scholarly journals Evaluation of the cognitive and affective status in hemodialysis patients with chronic renal failure

2018 ◽  
Vol 71 (7-8) ◽  
pp. 222-226
Author(s):  
Aleksandra Jakovljevic ◽  
Vojkan Nestorovic ◽  
Mirjana Dejanovic ◽  
Zoran Bukumiric ◽  
Aleksandar Jakovljevic ◽  
...  

Introduction. Hemodialysis patients with chronic renal failure, suffer from affective dysfunction to a variable extent. The aim of our study was to evaluate the cognitive and affective status in patients before and after hemodialysis. Apart from this, the goal of the study was to examine and compare the cognitive status of patients on dialysis in relation to the control group, but also in relation to laboratory parameters. Material and Methods. This research was a prospective study including 30 hemodialysis patients with chronic renal failure treated at the Department of Nephrology of the Health Center in Kosovska Mitrovica. The cognitive status of the subjects was evalueted by determining the simple reaction time to auditory and visual stimuli before and after hemodialysis sessions and using the Mini Mental Status Examination, while the affective status was evalueted by using the Beck Depression Inventory. Results. The analysis of the obtained results showed a statistically significantly lower auditory and visual simple reaction times (p = 0.014) after dialysis (p = 0.023). The results have confirmed a statistically significantly decreased simple reaction time to visual stimuli (p = 0.001), while a statistical significance (p = 0.137) was not obtained for the auditory stimuli when compared to the control group. The Mini Mental Status Examination and the Beck Depression Inventory did not indicate a significant cognitive status damage or presence of depression. Conclusion. The importance of hemodialysis in the improvement of cognitive function is clearly evident, even though the general state of cognitive status in patients on hemodialysis is lower compared to the healthy population. Evaluation of the cognitive and affective status using simple reaction time, Folstein?s Mini Mental State Examination and the Beck Depression Inventory, should be used on daily basis in hemodialysis patients.

Author(s):  
Maheshkumar Kuppusamy ◽  
Dilara Kamaldeen ◽  
Ravishankar Pitani ◽  
Julius Amaldas ◽  
Padmavathi Ramasamy ◽  
...  

AbstractObjectivesThe improvement in the/reaction time is important, as it is an indicator of cognitive function. Therefore, there is a need, especially for adolescents in the form of techniques or courses that can improve the reaction time. Yoga was found to cause a better improvement in the health of the individuals. The present study intended to show the effects of Bhramari pranayama (Bhr.P) on reaction time in the healthy adolescents.MethodsOf the 730 potential subjects screened, 520 apparently healthy adolescents randomly assigned to either the Bhr.P group (n-260) or control group (n-260). Bhr.P group practiced the bhramari pranayama for 3 days in a week for 6 months. The Auditory Reaction Time (ART) and the Visual Reaction Time (VRT) were assessed before and after Bhr.P pranayama practice.ResultsBhr.P group shows significant shortening of response time in both VRT (from 267.13 ± 52.65 to 249.87 ± 39.41 ms) and ART (from 237.42 ± 48.12 to 227.91 ± 34.60 ms) after 6 months of Bhr.P practice. In control group subjects, no such significant changes were found (p > 0.05).ConclusionsShortening of RT implies an improvement in the information processing and reflexes. This beneficial effect of Bhr.P on reaction time can be used for improving cognitive function in the adolescents for their academic performances.


2021 ◽  
Author(s):  
Rehab H. Werida ◽  
Sohaila Abou-Madawy ◽  
Mohamed Abdelsalam ◽  
Maged Helmy

