scholarly journals Investigations of the Low-Frequency Spectral Density of Cytochrome c upon Equilibrium Unfolding

2013 ◽  
Vol 117 (33) ◽  
pp. 9615-9625 ◽  
Author(s):  
Yuhan Sun ◽  
Venugopal Karunakaran ◽  
Paul M. Champion
2014 ◽  
Vol 111 (18) ◽  
pp. 6570-6575 ◽  
Author(s):  
Y. Sun ◽  
A. Benabbas ◽  
W. Zeng ◽  
J. G. Kleingardner ◽  
K. L. Bren ◽  
...  

2020 ◽  
Vol 20 (5) ◽  
pp. 1909-1921
Author(s):  
Seyed Nasrollah Mousavi ◽  
Davood Farsadizadeh ◽  
Farzin Salmasi ◽  
Ali Hosseinzadeh Dalir ◽  
Daniele Bocchiola

Abstract Knowledge of extreme pressures and fluctuations within stilling basins is of the utmost importance, as they may cause potential severe damages. It is complicated to measure the fluctuating pressures of hydraulic jumps in real-scale structures. Therefore, little information is available about the pressure fluctuations in the literature. In this paper, minimal and maximal pressures were analyzed on the flat bed of a stilling basin downstream of an Ogee spillway. Attention has been focused on dimensionless pressures related to the low and high cumulative probabilities of occurrence (P*0.1% and P*99.9%), respectively. The results were presented based on the laboratory-scale experiments. These parameters for the relatively high Froude numbers have not been investigated. The total standard uncertainty for the dimensionless mean pressures (P*m) was obtained around 1.87%. Spectral density analysis showed that the dominant frequency in the classical hydraulic jumps was about 4 HZ. Low-frequency of pressure fluctuations indicated the existence of large-scale vortices. In the zone near the spillway toe, P*0.1% reached negative values of around −0.3. The maximum values of pressure coefficients, namely |CP0.1%|max and CP99.9%max, were achieved around 0.19 and 0.24, respectively. New original expressions were proposed for P*0.1% and P*99.9%, which are useful for estimating extreme pressures.


1986 ◽  
Vol 61 (3) ◽  
pp. 1012-1017 ◽  
Author(s):  
A. R. Bazzy ◽  
J. B. Korten ◽  
G. G. Haddad

We studied the relationship between changing elbow joint angle and the power spectral density of the biceps brachii muscle electromyogram (EMG) during submaximal isometric contractions. For this purpose, we recorded the EMG of the biceps brachii muscle with surface electrodes in 13 subjects. Each subject held a 2.8-kg weight and contracted the biceps isometrically for 30 s at one of two lengths. The length of the muscle was changed by flexing the forearm toward the upper arm to form an angle of 135 degrees (L1) or 45 degrees (L2). We found that the mean centroid frequency (fc) of the EMG power spectral density was 26% lower at L1 than at L2 (P less than 0.01). For each subject there was no significant change in fc during the isometric contraction at either angle. In addition, in nine subjects who sustained fatiguing contractions of the biceps with a 6-kg load, fc decreased by 15% (P less than 0.025). These data suggest that a change in the length at which a muscle contracts isometrically can alter or induce indirectly an alteration in the frequency content of its EMG. This finding may have important implications for the assessment of respiratory muscle EMG especially during loaded breathing.


2011 ◽  
Vol 54 (2) ◽  
pp. 116-128 ◽  
Author(s):  
Mark Paulus

This paper presents a set of experimental data comparing repetitive shock (RS) vibration, single-axis electrodynamic (ED) vibration, and multi-axis ED vibration. It was found that multi-axis testing is more severe than single-axis testing at the same level. In addition, weaknesses were found in the RS system at low frequency. Smoothing of the data or poor line resolution was also shown to change the overall severity of a test. A poor correlation was shown between the power spectral density (PSD) and the rate of natural frequency change (RFC) over a wide frequency shift. The change in natural frequency caused the initial PSD to be an ineffective indicator of test severity. Quantification of the severity of the test profile can be accomplished through characterization of the RFC.


