scholarly journals Ultrasound-Enhanced Attenuated Total Reflection Mid-infrared Spectroscopy In-Line Probe: Acquisition of Cell Spectra in a Bioreactor

2015 ◽  
Vol 87 (4) ◽  
pp. 2314-2320 ◽  
Author(s):  
Cosima Koch ◽  
Markus Brandstetter ◽  
Patrick Wechselberger ◽  
Bettina Lorantfy ◽  
Maria Reyes Plata ◽  
...  
2017 ◽  
Vol 89 (10) ◽  
pp. 5285-5293 ◽  
Author(s):  
Aazam Khoshmanesh ◽  
Dale Christensen ◽  
David Perez-Guaita ◽  
Inaki Iturbe-Ormaetxe ◽  
Scott L. O’Neill ◽  
...  

The Analyst ◽  
2018 ◽  
Vol 143 (13) ◽  
pp. 3156-3163 ◽  
Author(s):  
Maria Paraskevaidi ◽  
Camilo L. M. Morais ◽  
Kássio M. G. Lima ◽  
Katherine M. Ashton ◽  
Helen F. Stringfellow ◽  
...  

Attenuated total reflection FTIR (ATR-FTIR) spectroscopy has been combined with chemometrics to detect women with endometrial and ovarian carcinomas using non-invasively collected urine samples.


Sensors ◽  
2019 ◽  
Vol 19 (23) ◽  
pp. 5130 ◽  
Author(s):  
Ine L. Jernelv ◽  
Karina Strøm ◽  
Dag Roar Hjelme ◽  
Astrid Aksnes

The development of rapid and accurate biomedical laser spectroscopy systems in the mid-infrared has been enabled by the commercial availability of external-cavity quantum cascade lasers (EC-QCLs). EC-QCLs are a preferable alternative to benchtop instruments such as Fourier transform infrared spectrometers for sensor development as they are small and have high spectral power density. They also allow for the investigation of multiple analytes due to their broad tuneability and through the use of multivariate analysis. This article presents an in vitro investigation with two fiber-coupled measurement setups based on attenuated total reflection spectroscopy and direct transmission spectroscopy for sensing. A pulsed EC-QCL (1200–900 cm − 1 ) was used for measurements of glucose and albumin in aqueous solutions, with lactate and urea as interferents. This analyte composition was chosen as an example of a complex aqueous solution with relevance for biomedical sensors. Glucose concentrations were determined in both setup types with root-mean-square error of cross-validation (RMSECV) of less than 20 mg/dL using partial least-squares (PLS) regression. These results demonstrate accurate analyte measurements, and are promising for further development of fiber-coupled, miniaturised in vivo sensors based on mid-infrared spectroscopy.


Foods ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 477
Author(s):  
Eduarda Mendes ◽  
Noélia Duarte

Nowadays, food adulteration and authentication are topics of utmost importance for consumers, food producers, business operators and regulatory agencies. Therefore, there is an increasing search for rapid, robust and accurate analytical techniques to determine the authenticity and to detect adulteration and misrepresentation. Mid-infrared spectroscopy (MIR), often associated with chemometric techniques, offers a fast and accurate method to detect and predict food adulteration based on the fingerprint characteristics of the food matrix. In the first part of this review the basic concepts of infrared spectroscopy, sampling techniques, as well as an overview of chemometric tools are summarized. In the second part, recent applications of MIR spectroscopy to the analysis of foods such as coffee, dairy products, honey, olive oil and wine are discussed, covering a timespan from 2010 to mid-2020. The literature gathered in this article clearly reveals that the MIR spectroscopy associated with attenuated total reflection acquisition mode and different chemometric tools have been broadly applied to address quality, authenticity and adulteration issues. This technique has the advantages of being simple, fast and easy to use, non-destructive, environmentally friendly and, in the future, it can be applied in routine analyses and official food control.


Sign in / Sign up

Export Citation Format

Share Document