Matrix Metalloproteinase-Responsive Mesoporous Silica Nanoparticles Cloaked with Cleavable Protein for “Self-Actuating” On-Demand Controlled Drug Delivery for Cancer Therapy

2020 ◽  
Vol 3 (8) ◽  
pp. 4987-4999 ◽  
Author(s):  
Kalpesh Vaghasiya ◽  
Eupa Ray ◽  
Ankur Sharma ◽  
Om Prakash Katare ◽  
Rahul Kumar Verma
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Matrix Metalloproteinase ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Controlled Drug Delivery ◽  
On Demand

Wetting transition in nanochannels for biomimetic free-blocking on-demand drug transport

2018 ◽  
Vol 6 (39) ◽  
pp. 6269-6277 ◽  
Author(s):  
Yaya Cheng ◽  
Xiangyu Jiao ◽  
Liang Zhao ◽  
Yang Liu ◽  
Fang Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery System ◽  
Delivery System ◽  
Drug Transport ◽  
Mesoporous Silica Nanoparticles ◽  
Wetting Transition ◽  
On Demand ◽  
Inner Surface

Inspired by aquaporins in nature, herein, a biomimetic free-blocking on-demand drug delivery system is proposed, which is constructed by controlling the wettability of the inner surface of nanochannels on mesoporous silica nanoparticles (MSNs).

A soft–hard template approach towards hollow mesoporous silica nanoparticles with rough surfaces for controlled drug delivery and protein adsorption

2015 ◽  
Vol 3 (31) ◽  
pp. 6480-6489 ◽  
Author(s):  
Haijiao Zhang ◽  
Huijuan Xu ◽  
Minghong Wu ◽  
Yufang Zhong ◽  
Donghai Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Protein Adsorption ◽  
Rough Surfaces ◽  
Mesoporous Silica Nanoparticles ◽  
Controlled Drug Delivery ◽  
Hard Template ◽  
Hollow Mesoporous Silica

Novel hollow mesoporous silica nanoparticles (HMSNs) with rough surfaces have been successfully prepared using a facile soft–hard template route.

Cisplatin and doxorubicin dual-loaded mesoporous silica nanoparticles for controlled drug delivery

RSC Advances ◽  
2016 ◽  
Vol 6 (96) ◽  
pp. 94160-94169 ◽  
Author(s):  
Hanwen Li ◽  
Huijuan Yu ◽  
Caiying Zhu ◽  
Jianhua Hu ◽  
Ming Du ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Synergistic Effect ◽  
Silica Nanoparticles ◽  
Therapeutic Efficacy ◽  
Mesoporous Silica Nanoparticles ◽  
Controlled Drug Delivery

Multicomponent therapeutic platforms have been proposed to minimize dosage of each drug and reduce toxicity, leading to achieving a synergistic effect and maximizing therapeutic efficacy.

scholarly journals Synthesis of surface capped mesoporous silica nanoparticles for pH-stimuli responsive drug delivery applications

MedChemComm ◽  
2017 ◽  
Vol 8 (9) ◽  
pp. 1797-1805 ◽  
Author(s):  
Madhappan Santha Moorthy ◽  
Subramanian Bharathiraja ◽  
Panchanathan Manivasagan ◽  
Kang Dae Lee ◽  
Junghwan Oh
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Carrier ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Drug Delivery Applications

Herein, we propose a “host–guest” complexation-based mesoporous silica drug carrier, MSNs@Mela@TTM, for pH-responsive drug delivery applications in cancer therapy.

scholarly journals Highlights in Mesoporous Silica Nanoparticles as a Multifunctional Controlled Drug Delivery Nanoplatform for Infectious Diseases Treatment

2020 ◽  
Vol 37 (10) ◽  
Author(s):  
Gabriela Corrêa Carvalho ◽  
Rafael Miguel Sábio ◽  
Tais de Cássia Ribeiro ◽  
Andreia Sofia Monteiro ◽  
Daniela Vassalo Pereira ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Infectious Diseases ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Controlled Drug Delivery
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