Structural correlation between some amides and a taste receptor model

1989 ◽  
Vol 37 (3) ◽  
pp. 737-740 ◽  
Author(s):  
Masahiro Tamura ◽  
Ichizo Shinoda ◽  
Hideo Okai ◽  
Charles H. Stammer
2011 ◽  
Vol 128 (1) ◽  
pp. 134-144 ◽  
Author(s):  
Zhong-Xiu Chen ◽  
Wen Wu ◽  
Wei-Bin Zhang ◽  
Shao-Ping Deng

2019 ◽  
Vol 118 (1) ◽  
pp. 8-13
Author(s):  
Boo-Gil Seok ◽  
Hyun-Suk Park

Background/Objectives: The purpose of this study is to find out the structural relationships among customer delight, exercise commitment, and psychological happiness to contribute developing exercise Apps. Methods/Statistical analysis: A questionnaire survey was conducted and 160 college students who are familiar with mobile exercise applications participated. The data analyzed with frequency analysis, exploratory factor analysis, confirmatory factor analysis, correlation analysis, and structural correlation analysis. The validity and the reliability were obtained: customer delight (χ2=26.532, df=14, CFI=.985, TLI=.971, RMSEA=.075), exercise commitment (χ2=113.802, df=49, CFI=.956, TLI=.941, RMSEA=.091), and psychological happiness (χ2=15.338, df=8, CFI=.989, TLI=.980, RMSEA=.076, and Cronbach’s α=.906~.938).


2019 ◽  
Vol 484 (1) ◽  
pp. 117-120
Author(s):  
V. O. Murovets ◽  
E. A. Sozontov ◽  
T. G. Zachepilo

Protein T1R3, the main subunit of sweet, as well as amino acid, taste receptor, is expressed in the epithelium of the tongue and gastro intestinal tract, in β–cells of the pancreas, hypothalamus, and numerous other organs. Recently, convincing witnesses of T1R3 involvement in control of carbohydrate and lipid metabolism, and control of production of incretines and insulin, have been determined. In the study on Tas1r3-gene knockout mouse strain and parent strain C57Bl/6J as control, priority data concerning the effect of T1R3 on the morphological characteristics of Langerhans islets in the pancreas, are obtained. In Tas1r3 knockout animals, it is found that the size of the islets and their density in pancreatic tissue are reduced, as compared to the parent strain. Additionally, a decrease of expression of active caspase-3 in islets of gene-knockouts is demonstrated. The obtained data show that the lack of a functional, gene encoding sweet-taste receptor protein causes a dystrophy of the islet tissue and associates to the development of pathological changes in the pancreas specific to type-2 diabetes and obesity in humans.


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