scholarly journals A Novel Fluorescent Probe for Hydrogen Peroxide and Its Application in Bio-Imaging

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3352
Author(s):  
Yingying Zuo ◽  
Yang Jiao ◽  
Chunming Ma ◽  
Chunying Duan
Keyword(s):  
Hydrogen Peroxide ◽  
Fluorescent Probe ◽  
Human Body ◽  
Fluorescence Enhancement ◽  
Fluorescent Sensor ◽  
Living Cells ◽  
Promising Tool ◽  
Bio Imaging ◽  
Good Biocompatibility ◽  
The Relationship

Hydrogen peroxide (H2O2) plays an important role in the human body and monitoring its level is meaningful due to the relationship between its level and diseases. A fluorescent sensor (CMB) based on coumarin was designed and its ability for detecting hydrogen peroxide by fluorescence signals was also studied. The CMB showed an approximate 25-fold fluorescence enhancement after adding H2O2 due to the interaction between the CMB and H2O2 and had the potential for detecting physiological H2O2. It also showed good biocompatibility and permeability, allowing it to penetrate cell membranes and zebrafish tissues, thus it can perform fluorescence imaging of H2O2 in living cells and zebrafish. This probe is a promising tool for monitoring the level of H2O2 in related physiological and pathological research.

A highly selective turn-on fluorescent sensor for fluoride and its application in imaging of living cells

2014 ◽  
Vol 38 (12) ◽  
pp. 6198-6204 ◽  
Author(s):  
Jiun-Ting Yeh ◽  
Parthiban Venkatesan ◽  
Shu-Pao Wu
Keyword(s):  
Fluorescent Probe ◽  
Fluorescence Enhancement ◽  
Fluorescent Sensor ◽  
Living Cells ◽  
Green Fluorescence ◽  
Turn On ◽  
Highly Sensitive

A highly sensitive and selective fluorescent probe (FS) is based on a fluoride-specific desilylation reaction to yield a significant green fluorescence enhancement.

Mitochondria-Targeted Fluorescent Probe for Imaging Hydrogen Peroxide in Living Cells

2015 ◽  
Vol 88 (2) ◽  
pp. 1455-1461 ◽  
Author(s):  
Jian Xu ◽  
Yan Zhang ◽  
Hui Yu ◽  
Xudong Gao ◽  
Shijun Shao
Keyword(s):  
Hydrogen Peroxide ◽  
Fluorescent Probe ◽  
Living Cells

A practical pH-compatible fluorescent sensor for hydrazine in soil, water and living cells

The Analyst ◽  
2020 ◽  
Vol 145 (22) ◽  
pp. 7380-7387 ◽  
Author(s):  
Huming Yan ◽  
Fangjun Huo ◽  
Yongkang Yue ◽  
Jianbin Chao ◽  
Caixia Yin
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Respiratory Tract ◽  
Human Body ◽  
Water Solubility ◽  
Fluorescent Sensor ◽  
Living Cells ◽  
Human Organs ◽  
System P ◽  
The Central Nervous System

The excellent water solubility of hydrazine (N2H4) allows it to easily invade the human body through the skin and respiratory tract, thereby damaging human organs and the central nervous system.

A lysosome targetable fluorescent probe for endogenous imaging of hydrogen peroxide in living cells

2017 ◽  
Vol 53 (26) ◽  
pp. 3701-3704 ◽  
Author(s):  
Shahi Imam Reja ◽  
Muskan Gupta ◽  
Neha Gupta ◽  
Vandana Bhalla ◽  
Puja Ohri ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Fluorescent Probe ◽  
Living Cells

A lysosome targetable naphthalimide based fluorescent probe has been designed and synthesized for selective imaging of H2O2 in different cells, tissues and in vivo models.

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