Simple reaction time as a measure of global attention in Alzheimer's disease

1995 ◽  
Vol 1 (1) ◽  
pp. 56-61 ◽  
Author(s):  
Mary Sano ◽  
Wilma Rosen ◽  
Yaakov Stern ◽  
Jeffrey Rosen ◽  
Richard Mayeux

AbstractAlzheimer's disease (AD) is characterized by progressive decline in memory, language and other cognitive functions. Deficits in attentional processes have also been suggested. A simple reaction time (RT) task was used to assess global attention in AD. The length and consistency of a warning signal given prior to the response stimulus were manipulated to determine if patients with AD and age-matched controls benefit from predictability in RT tasks. Overall reaction time was slower in the AD group than in the and control group. Both groups demonstrated significant improvement in RT with long warning signals compared to short warning signals, but only the control group benefited from the consistency of the warning. (JINS, 1995, I, 56–61.)

2021 ◽  
Vol 11 (5) ◽  
pp. 669
Author(s):  
Paweł Krukow ◽  
Małgorzata Plechawska-Wójcik ◽  
Arkadiusz Podkowiński

Aggrandized fluctuations in the series of reaction times (RTs) are a very sensitive marker of neurocognitive disorders present in neuropsychiatric populations, pathological ageing and in patients with acquired brain injury. Even though it was documented that processing inconsistency founds a background of higher-order cognitive functions disturbances, there is a vast heterogeneity regarding types of task used to compute RT-related variability, which impedes determining the relationship between elementary and more complex cognitive processes. Considering the above, our goal was to develop a relatively new assessment method based on a simple reaction time paradigm, conducive to eliciting a controlled range of intra-individual variability. It was hypothesized that performance variability might be induced by manipulation of response-stimulus interval’s length and regularity. In order to verify this hypothesis, a group of 107 healthy students was tested using a series of digitalized tasks and their results were analyzed using parametric and ex-Gaussian statistics of RTs distributional markers. In general, these analyses proved that intra-individual variability might be evoked by a given type of response-stimulus interval manipulation even when it is applied to the simple reaction time task. Collected outcomes were discussed with reference to neuroscientific concepts of attentional resources and functional neural networks.


2018 ◽  
Vol 71 (7-8) ◽  
pp. 222-226
Author(s):  
Aleksandra Jakovljevic ◽  
Vojkan Nestorovic ◽  
Mirjana Dejanovic ◽  
Zoran Bukumiric ◽  
Aleksandar Jakovljevic ◽  
...  

Introduction. Hemodialysis patients with chronic renal failure, suffer from affective dysfunction to a variable extent. The aim of our study was to evaluate the cognitive and affective status in patients before and after hemodialysis. Apart from this, the goal of the study was to examine and compare the cognitive status of patients on dialysis in relation to the control group, but also in relation to laboratory parameters. Material and Methods. This research was a prospective study including 30 hemodialysis patients with chronic renal failure treated at the Department of Nephrology of the Health Center in Kosovska Mitrovica. The cognitive status of the subjects was evalueted by determining the simple reaction time to auditory and visual stimuli before and after hemodialysis sessions and using the Mini Mental Status Examination, while the affective status was evalueted by using the Beck Depression Inventory. Results. The analysis of the obtained results showed a statistically significantly lower auditory and visual simple reaction times (p = 0.014) after dialysis (p = 0.023). The results have confirmed a statistically significantly decreased simple reaction time to visual stimuli (p = 0.001), while a statistical significance (p = 0.137) was not obtained for the auditory stimuli when compared to the control group. The Mini Mental Status Examination and the Beck Depression Inventory did not indicate a significant cognitive status damage or presence of depression. Conclusion. The importance of hemodialysis in the improvement of cognitive function is clearly evident, even though the general state of cognitive status in patients on hemodialysis is lower compared to the healthy population. Evaluation of the cognitive and affective status using simple reaction time, Folstein?s Mini Mental State Examination and the Beck Depression Inventory, should be used on daily basis in hemodialysis patients.


