
Kurt Boeykens ◽  
Ivo Duysburgh
Keyword(s):  
Clinical Practice ◽  
Abdominal Wall ◽  
Percutaneous Endoscopic Gastrostomy ◽  
Early Recognition ◽  
Endoscopic Technique ◽  
Abdominal Wound ◽  
Review Of The Literature ◽  
Endoscopic Gastrostomy ◽  
Major Complications ◽  
Life Threatening

BackgroundPercutaneousendoscopic gastrostomy is a commonly used endoscopic technique where a tube isplaced through the abdominal wall mainly to administer fluids, drugs and/orenteral nutrition. Several placement techniques are described in the literaturewith the ‘pull’ technique (Ponsky-Gardener) as the most popular one.Independent of the method used, placement includes a ‘blind’ perforation of thestomach through a small acute surgical abdominal wound. It is a generally safetechnique with only few major complications. Nevertheless these complicationscan be sometimes life-threatening or generate serious morbidity.MethodAnarrative review of the literature of major complications in percutaneousendoscopic gastrostomy.ResultsThis review was written from a clinical viewpoint focussing on prevention andmanagement of major complications and documentedscientific evidence with real cases from more than 20 years of clinical practice.ConclusionsMajorcomplications are rare but prevention, early recognition and popper management areimportant.

scholarly journals A Review of Biophysiological and Biochemical Indicators of Stress for Connected and Preventive Healthcare

Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 556
Author(s):  
Talha Iqbal ◽  
Adnan Elahi ◽  
Pau Redon ◽  
Patricia Vazquez ◽  
William Wijns ◽  
...  
Keyword(s):  
Cardiovascular Events ◽  
Medical Conditions ◽  
Review Of The Literature ◽  
Stress Monitoring ◽  
Preventive Healthcare ◽  
Connected Health ◽  
Root Cause ◽  
Chemical Indicators ◽  
Life Threatening ◽  
Assessment Of Stress

Stress is a known contributor to several life-threatening medical conditions and a risk factor for triggering acute cardiovascular events, as well as a root cause of several social problems. The burden of stress is increasing globally and, with that, is the interest in developing effective stress-monitoring solutions for preventive and connected health, particularly with the help of wearable sensing technologies. The recent development of miniaturized and flexible biosensors has enabled the development of connected wearable solutions to monitor stress and intervene in time to prevent the progression of stress-induced medical conditions. This paper presents a review of the literature on different physiological and chemical indicators of stress, which are commonly used for quantitative assessment of stress, and the associated sensing technologies.

scholarly journals Medical Adjuvants in the Treatment of Surgically Refractory Arteriovenous Malformations of the Head and Face: Case Report and Review of Literature

2021 ◽  
pp. 1-7
Author(s):  
Vaidya Govindarajan ◽  
Joshua D. Burks ◽  
Evan M. Luther ◽  
John W. Thompson ◽  
Robert M. Starke
Keyword(s):  
Arteriovenous Malformations ◽  
Mtor Inhibitors ◽  
Molecular Target ◽  
Review Of Literature ◽  
Review Of The Literature ◽  
Early Results ◽  
Number Of Patients ◽  
Initiation Of Therapy ◽  
The Brain ◽  
Radiographic Improvement

<b><i>Background:</i></b> Arteriovenous malformations (AVMs) of the brain and face present unique challenges for clinicians. Cerebral AVMs may induce hemorrhage or form aneurysms, while facial AVMs can cause significant disfigurement and pain. Moreover, facial AVMs often draw blood supply from arteries providing critical blood flow to other important structures of the head which may make them impossible to treat curatively. Medical adjuvants may be an important consideration in the management of these patients. <b><i>Summary:</i></b> We conducted a systematic review of the literature to identify other instances of molecular target of rapamycin (mTOR) inhibitors used as medical adjuvants for the treatment of cranial and facial AVMs. We also present 2 cases from our own institution where patients were treated with partial embolization, followed by adjuvant therapy with rapamycin. After screening a total of 75 articles, 7 were identified which described use of rapamycin in the treatment of inoperable cranial or facial AVM. In total, 21 cases were reviewed. The median treatment duration was 12 months (3–24.5 months), and the highest recorded dose was 3.5 mg/m<sup>2</sup>. 76.2% of patients demonstrated at least a partial response to rapamycin therapy. In 2 patients treated at our institution, symptomatic and radiographic improvement were noted 6 months after initiation of therapy. <b><i>Key Messages:</i></b> Early results have been encouraging in a small number of patients with inoperable AVM of the head and face treated with mTOR inhibitors. Further study of medical adjuvants such as rapamycin may be worthwhile.

scholarly journals Neonatal thoracoabdominal aortic thrombosis associated with the umbilical artery catheter: Successful management by transaortic thrombectomy

1986 ◽  
Vol 4 (2) ◽  
pp. 119-123 ◽  
Author(s):  
Peter D. Himmel ◽  
David S. Summer ◽  
Chalermlarp Mongkolsmai ◽  
Narinder Khanna
Keyword(s):  
Umbilical Artery ◽  
Successful Management ◽  
Aortic Thrombosis

scholarly journals Impact of COVID-19 on management of urogynaecology patients: a rapid review of the literature

2021 ◽  
Author(s):  
Jemina Loganathan ◽  
◽  
Stergios K. Doumouchtsis
Keyword(s):  
Evidence Synthesis ◽  
Horizontal Transmission ◽  
Rapid Review ◽  
Review Of The Literature ◽  
First Line ◽  
Face To Face ◽  
Manual Search ◽  
Guidance Documents ◽  
Management Recommendations

Abstract Introduction and hypothesis The coronavirus (COVID-19) pandemic has impacted health systems worldwide. There is a continuing need for clinicians to adapt practice to facilitate timely provision of medical care, whilst minimising horizontal transmission. Guidance and recommendations are increasingly available, and this rapid review aimed to provide a timely evidence synthesis on the current recommendations surrounding urogynaecological care. Methods We performed a literature review using PubMed/Medline, Embase and Cochrane and a manual search of national and international societies for management recommendations for urogynaecological patients during the COVID-19 pandemic. Results Nine guidance documents and 17 articles, including 10 reviews, were included. Virtual clinics are recommended for new and follow-up patients, to assess and initiate treatment, as well as triage patients who require face-to-face appointments. Outpatient investigations such as urodynamics and cystoscopy for benign indications can be deferred. Prolapse and continence surgery should be suspended, except in specific circumstances such as procidentia with upper tract complications and failed pessaries. There is no evidence to support a particular route of surgery, but recommendations are made to minimise COVID-19 transmission. Conclusions Urogynaecological patients face particular challenges owing to inherent vulnerabilities of these populations. Behavioural and medical therapies should be recommended as first line options and initiated via virtual or remote clinics, which are integral to management during the COVID-19 pandemic. Expanding the availability and accessibility of technology will be increasingly required. The majority of outpatient and inpatient procedures can be deferred, but the longer-term effects of such practices are unclear.

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