2008 ◽  
Vol 17 (6) ◽  
pp. 575-583 ◽  
Author(s):  
Shih-Fong Huang ◽  
Po-Yi Tsai ◽  
Wen-Hsu Sung ◽  
Chih-Yung Lin ◽  
Tien-Yow Chuang

Sympathovagal modulation during immersion in a virtual environment is an important influence on human performance of a task. The aim of this study is to investigate sympathovagal modulation using heart rate variability and perceived exertion during exercise in a virtual reality (VR) environment. Sixteen young healthy volunteers were tested while using a stationary bicycle and maintained at an anaerobic threshold intensity for exercise sessions of approximately 10 min duration. Four randomized viewing alternatives were provided including desktop monitor, projector, head mounted device (HMD), and no simulation display. The “no simulation display” served as the control group. A quick ramp exercise test was conducted and maintained at an anaerobic threshold intensity for each session to evaluate power spectral density and rating of perceived exertion (RPE). The sampled heart rate data were rearranged by cubic spline interpolation into power spectrums spanning the ultra-low frequency (ULF) to high frequency (HF) range. A significant difference was found between the no-display and projector groups for total power (TP) and very low frequency (VLF) components. In particular, there was a significant difference when comparing HMD and no-display exercise RPE curves within 6 min of cycling and at the termination of the exercise. A significant difference was also achieved in projector vs. control group comparison at the termination of the exercise. Our results indicate that the use of HMD and the projected VR during cycling can reduce the TP and VLF power spectral density through a proposed decrease in the renin-angiotensin system, with the implication that this humoral effect may enable anaerobic exercise for longer durations through a reduction in sympathetic tone and subsequent increased blood flow to the muscles.


2017 ◽  
Vol 28 (02) ◽  
pp. 1750019 ◽  
Author(s):  
A. T. da Cunha Lima ◽  
I. C. da Cunha Lima ◽  
M. P. de Almeida

We calculate the power spectral density and velocity correlations for a turbulent flow of a fluid inside a duct. Turbulence is induced by obstructions placed near the entrance of the flow. The power spectral density is obtained for several points at cross-sections along the duct axis, and an analysis is made on the way the spectra changes according to the distance to the obstruction. We show that the differences on the power spectral density are important in the lower frequency range, while in the higher frequency range, the spectra are very similar to each other. Our results suggest the use of the changes on the low frequency power spectral density to identify the occurrence of obstructions in pipelines. Our results show some frequency regions where the power spectral density behaves according to the Kolmogorov hypothesis. At the same time, the calculation of the power spectral densities at increasing distances from the obstructions indicates an energy cascade where the spectra evolves in frequency space by spreading the frequency amplitude.


Author(s):  
Владимир Васильевич Измайлов ◽  
Марина Вячеславовна Новоселова

Исследована нанотопография некоторых типичных технических поверхностей и экспериментально определены характеристики профиля наношероховатости как случайного процесса - автокорреляционная функция и спектральная плотность. Показано, что для исследованных поверхностей их профилограммы могут рассматриваться как реализации случайного стационарного нормального эргодического процесса. Проведена визуальная проверка нормальности процесса сравнением экспериментальных значений ординат профиля с теоретическими значениями, подчиняющимися нормальному распределению, а также сравнением полигона частот с теоретической функцией плотности вероятности нормального распределения. Количественное подтверждение нормальности процесса выполнено с применением критерия согласия Колмогорова. Показано, что на уровне значимости p = 0,05 гипотеза о нормальности случайного процесса (профиля наношероховатости поверхности) не противоречит экспериментальным результатам. Определены интервалы корреляции рассмотренных процессов. Вид автокорреляционных функций и величины интервалов корреляции говорят о случайном характере профиля поверхности: на интервале, равном одному - двум средним значениям шага неровностей профиля его ординаты становятся практически некоррелированными. Графики спектральных плотностей свидетельствуют о том, что профиль поверхности можно рассматривать как широкополосный случайный шум с преобладанием низкочастотных составляющих. The nanotopography of some typical technical surfaces is investigated and the characteristics of the nanoroughness profile as a random process are experimentally determined - the autocorrelation function and spectral density. It is shown that for the investigated surfaces, their profilograms can be considered as realizations of a random stationary normal ergodic process. A visual check of the process normality was carried out by comparing the experimental values of the profile ordinates with theoretical values obeying the normal distribution, as well as by comparing the frequency polygon with the theoretical probability density function of the normal distribution. Quantitative confirmation of the process normality was carried out using the Kolmogorov goodness-of-fit test. It is shown that at the significance level p = 0,05, the hypothesis about the normality of a random process (surface nanoroughness profile) does not contradict the experimental results. The correlation intervals of the considered processes are determined. The form of the autocorrelation functions and the values of the correlation intervals indicate the random nature of the surface profile: in the interval equal to one or two average values of the step of the irregularities of the profile, its ordinates become practically uncorrelated. Spectral density plots indicate that the surface profile can be considered as a wide-band random noise with a predominance of low-frequency components.


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