2021 ◽  
Vol 13 (1) ◽  
pp. 231-236
Author(s):  
Monika Johne

Abstract Study aim: The symmetrisation of movements can be a way to develop individual coordinative skills, and to prevent the occur-rence of injuries. For this reason, in this study an attempt was made to evaluate and compare simple reaction time and movement time for épée fencers of different sports classes, and to determine the impact that three years of symmetrisation training and unilateral training have on the speed of reaction components and on dynamical asymmetry. Material and methods: The study was conducted on 60 women épée fencers of different sports classes, and it was repeated in two groups after three years of unilateral and symmetrisation training. Simple reaction time and movement time for the dominant and the non-dominant hand were analysed using Vienna Test System. Results: Women épée fencers of high sports class were characterised by a significantly faster reaction time than their less experienced colleagues. In tests conducted after three years of symmetrisation training, athletes from the experimental group achieved also much better results in reaction time (RT) than those from the control group training with the unilateral method. Conclusions: Long-time unilateral training of master class women épée fencers led to dynamical asymmetry, which in the future could cause injuries and have a negative impact on the development of selected motor skills. Symmetrical training conducted in the experimental group had a positive impact on reaction time indicators as well as on movement time indicators, and it prevented the occurrence of dynamical asymmetry in the tested competitors. Thus, it can be inferred that symmetrical exercises will have a positive impact on training effectiveness and on versatility of athletes.


1979 ◽  
Vol 49 (3) ◽  
pp. 831-835 ◽  
Author(s):  
Michel Sabourin ◽  
Serge Rioux

The goal of this study was to compare the effects of general relaxation (passive group) and neuromuscular tension control (active group), both using EMG biofeedback techniques, on the performance of memorization, simple reaction time, and rotary pursuit. 18 subjects were given five consecutive daily sessions of training or were placed under control conditions, after which their performance on these various tasks was evaluated. Results indicate that control of neuromuscular tension seemed to facilitate performance on all tasks over that of the control group. Except for simple reaction time, there was no difference between the “active” and “passive” groups. The results are interpreted in terms of factors in selection of subjects and experimental conditions.


2010 ◽  
Vol 26 (4) ◽  
pp. 229-238 ◽  
Author(s):  
Sahar Ali Farahat ◽  
Nirmeen Adel Kishk

The current work aimed at investigating the cognitive functions impairment among workers of sewer networks due to exposure to hydrogen sulfide (H2S) and the relation of this impairment, if any, to the level of H2S exposure biomarker ‘urinary thiosulfate.’ Besides, the validity of using Mini Mental State Examination (MMSE) as screening test for cognitive impairment among the exposed workers was tested. The work was conducted among 33 sewage network maintenance male workers and a matched unexposed control group (n = 30). The participants were subjected to clinical neurological history, estimation of urinary thiosulfate, and assessment of cognitive dysfunction by using neurophysiological (simple reaction time, P300 test) and neuropsychological tests (Wechsler Memory Scale) and frontal executive functions tests. Clinical neurological history revealed significantly higher neurological symptoms (headache, memory defects, lack of concentration) among exposed workers compared to their controls (p < 0.05). Exposed workers had significantly prolonged simple reaction time and delayed P300 latency and showed poor performance of most of neuropsychological tests. Marked elevation of urinary thiosulfate was observed among the exposed workers (p < 0.001) but this elevation was not correlated with the duration of exposure or any of the other measured parameters. Exposed workers had significantly lower mean value of MMSE scoring than that of the controls (p < 0.001). In conclusion, exposure to H 2S among sewer network workers is associated with cognitive impairment, which can be screened by applying MMSE as a simple rapid test for H 2S occupationally exposed workers.


1981 ◽  
Vol 52 (3) ◽  
pp. 1007-1010 ◽  
Author(s):  
Christine F. Summerford

A comparison was made to determine the effect of epilepsy on simple reaction time among 57 school-aged subjects. The subjects were classified intellectually as average, educable mentally retarded, or trainable mentally retarded, and neurologically as epileptic or nonepileptic. Following an explanation of the testing apparatus, 24 trials per day for five consecutive afternoons were given. The microswitch was depressed after a warning light and a foreperiod activated an audio response stimulus. A significant difference in RT was not found between subjects with epilepsy and those without epilepsy within each intellectual classification.


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