Protein-Gated Upconversion Nanoparticle-Embedded Mesoporous Silica Nanovehicles via Diselenide Linkages for Drug Release Tracking in Real Time and Tumor Chemotherapy

2021 ◽  
Author(s):  
Hua Yan ◽  
Jiangtao Dong ◽  
Xuan Huang ◽  
Xuezhong Du
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Real Time

Chitosan-Gated Fluorescent Mesoporous Silica Nanocarriers for the Real-Time Monitoring of Drug Release

Langmuir ◽  
2020 ◽  
Vol 36 (24) ◽  
pp. 6749-6756 ◽  
Author(s):  
Yu Chen ◽  
Weipeng Lu ◽  
Yanchuan Guo ◽  
Yi Zhu ◽  
Yeping Song
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Real Time ◽  
Real Time Monitoring ◽  
The Real

Real-time imaging of intracellular drug release from mesoporous silica nanoparticles based on fluorescence resonance energy transfer

2014 ◽  
Vol 2 (27) ◽  
pp. 4379-4386 ◽  
Author(s):  
Jun Wang ◽  
Peng Pei Gao ◽  
Xiao Xi Yang ◽  
Ting Ting Wang ◽  
Jian Wang ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Drug Release ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Real Time ◽  
Fluorescence Resonance Energy Transfer ◽  
Mesoporous Silica Nanoparticles ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Fluorescence Resonance

A multifunctional nanodevice is designed based on doxorubicin (DOX)-loaded green fluorescent mesoporous silica nanoparticles (FMSN) conjugated with folic acid (FA). Real-time monitoring of intracellular drug release based on fluorescence resonance energy transfer is achieved.

Design of a versatile nanocomposite for ‘seeing’ drug release and action behavior

2015 ◽  
Vol 3 (43) ◽  
pp. 8449-8458 ◽  
Author(s):  
Yu Zhang ◽  
Tingting Shen ◽  
Xia Deng ◽  
Yufei Ma ◽  
Lina Wang ◽  
...  
Keyword(s):  
Rare Earth ◽  
Drug Release ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Real Time ◽  
Mesoporous Silica Nanoparticles ◽  
Magnetic Core ◽  
New Method ◽  
Rare Earth Complex ◽  
Real Time Monitoring

To design a new method for ‘seeing’ drug release and action behavior, we combined a rare-earth complex with a magnetic-core-coated phenyl mesoporous silica nanoparticles matrix, taking advantage of the drug coordination for real-time monitoring.

scholarly journals Real-Time Monitoring of ATP-Responsive Drug Release Using Mesoporous-Silica-Coated Multicolor Upconversion Nanoparticles

ACS Nano ◽  
2015 ◽  
Vol 9 (5) ◽  
pp. 5234-5245 ◽  
Author(s):  
Jinping Lai ◽  
Birju P. Shah ◽  
Yixiao Zhang ◽  
Letao Yang ◽  
Ki-Bum Lee
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Real Time ◽  
Upconversion Nanoparticles ◽  
Real Time Monitoring

Dual-responsive mesoporous silica nanoparticles coated with carbon dots and polymers for drug encapsulation and delivery

Nanomedicine ◽  
2020 ◽  
Vol 15 (25) ◽  
pp. 2447-2458
Author(s):  
Xiaona Li ◽  
Shun Hu ◽  
Zhe Lin ◽  
Jie Yi ◽  
Xue Liu ◽  
...  
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Real Time ◽  
Fluorescence Intensity ◽  
Carbon Dots ◽  
Mesoporous Silica Nanoparticles ◽  
Aldehyde Group ◽  
Real Time Monitoring ◽  
Dual Responsive

Aim: Smart mesoporous silica nanoparticles (MSNs) coated with carbon dots (CDs) and poly(N-vinylcaprolactam) (PNVCL) as a mixed shell (CDs/PNVCL polymer grafted MSNs) were prepared for pH-trigged anticancer drug release and real-time monitoring. Materials & methods: The amino-terminated PNVCL and amino-rich CDs were grafted onto the surface of aldehyde group functionalized MSNs through Schiff base reaction. Doxorubicin (DOX) was loaded into the prepared nanoparticles. Results: DOX could be quickly released in the tumor environment, leading to cell apoptosis. The linear fit between the percentage of released DOX and the fluorescence intensity of CDs indicated that the change in fluorescence intensity could be used to monitor drug release in real time. Conclusion: The as-prepared CDs/PNVCL polymer grafted MSNs are promising candidates for integrating controllable release and real-time monitoring in cancer treatment.

Sign in / Sign up

Export Citation Format

Share Document