scholarly journals Bright Chromenylium Polymethine Dyes Enable Fast, Four-Color In Vivo Imaging with Shortwave Infrared Detection

2021 ◽  
Author(s):  
Emily D. Cosco ◽  
Bernardo A. Arús ◽  
Anthony L. Spearman ◽  
Timothy L. Atallah ◽  
Irene Lim ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Infrared Detection ◽  
Polymethine Dyes ◽  
Shortwave Infrared

scholarly journals Shortwave Infrared in Vivo Imaging with Gold Nanoclusters

Nano Letters ◽  
2017 ◽  
Vol 17 (10) ◽  
pp. 6330-6334 ◽  
Author(s):  
Yue Chen ◽  
Daniel M. Montana ◽  
He Wei ◽  
Jose M. Cordero ◽  
Marc Schneider ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Gold Nanoclusters ◽  
Shortwave Infrared

Real-time and long-time in vivo imaging in the shortwave infrared window of perforator vessels for more precise evaluation of flap perfusion

Biomaterials ◽  
2016 ◽  
Vol 103 ◽  
pp. 256-264 ◽  
Author(s):  
Shaoqing Feng ◽  
Jun Chen ◽  
Yan Wo ◽  
Yunxia Li ◽  
Shiyi Chen ◽  
...  
Keyword(s):  
Real Time ◽  
In Vivo Imaging ◽  
Precise Evaluation ◽  
Long Time ◽  
Perforator Vessels ◽  
Shortwave Infrared ◽  
Flap Perfusion ◽  
Infrared Window

scholarly journals Shortwave infrared polymethine fluorophores matched to excitation lasers enable non-invasive, multicolour in vivo imaging in real time

2020 ◽  
Vol 12 (12) ◽  
pp. 1123-1130
Author(s):  
Emily D. Cosco ◽  
Anthony L. Spearman ◽  
Shyam Ramakrishnan ◽  
Jakob G. P. Lingg ◽  
Mara Saccomano ◽  
...  
Keyword(s):  
Real Time ◽  
In Vivo Imaging ◽  
Non Invasive ◽  
Shortwave Infrared

Shortwave infrared fluorescence in vivo imaging of nerves for minimizing the risk of intraoperative nerve injury

Nanoscale ◽  
2019 ◽  
Vol 11 (42) ◽  
pp. 19736-19741 ◽  
Author(s):  
Heng Xu ◽  
Jun Chen ◽  
Zhujun Feng ◽  
Kan Fu ◽  
Yusen Qiao ◽  
...  
Keyword(s):  
Real Time ◽  
Nerve Injury ◽  
In Vivo Imaging ◽  
Peripheral Nerves ◽  
Imaging Agent ◽  
Nerve Injuries ◽  
Agent Based ◽  
Long Time ◽  
Shortwave Infrared

A novel nerve specific imaging agent based on SWIR QD-based in vivo imaging can markedly minimize the risk of iatrogenic nerve injuries during surgeries by providing real-time and long-time SWIR images of peripheral nerves in specific.

Fluorescent proteins for in vivo imaging, where's the biliverdin?

2020 ◽  
Vol 48 (6) ◽  
pp. 2657-2667
Author(s):  
Felipe Montecinos-Franjola ◽  
John Y. Lin ◽  
Erik A. Rodriguez
Keyword(s):  
Hydrogen Peroxide ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Fluorescent Protein ◽  
Fluorescent Proteins ◽  
Fluorescent Imaging ◽  
Infrared Light ◽  
Red Fluorescent Protein ◽  
Color Palette

Noninvasive fluorescent imaging requires far-red and near-infrared fluorescent proteins for deeper imaging. Near-infrared light penetrates biological tissue with blood vessels due to low absorbance, scattering, and reflection of light and has a greater signal-to-noise due to less autofluorescence. Far-red and near-infrared fluorescent proteins absorb light >600 nm to expand the color palette for imaging multiple biosensors and noninvasive in vivo imaging. The ideal fluorescent proteins are bright, photobleach minimally, express well in the desired cells, do not oligomerize, and generate or incorporate exogenous fluorophores efficiently. Coral-derived red fluorescent proteins require oxygen for fluorophore formation and release two hydrogen peroxide molecules. New fluorescent proteins based on phytochrome and phycobiliproteins use biliverdin IXα as fluorophores, do not require oxygen for maturation to image anaerobic organisms and tumor core, and do not generate hydrogen peroxide. The small Ultra-Red Fluorescent Protein (smURFP) was evolved from a cyanobacterial phycobiliprotein to covalently attach biliverdin as an exogenous fluorophore. The small Ultra-Red Fluorescent Protein is biophysically as bright as the enhanced green fluorescent protein, is exceptionally photostable, used for biosensor development, and visible in living mice. Novel applications of smURFP include in vitro protein diagnostics with attomolar (10−18 M) sensitivity, encapsulation in viral particles, and fluorescent protein nanoparticles. However, the availability of biliverdin limits the fluorescence of biliverdin-attaching fluorescent proteins; hence, extra biliverdin is needed to enhance brightness. New methods for improved biliverdin bioavailability are necessary to develop improved bright far-red and near-infrared fluorescent proteins for noninvasive imaging in vivo.

In vivo imaging of beta-amyloid load in transgenic rodents with [F-18]FDDNP microPET

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S588-S588
Author(s):  
Vladimir Kepe ◽  
Gregory M Cole ◽  
Jie Liu ◽  
Dorothy G Flood ◽  
Stephen P Trusko ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Beta Amyloid ◽  
Amyloid Load

In vivo imaging of liver injury and regeneration by functional two-photon microscopy

2016 ◽  
Vol 54 (12) ◽  
pp. 1343-1404
Author(s):  
A Ghallab ◽  
R Reif ◽  
R Hassan ◽  
AS Seddek ◽  
JG Hengstler
Keyword(s):  
Liver Injury ◽  
In Vivo Imaging ◽  
Two Photon Microscopy ◽  
Two Photon

In vivo imaging of human monocyte localization in the early and late inflammatory phase of mouse myocardial infarction

2020 ◽  
Author(s):  
J Iking ◽  
S Hermann ◽  
L Honold ◽  
M Kuhlmann ◽  
M Schäfers ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
In Vivo Imaging ◽  
Human Monocyte ◽  
Inflammatory Phase

In vivo imaging reveals prostate pathology in the PTEN knockout murine model of prostate cancer

2016 ◽  
Author(s):  
Alysha Bhatti ◽  
Almeida Gilberto Serrano de ◽  
Serena Tommasini Ghelfi ◽  
Alwyn Dart ◽  
Anabel Varela-Carver ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Murine Model ◽  
In Vivo Imaging

In vivo imaging of endocrine cell networks

2019 ◽  
Author(s):  
Patrice Mollard
Keyword(s):  
Endocrine Cell ◽  
In Vivo Imaging ◽  
Cell Networks
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