Powerful Steroid-Based Chiral Selector for High-Throughput Enantiomeric Separation of α-Amino Acids Utilizing Ion Mobility–Mass Spectrometry

2021 ◽  
Author(s):  
Yuling Li ◽  
Bowen Zhou ◽  
Keke Wang ◽  
Jing Zhang ◽  
Wenjian Sun ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Amino Acids ◽  
High Throughput ◽  
Ion Mobility ◽  
Enantiomeric Separation ◽  
Chiral Selector ◽  
Ion Mobility Mass Spectrometry

Enantiomeric differentiation of aromatic amino acids using traveling wave ion mobility-mass spectrometry

2014 ◽  
Vol 5 (8) ◽  
pp. 3234-3239 ◽  
Author(s):  
Virginie Domalain ◽  
Marie Hubert-Roux ◽  
Vincent Tognetti ◽  
Laurent Joubert ◽  
Catherine M. Lange ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Amino Acids ◽  
Ion Mobility ◽  
Traveling Wave ◽  
Aromatic Amino Acids ◽  
Ion Mobility Mass Spectrometry ◽  
Traveling Wave Ion Mobility

The present work describes the first differentiation of amino acids enantiomers using the coupling of traveling wave ion mobility and mass spectrometry.

Rapid and sensitive monitoring of biocatalytic reactions using ion mobility mass spectrometry

The Analyst ◽  
2016 ◽  
Vol 141 (8) ◽  
pp. 2351-2355 ◽  
Author(s):  
Cunyu Yan ◽  
Jason W. Schmidberger ◽  
Fabio Parmeggiani ◽  
Shaneela A. Hussain ◽  
Nicholas J. Turner ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Stable Isotope ◽  
High Throughput ◽  
Ion Mobility ◽  
Ion Mobility Mass Spectrometry ◽  
Direct Infusion ◽  
Stable Isotope Labelling ◽  
Isotope Labelling

The combination of stable isotope labelling with direct infusion ion mobility mass spectrometry enabled high-throughput and sensitive monitoring of biocatalytic reactions.

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