Mood Effects of Prefrontal Repetitive High-Frequency TMS in Healthy Volunteers

CNS Spectrums ◽  
1997 ◽  
Vol 2 (1) ◽  
pp. 53-68 ◽  
Author(s):  
Juliet Dearing Martin ◽  
Mark S. George ◽  
Benjamin D. Greenberg ◽  
Eric M. Wassermann ◽  
Thomas E. Schlaepfer ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
High Frequency ◽  
Mood Effects

Identification of Ulnar Artery Perforators Using Color Doppler Ultrasonography

2020 ◽  
Vol 36 (09) ◽  
pp. 667-672
Author(s):  
Megumi Ishiko ◽  
Koichi Yano ◽  
Ema Onode ◽  
Kiyohito Takamatsu
Keyword(s):  
Healthy Volunteers ◽  
High Frequency ◽  
Doppler Ultrasonography ◽  
Color Doppler ◽  
Ulnar Artery ◽  
Color Doppler Ultrasonography ◽  
Doppler Us ◽  
Frequency Transducer ◽  
High Frequency Transducer ◽  
Color Doppler Us

Abstract Background The ulnar artery perforator (UAP) flap, which is hairless, thin, and pliable, has been used for the reconstruction of soft tissues from the finger to the elbow. Preoperative planning is essential for a perforator flap surgery, and there are some tests to identify perforators. Color Doppler ultrasonography (US) with a high-frequency transducer helps in detecting decreased flow in smaller vessels, such as perforators. The purpose of this study was to determine the anatomical locations and origins of perforators arising from the ulnar artery using color Doppler US in healthy volunteers. Methods Forty forearms of 20 healthy volunteers were included in the study. Perforators arising from the ulnar artery, within 100 mm proximal to the pisiform, were investigated using color Doppler US with a high-frequency transducer. Results A total of 205 perforators were identified. On comparing the locations in each 20 mm section from the pisiform, the largest number of perforators was 58 (28%), within 20 mm proximal to the pisiform. The axial view demonstrated 44 (21%), 64 (31%), 32 (16%), and 65 (32%) perforators in the radial, ulnar, superficial, and deep aspects of the ulnar artery, respectively. Fifty-two and 28 essential perforators were supplied by the UAPs arising from the superficial and ulnar aspect within 20 mm proximal to the pisiform and between 21 and 40 mm proximal to the pisiform, respectively, while elevating the UAP flap. Conclusion This is the first study to assess the UAP using color Doppler US. Identification of UAP using color Doppler US can be used as a preoperative assessment for reliable elevation of a UAP flap.

SAFETY AND TOLERABILITY OF DIFFERENT PROTOCOLS OF HIGH-FREQUENCY RHYTHMIC TRANSCRANIAL MAGNETIC STIMULATION

2019 ◽  
pp. 26-37
Author(s):  
I.S. Bakulin ◽  
A.G. Poydasheva ◽  
D.Yu. Lagoda ◽  
K.M. Evdokimov ◽  
A.Kh. Zabirova ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Side Effects ◽  
Healthy Volunteers ◽  
Brain Stimulation ◽  
High Frequency ◽  
Magnetic Stimulation ◽  
Facial Muscle ◽  
Non Invasive ◽  
Mood Changes ◽  
Invasive Method

Rhythmic transcranial magnetic stimulation (rTMS) is a non-invasive method for brain stimulation, widely used in the treatment of various diseases and in research. In this regard, the problems of rTMS safety and tolerability are becoming especially relevant. Most studies describe only serious side effects of rTMS, which, in fact, are extremely rare. Other side effects which affect rTMS tolerability have been studied to a much lesser extent. The objective of the study is to examine all side effects which occur during and after rTMS sessions through prospective open observation of patients and healthy volunteers. Materials and Methods. Using standardized questionnaires, the authors analyzed the incidence of side effects during high-frequency rTMS and within 24 hours after the procedure in 51 patients with various diseases of the nervous system and in 11 healthy volunteers. Results. The overall frequency of side effects was 59.5 % during stimulation and 50.2 % within 24 hours after the procedure. Serious side effects, which led to cessation of stimulation were recorded in 5 % of cases (n=3). They were associated with the syncope development (n=1) and severe headache (n=2). During rTMS, the most frequent manifestations of side effects were drowsiness (30.4 %), headache (25.8 %) and facial muscle contraction (14.7 %). Twenty-four hours after rTMS the most common manifestations were headache (15.7 %), mood changes (10.2 %) and mental alertness problems (9.4 %). It was found out, that headache was statistically more frequent at the beginning of the rTMS course. During rTMS, headache is often not so heavy and it is usually throbbing. However, within 24 hours after stimulation headache is usually moderate, pressing or dull. Conclusion. The obtained data confirm the importance of using standardized questionnaires for studying side effects and developing methods for their prevention and relief. Keywords: transcranial magnetic stimulation, non-invasive brain stimulation, safety, tolerance, side effects, headache, syncope.

