Mitochondria-Targeted Fluorescent Probe for Imaging Hydrogen Peroxide in Living Cells

2015 ◽  
Vol 88 (2) ◽  
pp. 1455-1461 ◽  
Author(s):  
Jian Xu ◽  
Yan Zhang ◽  
Hui Yu ◽  
Xudong Gao ◽  
Shijun Shao
Keyword(s):  
Hydrogen Peroxide ◽  
Fluorescent Probe ◽  
Living Cells

A lysosome targetable fluorescent probe for endogenous imaging of hydrogen peroxide in living cells

2017 ◽  
Vol 53 (26) ◽  
pp. 3701-3704 ◽  
Author(s):  
Shahi Imam Reja ◽  
Muskan Gupta ◽  
Neha Gupta ◽  
Vandana Bhalla ◽  
Puja Ohri ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Fluorescent Probe ◽  
Living Cells

A lysosome targetable naphthalimide based fluorescent probe has been designed and synthesized for selective imaging of H2O2 in different cells, tissues and in vivo models.

Rational design of a far-red fluorescent probe for endogenous biothiol imbalance induced by hydrogen peroxide in living cells and mice

2020 ◽  
Vol 103 ◽  
pp. 104173
Author(s):  
Zhengliang Lu ◽  
Xin Sun ◽  
Mengzhao Wang ◽  
Hongmei Wang ◽  
Chunhua Fan ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Fluorescent Probe ◽  
Rational Design ◽  
Living Cells

A mitochondria-targetable fluorescent probe with a large Stokes shift for detecting hydrogen peroxide in aqueous solution and living cells

2017 ◽  
Vol 41 (9) ◽  
pp. 3320-3325 ◽  
Author(s):  
Yong Liu ◽  
Jie Niu ◽  
Jing Nie ◽  
Fangfang Meng ◽  
Weiying Lin
Keyword(s):  
Aqueous Solution ◽  
Hydrogen Peroxide ◽  
Fluorescent Probe ◽  
Stokes Shift ◽  
Living Cells ◽  
Fluorescent Dye ◽  
Large Stokes Shift

In this work, we introduce a carbazole-based fluorophore as a novel fluorescent dye for developing a mitochondria-targetable fluorescent probe with a large Stokes shift and it was used for detection of H2O2in aqueous solution and living cells.

An extremely rapid-response fluorescent probe for hydrogen peroxide and its application in living cells

RSC Advances ◽  
2016 ◽  
Vol 6 (92) ◽  
pp. 89940-89943 ◽  
Author(s):  
Fuxu Zhan ◽  
Qian Yang ◽  
Qiufen Wang ◽  
Qilong Zhang ◽  
Zhiyuan Zhuang ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Fluorescent Probe ◽  
Living Cells ◽  
Rapid Response ◽  
Biological Processes

An extremely rapid-response fluorescent probe for H2O2was constructed for monitoring the H2O2levels in biological processes.

scholarly journals A Novel Fluorescent Probe for Hydrogen Peroxide and Its Application in Bio-Imaging

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3352
Author(s):  
Yingying Zuo ◽  
Yang Jiao ◽  
Chunming Ma ◽  
Chunying Duan
Keyword(s):  
Hydrogen Peroxide ◽  
Fluorescent Probe ◽  
Human Body ◽  
Fluorescence Enhancement ◽  
Fluorescent Sensor ◽  
Living Cells ◽  
Promising Tool ◽  
Bio Imaging ◽  
Good Biocompatibility ◽  
The Relationship

Hydrogen peroxide (H2O2) plays an important role in the human body and monitoring its level is meaningful due to the relationship between its level and diseases. A fluorescent sensor (CMB) based on coumarin was designed and its ability for detecting hydrogen peroxide by fluorescence signals was also studied. The CMB showed an approximate 25-fold fluorescence enhancement after adding H2O2 due to the interaction between the CMB and H2O2 and had the potential for detecting physiological H2O2. It also showed good biocompatibility and permeability, allowing it to penetrate cell membranes and zebrafish tissues, thus it can perform fluorescence imaging of H2O2 in living cells and zebrafish. This probe is a promising tool for monitoring the level of H2O2 in related physiological and pathological research.

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