Small-Molecule Porphyrin-Based Organic Nanoparticles with Remarkable Photothermal Conversion Efficiency for in Vivo Photoacoustic Imaging and Photothermal Therapy

2019 ◽  
Vol 11 (24) ◽  
pp. 21408-21416 ◽  
Author(s):  
Fengshou Wu ◽  
Li Chen ◽  
Liangliang Yue ◽  
Kai Wang ◽  
Kai Cheng ◽  
...  
Nanoscale ◽  
2018 ◽  
Vol 10 (2) ◽  
pp. 825-831 ◽  
Author(s):  
Lile Dong ◽  
Guanming Ji ◽  
Yu Liu ◽  
Xia Xu ◽  
Pengpeng Lei ◽  
...  

The novel Cu–Ag2S/PVP NPs with high photothermal conversion efficiency could be employed as effective photoacoustic imaging guided photothermal therapy agents.


2019 ◽  
Vol 7 (25) ◽  
pp. 3950-3957 ◽  
Author(s):  
Zikang Chen ◽  
Qi Xia ◽  
Yuping Zhou ◽  
Xipan Li ◽  
Li Qi ◽  
...  

TPTHM NPs are candidates for PAI/PTT agents due to their NIR absorption, good biocompatibility, high photostability and photothermal conversion efficiency (38%).


2017 ◽  
Vol 1 (8) ◽  
pp. 1556-1562 ◽  
Author(s):  
Xiaolei Cai ◽  
Jie Liu ◽  
Weng Heng Liew ◽  
Yukun Duan ◽  
Junlong Geng ◽  
...  

We report organic nanoparticles for efficient photoacoustic imaging and photothermal therapy, based on the small molecule BTPETTQ which has a propeller structure and a donor–acceptor–donor configuration.


2018 ◽  
Vol 54 (99) ◽  
pp. 13989-13992 ◽  
Author(s):  
Changhui Fu ◽  
Longfei Tan ◽  
Xiangling Ren ◽  
Qiong Wu ◽  
Haibo Shao ◽  
...  

Interlayer-expanded MoS2 nanosheets with a value of 0.94 nm are demonstrated to show a high photothermal conversion efficiency of ∼62%.


2020 ◽  
Vol 44 (12) ◽  
pp. 4850-4857 ◽  
Author(s):  
Xiuhui Yin ◽  
Xianglong Li ◽  
Chunling Zhu ◽  
Xucong Lin ◽  
Zenghong Xie

By a facile protein-based biomineralization method, Ag2Se@BSA-RGD QDs with ultrasmall sizes were obtained and exhibited a high fluorescence quantum yield, strong photoacoustic signals and promising photothermal conversion efficiency.


2019 ◽  
Vol 7 (14) ◽  
pp. 2247-2251 ◽  
Author(s):  
Lu Li ◽  
Qingzhu Yang ◽  
Lei Shi ◽  
Nannan Zheng ◽  
Zeyu Li ◽  
...  

Novel phthalocyanine molecule 4OCSPC with deep NIR absorbance showed excellent photothermal therapy property for cancer cells.


Materials ◽  
2018 ◽  
Vol 11 (9) ◽  
pp. 1776 ◽  
Author(s):  
Wenhao Dai ◽  
Haifeng Dong ◽  
Xueji Zhang

Theranostic platforms integrating imaging diagnostic and therapeutic interventions into a single nanoplatform have attracted considerable attention for cancer-individualized therapies. However, their uncertain stability, complex pharmacokinetics, and intrinsic toxicology of multiple components hinder their practical application in clinical research. In this paper, stable and high-concentration molybdenum carbide quantum dots (Mo2C QDs) with a diameter of approximately 6 nm and a topographic height of about 1.5 nm were synthesized using a facile sonication-assisted liquid-phase exfoliation approach. The prepared Mo2C QDs exhibited a strong near-infrared (NIR) absorbance with a high molar extinction coefficient of 4.424 Lg−1cm−1 at 808 nm, a high photothermal conversion efficiency of 42.9%, and showed excellent performance on photoacoustic imaging. The Mo2C QDs had high stability and highly biocompatibility, with low cytotoxicity. Under NIR irradiation, a remarkable in vitro and in vivo therapeutic effect was obtained. Such a stable and biocompatible all-in-one theranostic nanoagent generated by facile synthesis that combines promising imaging guidance and effective tumor ablation properties may hold great potential for theranostic nanomedicine.


2014 ◽  
Vol 26 (48) ◽  
pp. 8210-8216 ◽  
Author(s):  
Mei Chen ◽  
Shaoheng Tang ◽  
Zhide Guo ◽  
Xiaoyong Wang ◽  
Shiguang Mo ◽  
...  

Nanoscale ◽  
2021 ◽  
Author(s):  
Qing Xu ◽  
Danyang Li ◽  
Haijun Zhou ◽  
Biaoqi Chen ◽  
Junlei Wang ◽  
...  

We describe the synthesis of MnO2-coated porous Pt@CeO2 core–shell nanostructures (Pt@CeO2@MnO2) as a new theranostic nano-platform. The porous Pt cores endow the core–shell nanostructures with high photothermal conversion efficiency (80%)...


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