Electrochemiluminescence Resonance Energy Transfer System Based on Silver Metal–Organic Frameworks as a Double-Amplified Emitter for Sensitive Detection of miRNA-107

Author(s):  
Siyu Xiao ◽  
Xiaoyan Wang ◽  
Changping Yang ◽  
Yongjian Jiang ◽  
Shujun Zhen ◽  
...  
Nanomaterials ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 1925
Author(s):  
Changwon Seo ◽  
Miyeon Kim ◽  
Jubok Lee ◽  
Chang Yeon Lee ◽  
Jeongyong Kim

Metal–organic frameworks (MOFs) represent a class of solid-state hybrid compounds consisting of multitopic organic struts and metal-based nodes that are interconnected by coordination bonds, and they are ideal for light harvesting due to their highly ordered structure. These structures can be constructed with chromophore organic ligands structures for the purpose of efficient light harvesting. Here, we prepared porphyrin-based nano-scaled MOFs (nPCN-222) with BODIPY and I2BODIPY photosensitizers by incorporating BODIPY/I2BODIPY into nPCN-222 (nPCN-BDP/nPCN-I2BDP) and demonstrated resonance energy transfer from the donor (BODIPY/I2BODIPY) to the acceptor (nPCN-222) resulting in greatly enhanced fluorescence of nPCN-222, as visually manifested by time-resolved and space-resolved fluorescence imaging of the nano-scaled MOFs.


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