Solid Phase Trapping Mechanisms Involved in the Supercritical Fluid Extraction of Digitalis Glycosides with Modified Carbon Dioxide

1995 ◽  
Vol 67 (13) ◽  
pp. 2030-2036 ◽  
Author(s):  
W. N. Moore ◽  
L. T. Taylor
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Solid Phase ◽  
Fluid Extraction ◽  
Digitalis Glycosides

Supercritical Fluid Extraction of Aflatoxin M1 from Beef Livert†

1997 ◽  
Vol 60 (6) ◽  
pp. 698-700 ◽  
Author(s):  
SCOTT L. TAYLOR ◽  
JERRY W. KING ◽  
JUDITH I. GREER ◽  
JOHN L. RICHARD
Keyword(s):  
Carbon Dioxide ◽  
Organic Solvent ◽  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
High Performance ◽  
Methylene Chloride ◽  
Solid Phase ◽  
Aflatoxin M1 ◽  
Organic Modifiers ◽  
Fluid Extraction

Supercritical fluid extraction (SFE) and a pressurized-fluid-extraction process were applied for the removal of aflatoxin M1 from beef liver samples. Various pressures, temperatures, quantity of supercritical carbon dioxide, and organic modifiers were investigated to optimize the extraction methods. Organic modifier was found to be essential for quantitative recovery of aflatoxin M1. Extracts were cleaned up by solid-phase extraction and were analyzed via high-performance liquid chromatography coupled with fluorescence detection of the trifluoroacetic acid derivative. Solvent-modified carbon dioxide SFE achieved recoveries comparable to an AOAC-approved method involving organic solvent extraction. SFE allowed the traditional amounts of sample and organic solvent to be reduced. Also, the supercritical-fluid extraction permitted the use of carbon dioxide modified with acetonitrile: methanol (2:1) to replace methylene chloride as the organic solvent for the extraction step.

Collection efficiency of various solid-phase traps for off-line supercritical fluid extraction

1991 ◽  
Vol 63 (20) ◽  
pp. 2225-2232 ◽  
Author(s):  
L. J. Mulcahey ◽  
J. L. Hedrick ◽  
L. T. Taylor
Keyword(s):  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Solid Phase ◽  
Collection Efficiency ◽  
Fluid Extraction

scholarly journals Supercritical Fluid Extraction of Pyrrolidine Alkaloid from Leaves of Piper amalago L.

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
V. S. Carrara ◽  
L. C. Filho ◽  
V. A. S. Garcia ◽  
V. S. Faiões ◽  
E. F. Cunha-Júnior ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Orthogonal Array ◽  
Design Matrix ◽  
Supercritical Carbon Dioxide Extraction ◽  
Orthogonal Array Design ◽  
Fluid Extraction ◽  
Array Design ◽  
Carbon Dioxide Extraction

Supercritical fluid extraction was used to extract the alkaloid N-[7-(3′,4′-methylenedioxyphenyl)-2(Z),4(Z)-heptadienoyl]pyrrolidine from leaves of Piper amalago L. A three-level orthogonal array design matrix, OAD OA9(34), was used for optimization of the parameters of supercritical extraction of the alkaloid, employing supercritical carbon dioxide: extraction time (20, 40, and 60 min), temperature (40, 50, and 60°C), pressure (150, 200, and 250 bar), and the use of cosolvents (ethanol, methanol, and propyleneglycol). All parameters had significant effect on the alkaloid yield. The alkaloid yield after 60 min of extraction without cosolvents at 9 different conditions (32) in terms of temperature (40, 50, and 60°C) and pressure (150, 200, and 250 bar) was also evaluated. The optimal yield (≈3.8 mg g−1) was obtained with supercritical CO2 + methanol (5% v : v) at 40°C and 200 bar for 60 min of extraction.

scholarly journals NILAI TAMBAH MINYAK AKAR WANGI DENGAN PEMEKATAN KADAR VETIVEROL MENGGUNAKAN EKSTRAKSI CO2 FLUIDA SUPERKRITIK

2014 ◽  
Vol 16 (2) ◽  
pp. 76-81 ◽  
Author(s):  
Anny Sulaswatty ◽  
Egi Agustian
Keyword(s):  
Carbon Dioxide ◽  
Refractive Index ◽  
Specific Gravity ◽  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Flow Rate ◽  
Optical Rotation ◽  
Process Conditions ◽  
Fluid Extraction ◽  
Great Opportunity

