Harvest Strategies for Optimization of the Content of Bioactive Alkamides and Caffeic Acid Derivatives in Aerial Parts and in Roots ofEchinacea purpurea

The aerial parts of Scorzonera aristata Ramond ex DC., collected in the South Tyrolean Dolomites, yielded the flavonoids quercetin 3- O-glucoside, rutin, and isoorientin, and the caffeic acid derivatives chlorogenic acid, 4,5-dicaffeoyl quinic acid, and 3,5-dicaffeoyl quinic acid. Sub-aerial parts contained caffeic acid methyl ester, 3,5-dicaffeoyl quinic acid, and the triterpenes 3α-hydroxyolean-5-ene, lupeol, and magnificol. Chemosystematic implications of the isolated compounds are discussed briefly.

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Caffeic acid derivatives isolated from the aerial parts of Galinsoga parviflora and their effect on inhibiting oxidative burst in human neutrophils

Phytochemistry Letters ◽

10.1016/j.phytol.2016.05.007 ◽

2016 ◽

Vol 16 ◽

pp. 303-310 ◽

Cited By ~ 9

Author(s):

Marta K. Dudek ◽

Łukasz Dudkowski ◽

Agnieszka Bazylko ◽

Sławomir Kaźmierski ◽

Anna K. Kiss

Keyword(s):

Caffeic Acid ◽

Oxidative Burst ◽

Human Neutrophils ◽

Caffeic Acid Derivatives ◽

Aerial Parts

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The determination of the caffeic acid derivatives of Echinacea purpurea aerial parts under various extraction conditions by supercritical fluid extraction (SFE)

The Journal of Supercritical Fluids ◽

10.1016/j.supflu.2014.02.014 ◽

2014 ◽

Vol 89 ◽

pp. 128-136 ◽

Cited By ~ 13

Author(s):

Nevzat Konar ◽

Sevim Dalabasmaz ◽

Ender Sinan Poyrazoglu ◽

Nevzat Artik ◽

Ahmet Colak

Keyword(s):

Caffeic Acid ◽

Supercritical Fluid Extraction ◽

Supercritical Fluid ◽

Echinacea Purpurea ◽

Fluid Extraction ◽

Caffeic Acid Derivatives ◽

Aerial Parts ◽

Derivatives Of

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Chemical analysis of some Ocimum basilicum medicinal teas

Romanian Journal of Pharmaceutical Practice ◽

10.37897/rjphp.2021.3.6 ◽

2021 ◽

Vol 14 (3) ◽

pp. 145-148

Author(s):

Daniela BENEDEC ◽

◽

Diana ROZSA (RUS) ◽

Daniela HANGANU ◽

Ilioara ONIGA ◽

...

Keyword(s):

Chemical Composition ◽

Phenolic Compounds ◽

Caffeic Acid ◽

Ocimum Basilicum ◽

Caffeic Acid Derivatives ◽

Aromatic Character ◽

Aerial Parts ◽

Three Samples ◽

Therapeutic Properties ◽

Layer Chromatography

Objectives. Ocimum basilicum is one of the widespread medicinal plants, widely used due to its multiple therapeutic properties (antimicrobial, antiviral, hypoglycemic, antispasmodic, anti-inflammatory, carminative, stomachic, antioxidant, analgesic, etc.), as well as its specific aromatic character. The aim of this study was to comparatively investigate the chemical composition (flavonoids, caffeic acid derivatives, tannins, essential oil) of the aerial parts of some Romanian medicinal teas of Ocimum basilicum. Materials and methods. The content of flavonoids, phenolic acids and tannins in three samples of O. basilicum tea were determined spectrophotometrically. Identification of important phenolic compounds (rutin, isoquercitrin chlorogenic acid and caffeic acid) was performed by thin layer chromatography (TLC). The essential oils were obtained by hydrodistillation method. Outcomes and conclusions. Following the quantitative determinations performed, it can be seen that the basil samples are rich in active principles, and their use for the treatment of some diseases can be justified.