Difference of Human Kinetic Frequency on Mattress by Fourier Transform

2020 ◽  
Vol 2020 ◽  
Author(s):  
Hiroko Tadaura ◽  
Ryuho Kataoka
Keyword(s):  
Fourier Transform ◽  
Healthy Volunteers ◽  
High Frequency ◽  
High Hardness ◽  
Facility Management ◽  
The Body ◽  
Human Beings ◽  
Snowball Sampling ◽  
3D Motion Analysis ◽  
Human Kinetic

Background: The new science which examines the life in energy and frequency by quantum life science is noticed. Mattresses of various concepts are used on beds which are always installed in hospitals and facilities. It has been reported that human beings constantly roll over and vibrate in minute detail against the gravity, even at night, and it can be said that motion dynamics are necessary life activity as long as human beings live as living organisms. Therefore, it may be important as life observation to analyze not only physical aspects such as the body, bed and mattress, but also physical aspects such as kinematic and dynamic energy, force, speed and time, when examining human health and the medical treatment environment for life. However, few studies have examined the kinematic effects and differences of mattresses. The quality of a mattress affects the health of the patient or user using it in the short and long term. The choice of mattress and its cost are also important factors in hospital and facility management. In this study, we examined the differences of movement frequencies that human produce on the different mattresses.Methods: Healthy volunteers were recruited by a snowball sampling. The movement from the supine position to the sitting position on Air-based Mattress, Middle Hardees Urethane Mattress, and High hardness Urethane Mattress were repeated for three times. The three procedure was analyzed with a 12 segments model using a 3D motion analysis Move Tr 3D (Library©) under the 4 CCD cameras. The analysis of the velocity and acceleration data were performed by Fourier Transform (IDL). The sensory test for sleeping comfort revised was investigated after the third time. The mathematical expressions to be physically examined from the data of this study were also examined.Results: Five healthy volunteers (Medium age 31 years, Female) who received written consent to the study were investigated. Air mattress took longer time to be head up than both urethane mattresses. The velocity changes of both Medium Hardness and High Hardness Urethan mattresses were similar. Air mattress had a high frequency in the vicinity around 3 sec after the movement beginning. There was no difference in the frequency of the head acceleration between two mattresses and the high frequency was strong until coming to the head up.Conclusion: The difference in the human kinetic frequency using Fourier Transform suggests that there is a difference in the frequency produced by humans moving on different mattresses.

Effect of hot arm and foot bath on heart rate variability and blood pressure in healthy volunteers

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Samruddhi Chintaman Vyas ◽  
A. Mooventhan ◽  
N. K. Manjunath
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Healthy Volunteers ◽  
High Frequency ◽  
Low Frequency ◽  
Healthy Male ◽  
Before And After ◽  
Instantaneous Heart Rate ◽  
The Mean

AbstractBackgroundThough hot arm and foot bath (HAFB) is widely used, a precise physiological response is not reported. Hence, the present study was conducted to evaluate the effect of HAFB on heart rate variability (HRV) and blood pressure (BP) in healthy volunteers.Materials and MethodsSixteen healthy male volunteers’ aged 23.81 ± 5.27 (mean ± standard deviation) years were recruited. All the subjects underwent only one session of HAFB (104-degree Fahrenheit) for the duration of 20 min. Assessments such as Electrocardiography and BP were taken before and after the intervention.ResultsResults of this study showed a significant reduction in systolic-BP (SBP), diastolic-BP (DBP), mean arterial pressure (MAP), the mean of the intervals between adjacent QRS complexes or the instantaneous heart rate (RR interval), the number of interval differences of successive NN intervals greater than 50 ms (NN50), the proportion derived by dividing NN50 by the total number of NN intervals (pNN50), and high frequency (HF) band of HRV along with a significant increase in heart rate (HR), low-frequency (LF) band of HRV and LF/HF ratio compared to its baseline.ConclusionsResults of this study suggest that 20 min of HAFB produce a significant increase in HR and a significant reduction in SBP, DBP, and MAP while producing parasympathetic withdrawal.

scholarly journals Acoustic radiation force impulse (ARFI) shear wave elastography of the bowel wall in healthy volunteers and in ulcerative colitis

2019 ◽  
Vol 8 (4) ◽  
pp. 205846011984096
Author(s):  
Ruediger S Goertz ◽  
Christian Lueke ◽  
Barbara Schellhaas ◽  
Lukas Pfeifer ◽  
Dane Wildner ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
High Frequency ◽  
Bowel Wall ◽  
Acoustic Radiation ◽  
Radiation Force ◽  
Acoustic Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
High Frequency Ultrasound ◽  
Arfi Elastography ◽  
Frequency Ultrasound

