scholarly journals Metabolomic Profiling and Toxicokinetics Modeling to Assess the Effects of the Pharmaceutical Diclofenac in the Aquatic Invertebrate Hyalella azteca

2021 ◽  
Author(s):  
Qiuguo Fu ◽  
Andreas Scheidegger ◽  
Endre Laczko ◽  
Juliane Hollender
Keyword(s):  
Hyalella Azteca ◽  
Aquatic Invertebrate ◽  
Metabolomic Profiling

Authenticity Assessment of Botanicals and Food Products using Metabolomic Profiling of Accurate Mass LC-MS/MS Data

Planta Medica ◽  
2013 ◽  
Vol 79 (05) ◽  
Author(s):  
A Schreiber ◽  
YY Zou ◽  
J Wong
Keyword(s):  
Food Products ◽  
Accurate Mass ◽  
Authenticity Assessment ◽  
Metabolomic Profiling

Transcriptomic and Metabolomic Profiling of Chicken Adipose Tissue: Dual Purpose Benefit for Human Obesity and Poultry Production

2018 ◽  
Vol 6 (2) ◽  
pp. 96-102
Author(s):  
Ronique C. Beckford ◽  
Eric D. Tague ◽  
Shawn R. Campagna ◽  
Brynn H. Voy
Keyword(s):  
Adipose Tissue ◽  
Poultry Production ◽  
Human Obesity ◽  
Dual Purpose ◽  
Metabolomic Profiling

Lac Dufault sediment core trace metal distribution, bioavailability and toxicity to Hyalella azteca

2006 ◽  
Vol 139 (3) ◽  
pp. 532-540 ◽  
Author(s):  
Monica Nowierski ◽  
D. George Dixon ◽  
Uwe Borgmann
Keyword(s):  
Trace Metal ◽  
Sediment Core ◽  
Hyalella Azteca ◽  
Metal Distribution ◽  
Trace Metal Distribution

Metabolomic profiling of single enlarged lysosomes

2021 ◽  
Author(s):  
Hongying Zhu ◽  
Qianqian Li ◽  
Tiepeng Liao ◽  
Xiang Yin ◽  
Qi Chen ◽  
...  
Keyword(s):  
Metabolomic Profiling

Metabolomic Profiling of Active and Inactive Liver Cystic Echinococcosis

Acta Tropica ◽  
2021 ◽  
pp. 105985
Author(s):  
Turkmen T. Ciftci ◽  
Samiye Yabanoglu-Ciftci ◽  
Emre Unala Devrim Akinci ◽  
Ipek Baysal ◽  
Gokhan Yuce ◽  
...  
Keyword(s):  
Cystic Echinococcosis ◽  
Metabolomic Profiling

scholarly journals Metabolic Evaluation of Urine from Patients Diagnosed with High Grade (HG) Bladder Cancer by SPME-LC-MS Method

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2194
Author(s):  
Kamil Łuczykowski ◽  
Natalia Warmuzińska ◽  
Sylwia Operacz ◽  
Iga Stryjak ◽  
Joanna Bogusiewicz ◽  
...  
Keyword(s):  
Thin Film ◽  
Bladder Cancer ◽  
High Performance ◽  
Biomarker Discovery ◽  
Solid Phase ◽  
Biological Fluids ◽  
Reversed Phase ◽  
Control Group ◽  
Metabolic Evaluation ◽  
Metabolomic Profiling

Bladder cancer (BC) is a common malignancy of the urinary system and a leading cause of death worldwide. In this work, untargeted metabolomic profiling of biological fluids is presented as a non-invasive tool for bladder cancer biomarker discovery as a first step towards developing superior methods for detection, treatment, and prevention well as to further our current understanding of this disease. In this study, urine samples from 24 healthy volunteers and 24 BC patients were subjected to metabolomic profiling using high throughput solid-phase microextraction (SPME) in thin-film format and reversed-phase high-performance liquid chromatography coupled with a Q Exactive Focus Orbitrap mass spectrometer. The chemometric analysis enabled the selection of metabolites contributing to the observed separation of BC patients from the control group. Relevant differences were demonstrated for phenylalanine metabolism compounds, i.e., benzoic acid, hippuric acid, and 4-hydroxycinnamic acid. Furthermore, compounds involved in the metabolism of histidine, beta-alanine, and glycerophospholipids were also identified. Thin-film SPME can be efficiently used as an alternative approach to other traditional urine sample preparation methods, demonstrating the SPME technique as a simple and efficient tool for urinary metabolomics research. Moreover, this study’s results may support a better understanding of bladder cancer development and progression mechanisms.

scholarly journals Plasma metabolomic profiling in workers with noise-induced hearing loss: a pilot study

2021 ◽  
Author(s):  
Long Miao ◽  
Boshen Wang ◽  
Juan Zhang ◽  
Lihong Yin ◽  
Yuepu Pu
Keyword(s):  
Hearing Loss ◽  
Pilot Study ◽  
Noise Induced Hearing Loss ◽  
Metabolomic Profiling

The contribution of detoxification pathways to pyrethroid resistance in Hyalella azteca

2021 ◽  
Vol 284 ◽  
pp. 117158
Author(s):  
Courtney Y. Fung ◽  
Kun Yan Zhu ◽  
Kaley Major ◽  
Helen C. Poynton ◽  
Kara E. Huff Hartz ◽  
...  
Keyword(s):  
Pyrethroid Resistance ◽  
Hyalella Azteca ◽  
Detoxification Pathways
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