A novel receptor-targeted gene delivery system for cancer gene therapy

1999 ◽  
Vol 42 (2) ◽  
pp. 216-224 ◽  
Author(s):  
Peikun Tian ◽  
Shengjun Ren ◽  
Changchun Ren ◽  
Qingshan Teng ◽  
Shumin Qu ◽  
...  
2005 ◽  
Vol 4 (6) ◽  
pp. 637-643 ◽  
Author(s):  
Guy Zuber ◽  
Christian D. Muller ◽  
Jean-Paul Behr

Progress in the design of gene delivery system is vital for cancer gene therapy since many physiological and intracellular barriers remain. We have developed a technology for condensing genes into nanometric delivery systems. In this paper, we present a novel strategy for decorating 30 nm DNA particles with folic acid for cancer cell recognition. Physicochemical and biological experiments show that these DNA complexes selectively bind to cells expressing the corresponding folic acid receptor.


2017 ◽  
Vol 5 (6) ◽  
pp. 1315-1327 ◽  
Author(s):  
Jiao Tan ◽  
Huiyuan Wang ◽  
Fan Xu ◽  
Yingzhi Chen ◽  
Meng Zhang ◽  
...  

A γ-PGA-based GGT-targeting and surface camouflage strategy for constructing a ternary layer-by-layer self-assembly gene delivery system.


2002 ◽  
Vol 9 (4) ◽  
pp. 365-371 ◽  
Author(s):  
Anders Høgset ◽  
Birgit Øvstebø Engesæter ◽  
Lina Prasmickaite ◽  
Kristian Berg ◽  
Øystein Fodstad ◽  
...  

2000 ◽  
Vol 7 (2) ◽  
pp. 269-274 ◽  
Author(s):  
Kazuyuki Yazawa ◽  
Minoru Fujimori ◽  
Jun Amano ◽  
Yasunobu Kano ◽  
Shun'ichiro Taniguchi

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