Background Acoustic radiation force impulse (ARFI) elastography is a non-invasive, ultrasound-based approach of evaluation of tissue elasticity. It has not yet been systematically applied to the bowel wall. Purpose To perform ARFI elastography of the bowel wall in healthy volunteers and patients with ulcerative colitis (UC). Material and Methods A high-frequency ultrasound (with bowel wall thickness and vascularization score) and an ARFI elastography of the bowel wall were performed in 20 patients with UC and 13 healthy volunteers. At least 10 ARFI measurements were obtained within the terminal ileum and the ascending, transverse, descending, and sigmoid colon and correlated with results of high-frequency ultrasound. Results The UC group had mostly moderate disease activity. All patients had signs of inflammation upon B-mode ultrasound. Eight patients showed an ulcerative (ileo)pancolitis. Overall, ARFI elastography values and wall thickness were higher in the UC group than in the group of healthy volunteers ( P = 0.021 and P < 0.001, respectively). ARFI velocities of the separate segments were significantly higher in the transverse ( P = 0.045) and sigmoid colon ( P = 0.032) in case of UC. Conclusion ARFI elastography of the bowel wall of the colonic frame and the terminal ileum is feasible but shows high standard deviation. ARFI shear wave velocities appear to be slightly higher in patients with UC than in healthy volunteers, particularly in the sigmoid and transverse colon. Further studies are needed.

scholarly journals Does High Frequency Transcutaneous Electrical Nerve Stimulation (TENS) Affect EEG Gamma Band Activity?

2018 ◽  
Vol 8 (3Sep) ◽  
Author(s):  
M Ebrahimian ◽  
M Razeghi ◽  
A Zamani ◽  
Z Bagheri ◽  
K Rastegar ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Nerve Stimulation ◽  
High Frequency ◽  
Transcutaneous Electrical Nerve Stimulation ◽  
Gamma Band ◽  
Total Power ◽  
Electrical Nerve Stimulation ◽  
Tonic Pain ◽  
Gamma Band Activity ◽  
Band Activity

Background: Transcutaneous electrical nerve stimulation (TENS) is a noninvasive, inexpensive and safe analgesic technique used for relieving acute and chronic pain. However, despite all these advantages, there has been very little research into the therapeutic effects of TENS on brain activity. To the best of our knowledge, there is no evidence on the effect of high frequency TENS on the gamma band activity.  Objective: Investigation of the effect of high frequency TENS on the electroencephalographic (EEG) gamma band activity after inducing ischemic pain in healthy volunteers is considered.Methods: The modified version of Submaximal effort tourniquet test was carried out for inducing tonic pain in 15 right-handed healthy volunteers. The high frequency TENS (150µs in duration, frequency of 100 Hz) was applied for 20 minutes. Pain intensity was assessed using Visual Analog Scale (VAS) in two conditions (after-pain, after-TENS). EEG gamma band activity was recorded by a 19-channel EEG in three conditions (baseline, after-pain and after- TENS). The repeated measure ANOVA and paired-sample T- tests were used for data analysis.Results: EEG analysis showed an increase in gamma total power after inducing pain as compared to baseline and a decrease after the application of TENS (mean±SD: .043±.029 to .088±.042 to .038±.022 μV2 ).The analysis of VAS values demonstrated that the intensity of induced pain (mean±SD: 51.53±9.86) decreased after the application of TENS (mean±SD: 18.66±10.28). All these differences were statistically significant (p<.001).Conclusion: The results of this study revealed that the high frequency TENS can reduced the enhanced gamma band activity after the induction of tonic pain in healthy volunteers. This finding might help as a functional brain biomarker which could be useful for pain treatment, specifically for EEG-based neurofeedback approaches. 

scholarly journals Capabilities of computer analysis of breath sounds in patients with COVID-19

2021 ◽  
Vol 38 (3) ◽  
pp. 97-109
Author(s):  
E. G. Furman ◽  
A. O. Charushin ◽  
E. S. Eirikh ◽  
G. B. Furman ◽  
V. L. Sokolovsky ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Computer Analysis ◽  
High Frequency ◽  
Breath Sound ◽  
Respiratory Sound ◽  
Computer Diagnosis ◽  
Computer Methods ◽  
Breath Sounds ◽  
Healthy Persons ◽  
Diagnosis Of Diseases

Objective. To develop methods for a rapid distance computer diagnosis of COVID-19 based on the analysis of breath sounds. It is known that changes in breath sounds can be the indicators of respiratory organs diseases. Computer analysis of these sounds can indicate their typical changes caused by COVID-19, and can be used for a rapid preliminary diagnosis of this disease. Materials and methods. The method of fast Fourier transform (FFT) was used for computer analysis of breath sounds, recorded near the mouth of 14 COVID-19 patients (aged 1880 years) and 17 healthy volunteers (aged 548 years). The frequency of breath sound records ranged from 44 to 96 kHz. Unlike the conventional methods of computer analysis for diagnosis of diseases based on respiratory sound studying, we offer to test a high-frequency part of FFT (20006000 kHz). Results. While comparing the breath sound FFT in patients and healthy volunteers, we developed the methods for COVID-19 computer diagnosis and determined the numerical criteria in patients and healthy persons. These criteria do not depend on sex and age of the examined persons. Conclusions. The offered computer methods based on the analysis of breath sound FFT in patients and volunteers permit to diagnose COVID -19 with relatively high diagnostic parameters. These methods can be used in development of noninvasive means for preliminary self-express diagnosis of COVID-19.

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