Abstract Chronic Renal failure patients on dialysis are at a high risk of death due to vascular calcification (VC). This study aimed at investigating the effect of omega3- fatty acids on the vascular calcification biomarkers fetuin-A and Osteoprotegerin (OPG) in patients with chronic renal failure (CRF) who are undergoing hemodialysis. This prospective, open-label, controlled, parallel study included 60 hemodialysis patients who were randomized to receive either omega-3 fatty acids capsule along with their standard care of treatment (omega-3 group) or their standard care of treatment only (control group). Serum levels of fetuin-A, OPG, calcium, phosphorus, hemoglobin, parathyroid hormone (PTH), blood urea nitrogen (BUN), albumin (ALB), serum creatinine (SCr), and serum triglycerides (TG) were measured at baseline and after six months of intervention and follow-up of both groups. Significantly increased levels of fetuin-A and OPG (p<0.001) were observed in the omega-3 group six months after the intervention compared with the control group. Levels of calcium, phosphorous, hemoglobin, parathyroid hormone, BUN, albumin, SCr, and TG were not significantly changed in the omega-3 group or the control group after six months of intervention. Our study concluded that omega-3 may have a clinically beneficial effect in decreasing cardiovascular events by increasing the levels of the protective vascular calcification inhibitors fetuin-A and osteoprotegerin in chronic renal failure patients who are undergoing hemodialysis.


2018 ◽  
Vol 2 (1) ◽  
pp. 42-50
Author(s):  
Errick Endra Cita ◽  
Dian Miftahul Mizan

Background: The number of new chronic renal failure patients with hemodialysis therapy continues to increase from year to year in Indonesia. When people learn they need to begin dialysis, they typically experience a flurry of emotions. The stress is caused by chronic illness accounts for a wide range of feelings and moods. This includes general irritability, anger and frustration over the problems caused by the illness, and feelings of being hopeless and helpless when faced with a life-threatening disease. Mind-body-spirit therapy (Concepts of Islam) focuses on the ability to manage the mindset and psychic that will affect the physical, attitudes and behavior of individuals in addressing their lives. Purpose : Giving mind-body-spirit therapy to hemodialysis patients to improve quality of life, given for 4 weeks with the frequency twice a week. Methods : Pre-experimental study with one group pre-test post-test. The sample of 23 patients with hemodialysis therapy taken by purposive sampling. The FACES test is a visual analog scale representation of mood was used in this study. Early screening on mood was taken in 23 patients (13 men and 10 women, mean age 51.5 years). Mind-body-spirit therapy (Islamic concept) consisted of Tausiyah (cognitive reconstruction), prayer, dhikr and drinking zam-zam water. The mood score was evaluated at week 4 after 4 weeks of treatments. Wilcoxon test results, obtained a significance value of 0,000 (p <0,05). This suggests "there are significant differences in mood conditions before and after the Mind Body Spirit therapy intervention (Islamic Concept). Result : After the treatments, there is an increase in the mood score of hemodialysis patients. Conclusion : A mind-body-spirit therapy of 4 weeks is effective for improving the mood of patients with chronic renal failure with hemodialysis therapy


1987 ◽  
Author(s):  
P Toulon ◽  
C Jacquot ◽  
M O Frydman ◽  
D Vignon ◽  
M Aiach

Anti thrombin III (AT III) and heparin cofactor II (HC II) were measured in 77 blood donors, 82 patients with chronic renal failure (CRF) undergoing regular hemodialysis and 36 undialyzed patients with CRF. AT III was measured as heparin cofactor and HC II as dermatan sulfate cofactor using amidolytic assays.The results (mean ± SD expressed in percentage of the in pooled normal plasma) are summurized in the table.Subnormal AT III levels were found in both dialyzed and undialyzed patients with CRF, while HC II was significantly (p < 0.001) reduced in dialyzed patients (12 of them were found to have HC II levels below to lowest value founded in our control group: 68 %).In order to explain this decrease of HC II level in dialyzed patients with CRF, we compared both AT III and HC II activities before and after a dialysis session in 24 patients (12 with a low and 12 with normal before dialysis HC II activity). AT III and HC II increased significantly (p < 0.01) in all patients after dialysis. When related to total plasma proteins in order to suppress the influence of hemoconcentration induced by dialysis, AT III decreased significantly (p < 0.01) in the 24 patients while HC II increased significantly (p < 0.01) only in patients with low before dialysis HC II levels (the increase in HC II activity was found significantly in the pooled 24 patients).


