Background:
Clinical characteristics and outcomes for patients with intracerebral hemorrhage and underlying chronic kidney disease (CKD) are not well determined. We hypothesized rate adverse events and in-hospital mortality is higher in patients with intracerebral hemorrhage and underlying renal disease.
Objective:
To determine the Outcomes for intracerebral hemorrhage stroke patients with renal failure as comorbidity in the United States
Methods:
We analyzed the data from Nationwide Inpatient Sample
(2009-2011)
for all intracerebral hemorrhage stroke patients with or without renal failure as comorbidity. Patients were identified using the International Classification of Disease, Ninth Revision. Baseline characteristics, in-hospital complications including myocardial infarction), sepsis, pneumonia, deep venous thrombosis, urinary tract infections, and discharge outcomes (mortality, minimal disability, and moderate-to-severe disability) were compared between the two groups. All in-hospital outcomes were analyzed after adjusting for potential confounders using multivariate analysis.
Results:
Of the
33521
patients with intracerebral hemorrhage stroke,
3899 (11.6%)
had renal failure as comorbidity. Patients with underlying renal disease were higher rates for in hospital complications like myocardial infarction
(3.64% versus 2.03%, P≤.0001)
, sepsis
(5.82% versus 3.14%, P≤.0001)
, pneumonia
(6.92% versus 5.18%, P≤.0001)
, deep venous thrombosis
(1.67 % versus 1.17%, P≤ .0.0078)
, urinary tract infections
(16.41% versus 15.08%, P≤ 0.0293)
and hypernatremia
(8.62% versus 4.98%, P≤ <.0001).
In multivariate analysis adjusted for baseline cormorbitdities and in hospital complications, intracerebral hemorrhage patients with underlying renal disease had higher in hospital mortality
(OR 1.146 (95% confidence interval (CI)
1.058- 1.240p-value=0.0008)
, while there is no statistically significant difference for minimal/moderate disability between two groups (
OR = 0.980 (95% CI
0.896- 1.072 p-value=0.6571).
Conclusions:
Intracerebral hemorrhage patients with underlying renal disease have higher rate of in hospital complications and mortality. Future prospective studies are indicated to study this finding.
Erratum to “Place as a predictor of health insurance coverage: A multivariate analysis of counties in the United States” [Health Place 34 (2015) 207–214]
