Phenazine Natural Products:  Biosynthesis, Synthetic Analogues, and Biological Activity

Mangrove plants are specialised plants that grow in the tidal coasts of tropic and subtropic regions of the world. Their unique ecology and traditional medicinal uses of mangrove plants have attracted the attention of researchers over the years, and as a result, reports on biological activity of mangrove plants have increased significantly in recent years. This review has been set out to compile and appraise the results on antinociceptive, anti-inflammatory, and antipyretic activity of mangrove plants. While the Web of Knowledge, Google Scholar, and PubMed were the starting points to gather information, other pieces of relevant published literature were also adequately explored for this purpose. A total of 29 reports on 17 plant species have been found to report such activities. While 19 reports were on the biological activity of the crude extracts, 10 reports identified the active compound(s) of various chemical classes of natural products including terpenes, steroids, and flavonoids. This review finds that antinociceptive, anti-inflammatory, and antipyretic activity appears to be widespread in mangrove plants.

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Directed aromatic functionalization in natural-product synthesis: Fredericamycin A, nothapodytine B, and topopyrones B and D

Beilstein Journal of Organic Chemistry ◽

10.3762/bjoc.7.171 ◽

2011 ◽

Vol 7 ◽

pp. 1475-1485 ◽

Cited By ~ 2

Author(s):

Charles Dylan Turner ◽

Marco A Ciufolini

Keyword(s):

Natural Products ◽

Biological Activity ◽

Natural Product ◽

Natural Product Synthesis ◽

Fredericamycin A

This is a review of our efforts toward the synthesis of a group of natural products that display noteworthy biological activity: Fredericamycin A, nothapodytine B, and topopyrones B and D. In each case, directed aromatic functionalization methodology greatly facilitated the assembly of the key molecular subunits.

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Copper complexes of glycyl-histidyl-lysine and two of its synthetic analogues: chemical behaviour and biological activity

Biochimica et Biophysica Acta (BBA) - General Subjects ◽

10.1016/s0304-4165(01)00127-1 ◽

2001 ◽

Vol 1526 (2) ◽

pp. 199-210 ◽

Cited By ~ 29

Author(s):

Chiara Conato ◽

Riccardo Gavioli ◽

Remo Guerrini ◽

Henryk Kozłowski ◽

Piotr Młynarz ◽

...

Keyword(s):

Biological Activity ◽

Copper Complexes ◽

Synthetic Analogues ◽

Chemical Behaviour

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Dry Column Chromatographic Procedure for Rapid Concentration of Biological Activity in Natural Products Fractionation

Journal of Pharmaceutical Sciences ◽

10.1002/jps.2600700329 ◽

1981 ◽

Vol 70 (3) ◽

pp. 329-331 ◽

Cited By ~ 3

Author(s):

Gerard C. Hokansonx ◽

Nancy J. Matyunas

Keyword(s):

Natural Products ◽

Biological Activity ◽

Chromatographic Procedure ◽

Products Fractionation ◽

Column Chromatographic

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Chemical and Functional Diversity of Natural Products from Plant Associated Endophytic Fungi

Natural Product Communications ◽

10.1177/1934578x0900401114 ◽

2009 ◽

Vol 4 (11) ◽

pp. 1934578X0900401 ◽

Cited By ~ 20

Author(s):

Vijay C. Verma ◽

Ravindra N. Kharwar ◽

Gary A. Strobel

Keyword(s):

Natural Products ◽

Biological Activity ◽

Functional Diversity ◽

Bioactive Compounds ◽

Endophytic Fungi ◽

Host Plants ◽

Fungal Endophytes ◽

Sources Identification ◽

Naturally Occurring

This review describes examples of naturally occurring bioactive compounds obtained from fungal endophytes from various host plants. The main topics addressed are sources, identification, biological activity, biosynthesis, and ecological and chemosystematic significance of those bioactive compounds whose sources were well defined.

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