2019 ◽  
Vol 7 (1) ◽  
pp. 66-81
Author(s):  
Meylani Dewi Wowor ◽  
Ni Luh Widani ◽  
Emiliana Tjitra

Background: Chronic kidney failure (chronic renal failure) is a chronic disease that causes disruption of kidney function, so it requires kidney replacement therapy with long-term hemodialysis that must comply with fluid diets and can cause anxiety. Aims: Research to assess the effect of nursing psychoeducation on reducing anxiety levels and adherence to fluid diets in chronic renal failure patients with hemodialysis. Methods: The study was conducted in April-July 2018 in three private hospitals in Tomohon and Manado. This research is a quantitative study with a quasi-experimental pre-post test design with a control group of 112 respondents (82 in the intervention group and 30 in the control). Psychoeducation interventions are given according to the education module for 4 weeks, 2 times a week for a total of 8 meetings. Anxiety was assessed using the Beck Anxiety Inventory (BAI) questionnaire and adherence was assessed by the End Stage Renal Disease-Adherence Questionnaire (ESRD-AQ) before and after the study and weight observations at each visit. Results: Wilcoxon test results showed significant differences in anxiety levels (p <0.005) and fluid diet compliance (p <0.005) before and after the intervention. Mann Whitney test results showed no significant difference in decreasing anxiety level (p = 0.456) and increasing levels of fluid diet compliance (p = 0.495) between the intervention and control groups. The results of the ordinal logistic regression test, psychoeducation reduced anxiety levels by an OR of 6.5 times compared to the control group. The results of the binary logistic regression test, psychoeducation increased the level of adherence to the liquid diet with an OR value of 2.4 times compared to the control group. Conclusion: Psychoeducation can help reduce the level of anxiety and adherence to the fluid diet of patients with chronic renal failure with hemodialysis.


2019 ◽  
Vol 25 (3) ◽  
pp. 230-254
Author(s):  
Farid Reza Ejlali ◽  
◽  
Mahmood Reza Khazaei ◽  
Zahra Mostafavian ◽  
Jalil Moshari ◽  
...  

Aims The aim of this study was to evaluate the effect of discontinuation of losartan in response to synthetic erythropoietin therapy on hemoglobin level in patients on maintenance hemodialysis. Methods & Materials This study was a pre-and post-interventional clinical trial. The population of the study was hemodialysis patients with chronic renal failure. In the beginning of the study, and three months after removal of losartan, the patients’ hemoglobin changes were compared. Findings Hemoglobin was significantly increased at the end of the study in all patients (from 10.90±1.66 at the beginning of the study to 11.37±1.42g/dl at the end of 3 months, P=0.046). No significant changes were seen in the hemoglobin level before and after intervention between patients according age, sex, and duration of the disease. Conclusion There was a significant increase in hemoglobin level at the end of study after losartan discontinuation. But this increase did not have a significant relationship with patient’s age, sex as well as the duration of the disease.


1995 ◽  
Vol 1 (1) ◽  
pp. 56-61 ◽  
Author(s):  
Mary Sano ◽  
Wilma Rosen ◽  
Yaakov Stern ◽  
Jeffrey Rosen ◽  
Richard Mayeux

AbstractAlzheimer's disease (AD) is characterized by progressive decline in memory, language and other cognitive functions. Deficits in attentional processes have also been suggested. A simple reaction time (RT) task was used to assess global attention in AD. The length and consistency of a warning signal given prior to the response stimulus were manipulated to determine if patients with AD and age-matched controls benefit from predictability in RT tasks. Overall reaction time was slower in the AD group than in the and control group. Both groups demonstrated significant improvement in RT with long warning signals compared to short warning signals, but only the control group benefited from the consistency of the warning. (JINS, 1995, I, 56–61.)


Author(s):  
Frederico F. Gil ◽  
Maxlene J. Barros ◽  
Nazaré A. Macedo ◽  
Carmelino G. E. Júnior ◽  
Roseli Redoan ◽  
...  

