A Journey fromn-Heptane to Liquid Transportation Fuels. 1. The Role of the Allylic Radical and Its Related Species in Aromatic Precursor Chemistry

2008 ◽  
Vol 22 (2) ◽  
pp. 945-953 ◽  
Author(s):  
Hongzhi R. Zhang ◽  
Eric G. Eddings ◽  
Adel F. Sarofim



2009 ◽  
Vol 37 (4) ◽  
pp. 778-782 ◽  
Author(s):  
Macarena Toll-Riera ◽  
Robert Castelo ◽  
Nicolás Bellora ◽  
M. Mar Albà

Genomes contain a large number of genes that do not have recognizable homologues in other species. These genes, found in only one or a few closely related species, are known as orphan genes. Their limited distribution implies that many of them are probably involved in lineage-specific adaptive processes. One important question that has remained elusive to date is how orphan genes originate. It has been proposed that they might have arisen by gene duplication followed by a period of very rapid sequence divergence, which would have erased any traces of similarity to other evolutionarily related genes. However, this explanation does not seem plausible for genes lacking homologues in very closely related species. In the present article, we review recent efforts to identify the mechanisms of formation of primate orphan genes. These studies reveal an unexpected important role of transposable elements in the formation of novel protein-coding genes in the genomes of primates.



2018 ◽  
Vol 37 (13) ◽  
pp. 2075-2085 ◽  
Author(s):  
Madison L. McCrea-Hendrick ◽  
Markus Bursch ◽  
Kelly L. Gullett ◽  
Leonard R. Maurer ◽  
James C. Fettinger ◽  
...  


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Renatas Krasauskas ◽  
Jūratė Skerniškytė ◽  
Julija Armalytė ◽  
Edita Sužiedėlienė

Abstract Background Acinetobacter baumannii is one of the most important opportunistic pathogens responsible for hospital acquired infections. It displays multi-drug resistance profile and has the ability to colonize surfaces and persist under harsh conditions. A. baumannii two-component signal transduction system BfmRS, consisting of response regulator BfmR and sensor kinase BfmS, has been implicated in the control of various virulence-related traits and has been suggested to act as a global modulator of A. baumannii physiology. Results Here, we assessed the role of BfmR regulator in pellicle formation and bacterial competition, features important for the establishment of A. baumannii in clinical environment. We show that BfmR is required for the pellicle formation of A. baumannii, as ΔbfmRS mutant lacked this phenotype. The loss of bfmRS also greatly reduced the secretion of A. baumannii Hcp protein, which is a component of T6SS secretion system. However, T6SS-mediated killing phenotype was not impaired in ΔbfmRS mutant. On the contrary, the same mutation resulted in the transcriptional activation of contact-dependent inhibition (CDI) system, which A. baumannii used to inhibit the growth of another clinical A. baumannii strain and a closely related species Acinetobacter baylyi. Conclusions The obtained results indicate that BfmR is not only required for the pellicle phenotype induction in A. baumannii, but also, due to the down-regulation of a CDI system, could allow the incorporation of other A. baumannii strains or related species, possibly increasing the likelihood of the pathogens’ survival.



RSC Advances ◽  
2015 ◽  
Vol 5 (108) ◽  
pp. 88876-88885 ◽  
Author(s):  
Jonathan M. Powell ◽  
Jamie Adcock ◽  
Sheng Dai ◽  
Gabriel M. Veith ◽  
Craig A. Bridges

An effective approach to increasing the reversible specific capacity of TiOF2 conversion electrodes is presented. The capacity increased greatly when the precursor was partially reduced before direct fluorination in a fluidized bed reactor.



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