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Increasing medicinal and phytochemical compounds of coneflower (Echinacea purpurea L.) as affected by NO3−/NH4+ ratio and perlite particle size in hydroponics

Scientific Reports ◽

10.1038/s41598-021-94589-4 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Fatemeh Ahmadi ◽

Abbas Samadi ◽

Ebrahim Sepehr ◽

Amir Rahimi ◽

Sergey Shabala

Keyword(s):

Particle Size ◽

Caffeic Acid ◽

Culture Media ◽

Chemical Compounds ◽

Echinacea Purpurea ◽

Hydroponic Culture ◽

Peat Moss ◽

Root Extract ◽

Caffeic Acid Derivatives ◽

Phytochemical Compounds

AbstractMedicinal plants are considered as one of the most important sources of chemical compounds, so preparing a suitable culture media for medicinal plant growth is a critical factor. The present study is aimed to improve the caffeic acid derivatives and alkylamides percentages of Echinacea purpurea root extract in hydroponic culture media with different perlite particle size and NO3−/NH4+ ratios. Perlite particle size in the growing media was varied as very coarse perlite (more than 2 mm), coarse perlite (1.5–2 mm), medium perlite (1–1.5 mm), fine perlite (0.5–1 mm), and very fine perlite (less than 0.5 mm) in different ratios to peat moss (including pure perlite, 50:50 v/v, 30:70 v/v, and pure peat moss). Two NO3−/NH4+ ratios (90:10 and 70:30) were tested in each growing media. All phytochemical analyses were performed according to standard methods using high performance liquid chromatography (HPLC). It was found that the E. purpurea grown in the medium containing very fine-grade perlite with 50:50 v/v perlite to peat moss ratio had the maximum caffeic acid derivatives, including chicoric acid (17 mg g−1 DW), caftaric acid (6.3 mg g−1 DW), chlorogenic acid (0.93 mg g−1 DW), cynarin (0.84 mg g−1 DW), and echinacoside (0.73 mg g−1 DW), as well as, alkylamides (54.21%). The percentages of these phytochemical compounds increased by decreasing perlite particle size and increasing of NO3−/NH4+ ratio. The major alkylamide in the E. purpurea root extract was dodeca-2E, 4E, 8Z-10 (E/Z)-tetraenoic acid isobutylamide in all treatments, ranging from 31.12 to 54.21% of total dry weight. It can be concluded that optimizing hydroponic culture media and nutrient solution has significant effects on E. purpurea chemical compounds.

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Stem Lettuce and Its Metabolites: Does the Variety Make Any Difference?

Foods ◽

10.3390/foods10010059 ◽

2020 ◽

Vol 10 (1) ◽

pp. 59

Author(s):

Janusz Malarz ◽

Klaudia Michalska ◽

Anna Stojakowska

Keyword(s):

Chemical Composition ◽

Plant Material ◽

Methanolic Extract ◽

Sesquiterpene Lactones ◽

Scavenging Activity ◽

Nmr Analysis ◽

Caffeic Acid Derivatives ◽

Aerial Parts ◽

Dpph Scavenging Activity ◽

Dpph Scavenging

The objective of the present study was to characterize chemical composition of hitherto unexamined aerial parts of Lactuca sativa var. angustana cv. Grüner Stern. In contrast to leafy and head varieties of the lettuces, asparagus lettuce grown in Europe is much less studied. Fractionation of a methanolic extract from leaves of L. sativa cv. Grüner Stern, supported with HPLC/DAD and 1H NMR analysis, led to the isolation and/or identification of numerous terpenoid and phenolic compounds, including five apocarotenoids—(-)-loliolide, (+)-dehydrovomifoliol, blumenol A, (6S,9S)-vomifoliol, and corchoionoside C; three sesquiterpene lactones; two lignans—((+)-syringaresinol and its 4-O-β-glucoside); five caffeic acid derivatives; and three flavonoids. Some of the compounds, to the best of our knowledge, have never been isolated from L. sativa before. Moreover, monolignols, phenolic acids and a tryptophan-derived alkaloid were found in the analyzed plant material. Stems, leaves and shoot tips of the asparagus lettuce were examined to assess their phenolics and sesquiterpene lactone content as well as DPPH scavenging activity. Another stem lettuce—L. sativa var. angustana cv. Karola, two cultivars of leafy lettuces and one species of wild lettuce—L. serriola, were also examined as a reference material using HPLC/DAD. The results have been discussed regarding our previous studies and the literature data available.

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