Application of Atmospheric Pressure Ionization Time-of-Flight Mass Spectrometry Coupled with Liquid Chromatography for the Characterization of in Vitro Drug Metabolites

Analytical Chemistry ◽

10.1021/ac000089r ◽

2000 ◽

Vol 72 (14) ◽

pp. 3342-3348 ◽

Author(s):

Hongwei Zhang ◽

Jack Henion ◽

Yi Yang ◽

Neil Spooner

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Atmospheric Pressure ◽

Time Of Flight ◽

Atmospheric Pressure Ionization ◽

Ionization Time ◽

Drug Metabolites ◽

Flight Mass Spectrometry

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Characterization of in Vitro Metabolism of Loganin by Human Intestinal Microflora Using Ultra-High Performance Liquid Chromatography–Quadrupole Time-of-Flight Mass Spectrometry

Analytical Letters ◽

10.1080/00032719.2013.876543 ◽

2014 ◽

Vol 47 (9) ◽

pp. 1500-1512 ◽

Author(s):

Min Zhao ◽

Jun Xu ◽

Dawei Qian ◽

Jianming Guo ◽

Shu Jiang ◽

...

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

High Performance ◽

Intestinal Microflora ◽

Time Of Flight ◽

In Vitro Metabolism ◽

Flight Mass Spectrometry

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Characterization of in vitro metabolites of trimethoprim and diaveridine in pig liver microsomes by liquid chromatography combined with hybrid ion trap/time-of-flight mass spectrometry

Biomedical Chromatography ◽

10.1002/bmc.1754 ◽

2011 ◽

Vol 26 (9) ◽

pp. 1101-1108 ◽

Author(s):

Zhao-Ying Liu ◽

Yong Wu ◽

Zhi-Liang Sun ◽

Leren Wan

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Ion Trap ◽

Liver Microsomes ◽

Time Of Flight ◽

Pig Liver ◽

Flight Mass Spectrometry

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Atmospheric pressure ionization time-of-flight mass spectrometry with a supersonic ion beam

Analytical Chemistry ◽

10.1021/ac00024a018 ◽

1991 ◽

Vol 63 (24) ◽

pp. 2897-2900 ◽

Author(s):

Chung Hang. Sin ◽

Edgar D. Lee ◽

Milton L. Lee

Keyword(s):

Mass Spectrometry ◽

Atmospheric Pressure ◽

Ion Beam ◽

Time Of Flight ◽

Atmospheric Pressure Ionization ◽

Ionization Time ◽

Flight Mass Spectrometry

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Liquid chromatography-quadrupole time-of-flight mass spectrometry for screening in vitro drug metabolites in humans: investigation on seven phenethylamine-based designer drugs

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2015.06.016 ◽

2015 ◽

Vol 114 ◽

pp. 355-375 ◽

Author(s):

Foon Yin Lai ◽

Claudio Erratico ◽

Juliet Kinyua ◽

Jochen F. Mueller ◽

Adrian Covaci ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Time Of Flight ◽

Designer Drugs ◽

Drug Metabolites ◽

Flight Mass Spectrometry ◽

Screening In Vitro

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Atmospheric pressure ionization time-of-flight mass spectrometry coupled with fast liquid chromatography for quantitation and accurate mass measurement of five pharmaceutical drugs in human plasma

Journal of Mass Spectrometry ◽

10.1002/(sici)1096-9888(200003)35:3<423::aid-jms953>3.0.co;2-7 ◽

2000 ◽

Vol 35 (3) ◽

pp. 423-431 ◽

Author(s):

Hongwei Zhang ◽

Katja Heinig ◽

Jack Henion

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Human Plasma ◽

Atmospheric Pressure ◽

Mass Measurement ◽

Pharmaceutical Drugs ◽

Atmospheric Pressure Ionization ◽

Ionization Time ◽

Flight Mass Spectrometry ◽

Fast Liquid Chromatography

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Characterization of Steroidal Saponins in Crude Extracts from Dioscorea Species using Liquid Chromatography/Electrospray Ionization Time-of-Flight Mass Spectrometry

Planta Medica ◽

10.1055/s-0032-1307643 ◽

2012 ◽

Vol 78 (05) ◽

Author(s):

B Avula ◽

YH Wang ◽

M Wang ◽

Z Ali ◽

IA Khan

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Electrospray Ionization ◽

Time Of Flight ◽

Steroidal Saponins ◽

Ionization Time ◽

Flight Mass Spectrometry ◽

Crude Extracts ◽

Dioscorea Species

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Characterization of in vitro metabolites of three tetrahydroprotoberberine alkaloids in rat liver S9 by high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.8199 ◽

2018 ◽

Vol 32 (17) ◽

pp. 1540-1548 ◽

Author(s):

Li Lin ◽

Xiu-Bin Liu ◽

Qiao-Yun Zhou ◽

Sha-Sha Liu ◽

Meng-Ting Zuo ◽

...

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Rat Liver ◽

High Performance ◽

Time Of Flight ◽

Flight Mass Spectrometry

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Global characterization of neutral saccharides in crude and processed Radix Rehmanniae by hydrophilic interaction liquid chromatography tandem electrospray ionization time-of-flight mass spectrometry

Food Chemistry ◽

10.1016/j.foodchem.2013.04.114 ◽

2013 ◽

Vol 141 (3) ◽

pp. 2833-2840 ◽

Author(s):

Zhirui Liu ◽

Ziyang Lou ◽

Xuan Ding ◽

Xiang Li ◽

Yunpeng Qi ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Electrospray Ionization ◽

Time Of Flight ◽

Hydrophilic Interaction Liquid Chromatography ◽

Hydrophilic Interaction ◽

Ionization Time ◽

Flight Mass Spectrometry

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Systematic characterization of the chemical constituents in vitro and prototypes in vivo of Dingkun Dan using ultra‐high‐performance liquid chromatography quadrupole time‐of‐flight mass spectrometry combined with the UNIFI™ software

Biomedical Chromatography ◽

10.1002/bmc.4914 ◽

2020 ◽

Vol 34 (10) ◽

Author(s):

Xiu‐xiu Dou ◽

Shan Lin ◽

Xin‐hui Tian ◽

Yu‐hao Zhang ◽

Xin Guo ◽

...

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

High Performance ◽

Chemical Constituents ◽

Time Of Flight ◽

Flight Mass Spectrometry

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Quantitative Characterization of Solid Epoxy Resins Using Comprehensive Two Dimensional Liquid Chromatography Coupled with Electrospray Ionization-Time of Flight Mass Spectrometry

Analytical Chemistry ◽

10.1021/ac9001047 ◽

2009 ◽

Vol 81 (11) ◽

pp. 4271-4279 ◽

Author(s):

Samir Julka ◽

Hernan Cortes ◽

Robert Harfmann ◽

Bruce Bell ◽

Andreas Schweizer-Theobaldt ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Electrospray Ionization ◽

Epoxy Resins ◽

Time Of Flight ◽

Two Dimensional ◽

Quantitative Characterization ◽

Ionization Time ◽

Flight Mass Spectrometry

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