Intestinal parasites are an important cause of morbidity and mortality. Immunocompromised individuals may develop more severe forms of these infections. Taking into account the immunity impairment in patients suffering from chronic renal failure (CRF), we will determine the prevalence and associated symptoms of intestinal parasites in these patients. Controls without CRF were used for comparison. Stool samples were collected and processed for microscopic identification of parasites using the Formalin-ether concentration method. For Cryptosporidium diagnosis, the ELISA technique was used. One hundred and ten fecal samples from hemodialysis patients were analyzed, as well as 86 from a community group used as control group. A result of 51.6% of intestinal parasites was observed in hemodialysis patients and 61.6% in the control group. Cryptosporidium and Blastocystis were the most common infections in patients with CRF (26.4% and 24.5%, respectively). Blastocystis was the most common infection in the control group (41.9%), however no individual was found positive for Cryptosporidium. Among the CRF patients, 73.6% were symptomatic, 54.3% of these tested positive for at least one parasite, in contrast to 44.8% in asymptomatic patients (p = 0.38). The most common symptoms in this group were flatulence (36.4%), asthenia (30.0%) and weight loss (30.0%). In the control group, 91.9% were symptomatic, 60.8% of these tested positive for at least one parasite, in contrast to 71.4% in asymptomatic patients (p = 0.703). A significant difference between the two groups was observed with regard to symptoms, with bloating, postprandial fullness, and abdominal pain being more frequent in the control group than in the hemodialysis group (all p < 0.05). Comparing symptomatic with asymptomatic, there was no association in either group between symptoms or the prevalence of parasitic infection, nor with the type of parasite or with multiple parasitic infections. Patients with chronic renal failure are frequent targets for renal transplantation, which as well as the inherent immunological impairment of the disease itself, results in immunosuppression by medication. For this reason, carriers of intestinal parasites with pathogenic potential can develop serious clinical complications influencing the success of transplantation. This fact, coupled with the high prevalence of intestinal parasites and the dissociation between symptoms and infection in CRF patients, suggests that the stool test should be incorporated in routine propedeutics. Furthermore, preventive measures for the acquisition of parasites through the fecal-oral contamination route should be introduced.


2021 ◽  
Vol 13 (1) ◽  
pp. 231-236
Author(s):  
Monika Johne

Abstract Study aim: The symmetrisation of movements can be a way to develop individual coordinative skills, and to prevent the occur-rence of injuries. For this reason, in this study an attempt was made to evaluate and compare simple reaction time and movement time for épée fencers of different sports classes, and to determine the impact that three years of symmetrisation training and unilateral training have on the speed of reaction components and on dynamical asymmetry. Material and methods: The study was conducted on 60 women épée fencers of different sports classes, and it was repeated in two groups after three years of unilateral and symmetrisation training. Simple reaction time and movement time for the dominant and the non-dominant hand were analysed using Vienna Test System. Results: Women épée fencers of high sports class were characterised by a significantly faster reaction time than their less experienced colleagues. In tests conducted after three years of symmetrisation training, athletes from the experimental group achieved also much better results in reaction time (RT) than those from the control group training with the unilateral method. Conclusions: Long-time unilateral training of master class women épée fencers led to dynamical asymmetry, which in the future could cause injuries and have a negative impact on the development of selected motor skills. Symmetrical training conducted in the experimental group had a positive impact on reaction time indicators as well as on movement time indicators, and it prevented the occurrence of dynamical asymmetry in the tested competitors. Thus, it can be inferred that symmetrical exercises will have a positive impact on training effectiveness and on versatility of athletes.


2019 ◽  
Vol 6 (1) ◽  
pp. 184-194
Author(s):  
Mehri Mirhaj Muhammadsalih ◽  
Rezhna Adil Rashid ◽  
Rowkhosh Ishaq Mekha

The present study, included 71 patients (41males and 30 females), suffering from chronic renal failure, who were attending Kidney Dialysis Center of Hawler Teaching Hospital in Erbil government, and 50 healthy individuals included as a control group. The sera were separated from patients and controls blood samples subjected to hematological studies. The aim of this study was to estimate changes in various hematological parameters in chronic renal failure patients before and after hemodialysis.      The study results showed that most of the hematological parameters were changed by hemodialysis in chronic kidney disease. Erythrocytes, hemoglobin, hematocrite were found to increase post-HD. The mean corpuscular volume, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration showed mild increase after hemodialysis. Leukocyte and platelet counts also showed mild increase after hemodialysis. It can be concluded that complete hematological parameters were found to increase after hemodialysis. Therefore, it is recommended that patients on hemodialysis should be investigated before and after hemodialysis to control the risk of anemia, bleeding or thrombosis.


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