Near Infrared Laser-Induced Targeted Cancer Therapy Using Thermoresponsive Polymer Encapsulated Gold Nanorods

2014 ◽  
Vol 136 (20) ◽  
pp. 7317-7326 ◽  
Author(s):  
Zhenjiang Zhang ◽  
Jing Wang ◽  
Xin Nie ◽  
Tao Wen ◽  
Yinglu Ji ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Gold Nanorods ◽  
Near Infrared ◽  
Infrared Laser ◽  
Targeted Cancer Therapy ◽  
Thermoresponsive Polymer

A multifunctional near-infrared laser-triggered drug delivery system using folic acid conjugated chitosan oligosaccharide encapsulated gold nanorods for targeted chemo-photothermal therapy

2019 ◽  
Vol 7 (24) ◽  
pp. 3811-3825 ◽  
Author(s):  
Panchanathan Manivasagan ◽  
Seung Won Jun ◽  
Van Tu Nguyen ◽  
Nguyen Thanh Phong Truong ◽  
Giang Hoang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Folic Acid ◽  
Combination Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Infrared Laser ◽  
Chitosan Oligosaccharide

FA–COS–TGA–GNRs–DOX have been successfully designed as a drug delivery system for chemo-photothermal combination therapy.

PNIPAM Gel-Coated Gold Nanorods for Targeted Delivery Responding to a Near-Infrared Laser

2009 ◽  
Vol 20 (2) ◽  
pp. 209-212 ◽  
Author(s):  
Takahito Kawano ◽  
Yasuro Niidome ◽  
Takeshi Mori ◽  
Yoshiki Katayama ◽  
Takuro Niidome
Keyword(s):  
Gold Nanorods ◽  
Targeted Delivery ◽  
Near Infrared ◽  
Infrared Laser

Near-infrared laser light mediated cancer therapy by photothermal effect of Fe3O4 magnetic nanoparticles

Biomaterials ◽  
2013 ◽  
Vol 34 (16) ◽  
pp. 4078-4088 ◽  
Author(s):  
Maoquan Chu ◽  
Yuxiang Shao ◽  
Jinliang Peng ◽  
Xiangyun Dai ◽  
Haikuo Li ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Cancer Therapy ◽  
Near Infrared ◽  
Laser Light ◽  
Infrared Laser ◽  
Photothermal Effect ◽  
Fe3o4 Magnetic Nanoparticles

Photothermal cancer therapy by gold-ferrite nanocomposite and near-infrared laser in animal model

2015 ◽  
Vol 31 (2) ◽  
pp. 221-227 ◽  
Author(s):  
M. Heidari ◽  
N. Sattarahmady ◽  
N. Azarpira ◽  
H. Heli ◽  
A. R. Mehdizadeh ◽  
...  
Keyword(s):  
Animal Model ◽  
Cancer Therapy ◽  
Near Infrared ◽  
Infrared Laser

Treatment of tumor in lymph nodes using near-infrared laser light-activated thermosensitive liposome-encapsulated doxorubicin and gold nanorods

2017 ◽  
Vol 10 (12) ◽  
pp. 1676-1682 ◽  
Author(s):  
Daisuke Matsuki ◽  
Oladipo Adewale ◽  
Sachiko Horie ◽  
Junnosuke Okajima ◽  
Atsuki Komiya ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Gold Nanorods ◽  
Near Infrared ◽  
Laser Light ◽  
Infrared Laser ◽  
Thermosensitive Liposome

scholarly journals Near-Infrared Fluorescent Sorbitol Probe for Targeted Photothermal Cancer Therapy

Cancers ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 1286 ◽  
Author(s):  
Lee ◽  
Jung ◽  
Jo ◽  
Yang ◽  
Koh ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Laser Irradiation ◽  
Near Infrared ◽  
Photothermal Effect ◽  
Great Promise ◽  
Targeted Cancer Therapy ◽  
Potential Applications ◽  
Photothermal Property ◽  
Nir Laser

Abstract: Photothermal therapy (PTT) using a near-infrared (NIR) heptamethine cyanine fluorophore has emerged as an alternative strategy for targeted cancer therapy. NIR fluorophores showing a high molar extinction coefficient and low fluorescence quantum yield have considerable potential applications in photothermal cancer therapy. In this study, a bifunctional sorbitol–ZW800 conjugate was used as an advanced concept of photothermal therapeutic agents for in vivo cancer imaging and therapy owing to the high tumor targetability of the sorbitol moiety and excellent photothermal property of NIR heptamethine cyanine fluorophore. The sorbitol–ZW800 showed an excellent photothermal effect increased by 58.7 °C after NIR laser irradiation (1.1 W/cm2) for 5 min. The HT-29 tumors targeted by sorbitol–ZW800 showed a significant decrease in tumor volumes for 7 days after photothermal treatment. Therefore, combining the bifunctional sorbitol–ZW800 conjugate and NIR laser irradiation is an alternative way for targeted cancer therapy, and this approach holds great promise as a safe and highly efficient NIR photothermal agent for future clinical applications.

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