Facile Formation of PAMAM Dendrimer Nanoclusters for Enhanced Gene Delivery and Cancer Gene Therapy

2021 ◽  
Vol 4 (9) ◽  
pp. 7168-7175
Author(s):  
Shewaye Lakew Mekuria ◽  
Jin Li ◽  
Cong Song ◽  
Yue Gao ◽  
Zhijun Ouyang ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Gene Delivery ◽  
Pamam Dendrimer ◽  
Cancer Gene Therapy ◽  
Cancer Gene

scholarly journals Light-induced adenovirus gene transfer, an efficient and specific gene delivery technology for cancer gene therapy

2002 ◽  
Vol 9 (4) ◽  
pp. 365-371 ◽  
Author(s):  
Anders Høgset ◽  
Birgit Øvstebø Engesæter ◽  
Lina Prasmickaite ◽  
Kristian Berg ◽  
Øystein Fodstad ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Gene Transfer ◽  
Gene Delivery ◽  
Cancer Gene Therapy ◽  
Specific Gene ◽  
Cancer Gene ◽  
Delivery Technology

scholarly journals Transcriptional Targeting in Cancer Gene Therapy

2003 ◽  
Vol 2003 (2) ◽  
pp. 110-137 ◽  
Author(s):  
Tracy Robson ◽  
David G. Hirst
Keyword(s):  
Gene Therapy ◽  
Gene Delivery ◽  
Cancer Gene Therapy ◽  
Cancer Gene ◽  
Cancer Treatments ◽  
Transcriptional Targeting ◽  
Exogenous Agents ◽  
Therapeutic Research ◽  
Systemic Gene Delivery ◽  
Near Future

Cancer gene therapy has been one of the most exciting areas of therapeutic research in the past decade. In this review, we discuss strategies to restrict transcription of transgenes to tumour cells. A range of promoters which are tissue-specific, tumour-specific, or inducible by exogenous agents are presented. Transcriptional targeting should prevent normal tissue toxicities associated with other cancer treatments, such as radiation and chemotherapy. In addition, the specificity of these strategies should provide improved targeting of metastatic tumours following systemic gene delivery. Rapid progress in the ability to specifically control transgenes will allow systemic gene delivery for cancer therapy to become a real possibility in the near future.

Pancreatic cancer: gene therapy approaches and gene delivery systems

2009 ◽  
Vol 10 (1) ◽  
pp. 73-88 ◽  
Author(s):  
Jin Xu ◽  
Chen Jin ◽  
Sijie Hao ◽  
Guopei Luo ◽  
Deliang Fu
Keyword(s):  
Pancreatic Cancer ◽  
Gene Therapy ◽  
Gene Delivery ◽  
Cancer Gene Therapy ◽  
Delivery Systems ◽  
Cancer Gene

Viral and Nonviral Gene Delivery Vectors for Cancer Gene Therapy

1998 ◽  
Vol 22 (5) ◽  
pp. 445-454 ◽  
Author(s):  
Richard J. Cristiano ◽  
Bo Xu ◽  
Dao Nguyen ◽  
Guido Schumacher ◽  
Masafumi Kataoka ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Gene Delivery ◽  
Cancer Gene Therapy ◽  
Nonviral Gene Delivery ◽  
Cancer Gene ◽  
Gene Delivery Vectors

A novel receptor-targeted gene delivery system for cancer gene therapy

1999 ◽  
Vol 42 (2) ◽  
pp. 216-224 ◽  
Author(s):  
Peikun Tian ◽  
Shengjun Ren ◽  
Changchun Ren ◽  
Qingshan Teng ◽  
Shumin Qu ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Gene Delivery ◽  
Delivery System ◽  
Cancer Gene Therapy ◽  
Cancer Gene ◽  
Gene Delivery System ◽  
Targeted Gene Delivery

Dextranated poly(urethane amine)s designed for systemic gene delivery in ovarian cancer therapy

2017 ◽  
Vol 5 (30) ◽  
pp. 6119-6127 ◽  
Author(s):  
Jie Zhao ◽  
Fei Han ◽  
Peng Zhao ◽  
Xuejun Wen ◽  
Chao Lin
Keyword(s):  
Ovarian Cancer ◽  
Gene Therapy ◽  
Cancer Therapy ◽  
Gene Delivery ◽  
Cancer Gene Therapy ◽  
Cancer Gene ◽  
Systemic Gene Delivery

Dextranated poly(urethane amine)s can be designed for robust ovarian cancer gene therapy.

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