Potensi Indonesia akan minyak akar wangi yang berorientasi ekspor dalam industri kosmetik, parfum, sabun, keperluan terapi, antiseptik, massage oil, farmasi dan pestisida memberikan peluang yang besar untuk memenuhi kebutuhan dunia. Guna nilai tambah minyak akar wangi dengan meningkatkan kadar vetiverol sebagai komponen utama, diaplikasikan teknologi ekstraksi fluida karbondioksida superkritik yang merupakan perpaduan ekstraksi, fraksinasi dan deodorisasi dengan didukung keunggulan karbondioksida sebagai pelarut yang inert, ramah lingkungan, mudah dipisahkan, dan berdaya larut tinggi.  Minyak akar wangi Garut (Java vetiver oil) sebagai bahan baku, mempunyai karakteristik  kadar vetiverol  39.03 %; Bobot jenis 0.9977; indeks bias 1.5247;  putaran optik +38.1; kelarutan dalam alkohol 95%  yaitu 1:1 jernih; bilangan asam 28.1; bilangan ester 24.6; bilangan ester setelah asetilasi 115.5; serta tidak mengandung minyak lemak dan  minyak keruing. Pemilihan kondisi proses guna menghasilkan kandungan vetiverol optimal dilakukan dengan memvariasikan laju alir gas CO2, tekanan dan suhu sebagai parameter penting dalam keberhasilan proses ekstraksi minyak akar wangi dengan fluida CO2 superkritik. Pemilihan laju alir konstan dan lebih stabil  diperoleh pada 5.5 liter/menit, sedangkan untuk variasi tekanan ekstraktor (1500, 1750, 2000 psi) dan suhu ekstraktor (40-50oC);  tekanan dan suhu separator  500 psi dan 25oC serta waktu proses selama lima jam dengan pengambilan ekstrak setiap jam. Tekanan dan suhu proses yang optimal diperoleh pada 1750 psi dan suhu 40oC  dengan  rafinat minyak akar wangi berkadar vetiverol  51.82 %,  bilangan ester 7.2 dan bilangan ester setelah asetilasi  172.4. Tingginya tekanan dan rendahnya suhu berpengaruh terhadap perolehan ekstrak; penurunan rafinat; peningkatan nilai  bobot jenis ekstrak dan rafinat; indeks bias ekstrak dan rafinat; putaran optik ekstrak dan rafinat; peningkatan viskositas ekstrak dan rafinat; peningkatan bilangan ester ekstrak, bilangan ester setelah asetilasi ekstrak, serta kandungan vetiverol.Kata Kunci: Minyak Akar Wangi, Vetiverol, Ekstraksi Fluida Superkritik Potential Indonesian vetiver oil export oriented industry of cosmetics, perfumes, soaps, therapeutic purposes, antiseptic, massage oil, pharmaceutical and pesticide presents a great opportunity to meet the needs of the world. In order to add value vetiver oil by increasing the levels vetiverol as the main component, was applied to carbon dioxide supercritical fluid extraction technology which is a combination of extraction, fractionation and deodorization with excellence supported carbon dioxide as an inert solvent, eco-friendly, easily separated, and the high solubility. Garut vetiver oil (Java vetiver oil) as raw material, has the characteristics vetiverol levels 39.03%, specific gravity of 0.9977; refractive index of 1.5247; optical rotation +38.1; solubility in alcohol 95% is a clear 1:1; acid number 28.1; ester number 24.6; ester number after acetylation 115.5; as well as fats and oils contain no oil keruing. The selection process conditions in order to produce optimal vetiverol content performed by varying the flow rate of CO2 gas, pressure and temperature as an important parameter in the success of vetiver oil extraction with supercritical CO2 fluid. The selection of a constant flow rate and more stable obtained at 5.5 liters / min, whereas for pressure variation extractor (1500-2000 psi) and extractor temperature (40-50oC); separator pressure and temperature of 500 psi and 25 °C as well as the processing time for five hours by taking extracts every hour. Pressure and temperature optimum process obtained at 1750 psi and a temperature of 40oC with rafinat vetiverol vetiver oil yield of 51.82%, ester number 7.2, and ester number after acetylation 172.4. The high pressure and low temperature affect the acquisition of the extract; rafinat decline; increase in the value of specific gravity and rafinat extracts; refractive index and rafinat extract; optical rotation and rafinat extract; increase in the viscosity of the extract and rafinat; increase in numbers ester extract, ester number after acetylation extracts, as well as the content vetiverol. Key word: Vetiver Oil, Vetiverol, Supercritical Fluid Extraction.

Supercritical Fluid Extraction: Carbon Dioxide

2016 ◽  
pp. 1-3
Author(s):  
Hiroaki Takeda ◽  
Yoshihiro Izumi ◽  
Takeshi Bamba
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Fluid Extraction

Supercritical fluid extraction of bitumen using chemically modified carbon dioxide

2019 ◽  
Vol 154 ◽  
pp. 104599 ◽  
Author(s):  
Heidi L. Cossey ◽  
Selma E. Guigard ◽  
Eleisha Underwood ◽  
Warren H. Stiver ◽  
Jennifer McMillan ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Fluid Extraction ◽  
Chemically Modified

scholarly journals Supercritical Fluid Extraction of Halogenated Monoterpenes from the Red Alga Plocamium cartilagineum

2001 ◽  
Vol 84 (5) ◽  
pp. 1313-1331 ◽  
Author(s):  
Donqhui Gao ◽  
Roy Okuda ◽  
Viorica Lopez-Avila
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Biological Activities ◽  
Red Alga ◽  
Fluid Extraction ◽  
The Pacific ◽  
Halogenated Monoterpenes ◽  
Conventional Solvent Extraction ◽  
Plocamium Cartilagineum

Abstract Supercritical fluid extraction (SFE) of the marine red alga Plocamium cartilagineum, which is known to contain complex mixtures of halogenated monoterpenes, was investigated. P. cartilagineum samples were extracted by SFE with carbon dioxide and modified carbon dioxide containing up to 10% methanol at different pressure and temperature conditions to establish the optimum conditions for extraction. These conditions were then used in the extraction of halogenated monoterpenes from 2 different samples of P. cartilagineum: one from Davenport, CA, and the other from Casa Beach (San Diego, CA). Several halogenated monoterpenes isolated by conventional solvent extraction with methanol and purified by column chromatography were used as the reference compounds for the determination of the extraction efficiency in the SFE experients. Plocamium cartilagineum belongs to the red alga family—Plocamiaceae, and has been found to contain a large number of halogenated monoterpenes, whose structures typically contain 1–6 bromine and/or chlorine atoms. P. cartilagineum grows along the Pacific coast from Washington to Chile, the British Isles, Australia, and Spain. Interestingly, P. cartilagineum collected from different geographical areas in the world are all reported to produce halogenated monoterpenes, but of different structural types and halogen substitution patterns. Most of these halogenated monoterpenes have been found to exhibit varied biological activities, including antifungal, antimicrobial, and molluscicidal activity.

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