Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-d-aspartic acid receptor up-regulation

Acid Receptor ◽

Microbiome Profiling Reveals Gut Dysbiosis in the Metabotropic Glutamate Receptor 5 Knockout Mouse Model of Schizophrenia

Frontiers in Cell and Developmental Biology ◽

10.3389/fcell.2020.582320 ◽

2020 ◽

Vol 8 ◽

Author(s):

Carolina Gubert ◽

Geraldine Kong ◽

Volkan Uzungil ◽

Ariel M. Zeleznikow-Johnston ◽

Emma L. Burrows ◽

...

Keyword(s):

Mouse Model ◽

Glutamate Receptor ◽

Knockout Mouse ◽

Knockout Mouse Model ◽

Metabotropic Glutamate ◽

Gut Dysbiosis ◽

Microbiome Profiling

Decrease in N-Methyl-d-aspartic Acid Receptor-NR2B Subunit Levels by Intrathecal Short-Hairpin RNA Blocks Group I Metabotropic Glutamate Receptor-Mediated Hyperalgesia

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.107.120071 ◽

2007 ◽

Vol 322 (1) ◽

pp. 186-194 ◽

Cited By ~ 20

Author(s):

Bichoy H. Gabra ◽

Fay K. Kessler ◽

Joseph K. Ritter ◽

William L. Dewey ◽

Forrest L. Smith

Keyword(s):

Aspartic Acid ◽

Glutamate Receptor ◽

Short Hairpin Rna ◽

Nr2b Subunit ◽

Hairpin Rna ◽

Acid Receptor ◽

Metabotropic Glutamate ◽

Group I ◽

Short Hairpin

The Effects of MPEP, a Selective Metabotropic Glutamate Receptor 5 Antagonist, on Conditioned Taste Aversion in Rats

PsycEXTRA Dataset ◽

10.1037/e413812005-369 ◽

2002 ◽

Author(s):

Todd R. Schachtman ◽

Carla Bills ◽

Rodica Ghinescu ◽

Kevin Murch ◽

Agnes Simonyi

Keyword(s):

Taste Aversion ◽

Glutamate Receptor ◽

Conditioned Taste Aversion ◽

Faculty Opinions recommendation of Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718499023.793498248 ◽

2014 ◽

Author(s):

Roland Seifert

Keyword(s):

Glutamate Receptor ◽

Transmembrane Domain ◽

Metabotropic Glutamate ◽

Class C

Faculty Opinions recommendation of Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu5) X-ray Structures.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732704940.793543297 ◽

2018 ◽

Author(s):

Dario Doller

Keyword(s):

G Protein ◽

Glutamate Receptor ◽

Allosteric Modulators ◽

G Protein Coupled Receptor ◽

X Ray ◽

Metabotropic Glutamate ◽

G Protein Coupled

Downregulation of metabotropic glutamate receptor 5 alleviates central sensitization by activating autophagy via inhibiting mTOR pathway in a rat model of chronic migraine

Neuroscience Letters ◽

10.1016/j.neulet.2020.135552 ◽

2021 ◽

Vol 743 ◽

pp. 135552

Author(s):

Yingying Niu ◽

Xiaoxu Zeng ◽

Guangcheng Qin ◽

Dunke Zhang ◽

Jiying Zhou ◽

...

Keyword(s):

Chronic Migraine ◽

Glutamate Receptor ◽

Rat Model ◽

Central Sensitization ◽

Mtor Pathway ◽

Allosteric enhancement of metabotropic glutamate receptor 5 function promotes spatial memory

Neuroscience ◽

10.1016/j.neuroscience.2006.06.043 ◽

2006 ◽

Vol 142 (3) ◽

pp. 691-702 ◽

Cited By ~ 67

Author(s):

D. Balschun ◽

W. Zuschratter ◽

W. Wetzel

Keyword(s):

Spatial Memory ◽

Glutamate Receptor ◽

Opposite regulation of metabotropic glutamate receptor 3 and metabotropic glutamate receptor 5 by inflammatory stimuli in cultured microglia and astrocytes

Neuroscience ◽

10.1016/j.neuroscience.2011.12.044 ◽

2012 ◽

Vol 205 ◽

pp. 29-38 ◽

Cited By ~ 26

Author(s):

J.V. Berger ◽

A.O. Dumont ◽

M.C. Focant ◽

M. Vergouts ◽

A. Sternotte ◽

...

Keyword(s):

Glutamate Receptor ◽

Metabotropic Glutamate ◽

Metabotropic Glutamate Receptor 3 ◽

Inflammatory Stimuli

Chronic corticosterone administration down-regulates metabotropic glutamate receptor 5 protein expression in the rat hippocampus

Neuroscience ◽

10.1016/j.neuroscience.2010.06.023 ◽

2010 ◽

Vol 169 (4) ◽

pp. 1567-1574 ◽

Cited By ~ 25

Author(s):

A.H. Iyo ◽

A.M. Feyissa ◽

A. Chandran ◽

M.C. Austin ◽

S. Regunathan ◽

...

Keyword(s):

Protein Expression ◽

Glutamate Receptor ◽

Rat Hippocampus ◽

Metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine (MPEP) microinfusions into the nucleus accumbens shell or ventral tegmental area attenuate the reinforcing effects of nicotine in rats

Neuropharmacology ◽

10.1016/j.neuropharm.2011.08.028 ◽

2011 ◽

Vol 61 (8) ◽

pp. 1399-1405 ◽

Cited By ~ 28

Author(s):

Manoranjan S. D’Souza ◽

Athina Markou

Keyword(s):

Nucleus Accumbens ◽

Ventral Tegmental Area ◽

Glutamate Receptor ◽

Nucleus Accumbens Shell ◽

Metabotropic Glutamate ◽

Reinforcing Effects ◽

Ventral Tegmental