scholarly journals Competitive Adsorption of Thiolated Polyethylene Glycol and Mercaptopropionic Acid on Gold Nanoparticles Measured by Physical Characterization Methods

Langmuir ◽  
2010 ◽  
Vol 26 (12) ◽  
pp. 10325-10333 ◽  
Author(s):  
De-Hao Tsai ◽  
Frank W. DelRio ◽  
Robert I. MacCuspie ◽  
Tae Joon Cho ◽  
Michael R. Zachariah ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Polyethylene Glycol ◽  
Competitive Adsorption ◽  
Physical Characterization ◽  
Characterization Methods ◽  
Mercaptopropionic Acid ◽  
Thiolated Polyethylene Glycol

Photochemical transformations of thiolated polyethylene glycol coatings on gold nanoparticles

2016 ◽  
Vol 3 (5) ◽  
pp. 1090-1102 ◽  
Author(s):  
Stacey M. Louie ◽  
Justin M. Gorham ◽  
Eric A. McGivney ◽  
Jingyu Liu ◽  
Kelvin B. Gregory ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Polyethylene Glycol ◽  
Gold Nanoparticle ◽  
Uv Irradiation ◽  
Colloidal Stability ◽  
Chain Scission ◽  
Photochemical Reactions ◽  
Surface Coatings ◽  
Photochemical Transformations ◽  
Thiolated Polyethylene Glycol

Photochemical reactions can cause significant transformations of manufactured nanomaterials and their surface coatings in sunlit environments. In this study, loss of thiolated polyethylene glycol from gold nanoparticle surfaces by chain scission was observed under UV irradiation and resulted in diminished colloidal stability.

Seed-mediated synthesis and PEG coating of gold nanoparticles for controlling morphology and sizes

MRS Advances ◽  
2020 ◽  
Vol 5 (63) ◽  
pp. 3353-3360
Author(s):  
Susana Helena Arellano Ramírez ◽  
Perla García Casillas ◽  
Christian Chapa González
Keyword(s):  
Gold Nanoparticles ◽  
Polyethylene Glycol ◽  
Room Temperature ◽  
Colloidal Stability ◽  
Infrared Spectrometry ◽  
Ammonium Bromide ◽  
Chloroauric Acid ◽  
Vis Spectroscopy ◽  
Seed Mediated ◽  
Peg Coating

AbstractA significant area of research is biomedical applications of nanoparticles which involves efforts to control the physicochemical properties through simple and scalable processes. Gold nanoparticles have received considerable attention due to their unique properties that they exhibit based on their morphology. Gold nanospheres (AuNSs) and nanorods (AuNRs) were prepared with a seed-mediated method followed of polyethylene glycol (PEG)-coating. The seeds were prepared with 0.1 M cetyltrimethyl-ammonium bromide (CTAB), 0.005 M chloroauric acid (HAuCl4), and 0.01 M sodium borohydride (NaBH4) solution. Gold nanoparticles with spherical morphology was achieved by growth by aggregation at room temperature, while to achieve the rod morphology 0.1 M silver nitrate (AgNO3) and 0.1 M ascorbic acid solution were added. The gold nanoparticles obtained by the seed-mediated synthesis have spherical or rod shapes, depending on the experimental conditions, and a uniform particle size. Surface functionalization was developed using polyethylene glycol. Morphology, and size distribution of AuNPs were evaluated by Field Emission Scanning Electron Microscopy. The average size of AuNSs, and AuNRs was 7.85nm and 7.96 x 31.47nm respectively. Fourier transform infrared spectrometry was performed to corroborate the presence of PEG in the AuNPs surface. Additionally, suspensions of AuNSs and AuNRs were evaluated by UV-Vis spectroscopy. Gold nanoparticles were stored for several days at room temperature and it was observed that the colloidal stability increased once gold nanoparticles were coated with PEG due to the shield formed in the surface of the NPs and the increase in size which were 9.65±1.90 nm of diameter for AuNSs and for AuNRs were 29.03±5.88 and 8.39±1.02 nm for length and transverse axis, respectively.

Ultrasmall Gold Nanoparticles Behavior in Vivo Modulated by Surface Polyethylene Glycol (PEG) Grafting

2016 ◽  
Vol 28 (1) ◽  
pp. 239-243 ◽  
Author(s):  
Shuaidong Huo ◽  
Shizhu Chen ◽  
Ningqiang Gong ◽  
Juan Liu ◽  
Xianlei Li ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Polyethylene Glycol

Synthesis of Gold Nanoparticles in Liquid Polyethylene Glycol by Sputter Deposition and Temperature Effects on their Size and Shape

2011 ◽  
Vol 115 (8) ◽  
pp. 3279-3285 ◽  
Author(s):  
Yoshikiyo Hatakeyama ◽  
Takeshi Morita ◽  
Satoshi Takahashi ◽  
Kei Onishi ◽  
Keiko Nishikawa
Keyword(s):  
Gold Nanoparticles ◽  
Polyethylene Glycol ◽  
Temperature Effects ◽  
Sputter Deposition ◽  
Size And Shape

scholarly journals SYNTHESIS AND STABILITY OF RESVERATROL-CONJUGATED GOLD NANOPARTICLES MODIFIED WITH POLYETHYLENE GLYCOL

2020 ◽  
pp. 230-236
Author(s):  
RADITYA ISWANDANA ◽  
RICHA NURSELVIANA ◽  
SUTRIYO SUTRIYO
Keyword(s):  
Particle Size ◽  
Gold Nanoparticles ◽  
Polyethylene Glycol ◽  
Zeta Potential ◽  
High Performance ◽  
Entrapment Efficiency ◽  
Test Results ◽  
Novel Method ◽  
The Stability ◽  
Phosphate Buffered Saline

Objective: Gold nanoparticles (AuNPs) are highly useful for drug delivery, but their application is limited by their stability as they readily aggregate.This issue can be prevented by adding a stabilizing agent such as resveratrol (RSV), which is a polyphenol derived from plants, that is used to preventcancer. Therefore, we propose a novel method to prepare stable RSV-conjugated nanoparticles modified with polyethylene glycol (RSV-AuNP-PEG).Methods: In the first step, the Turkevich method was used to synthesize the AuNPs. Then, PEG was added as stabilizer agent and conjugated with RSV.The synthesized conjugates were characterized using ultraviolet-visible spectrophotometry, Fourier transform infrared spectroscopy, particle sizeanalysis, and high-performance liquid chromatography.Results: The obtained RSV-AuNP-PEG had a particle size of 83.93 nm with a polydispersity index (PDI) of 0.562 and formed a translucent purple-redfluid in solution. The zeta potential was −22.9 mV, and the highest entrapment efficiency was 75.86±0.66%. For comparison, the RSV-AuNP solutionwas purple and turbid, the particle size was 51.97 nm with a PDI of 0.694, and the zeta potential was −24.6 mV. The stability test results showed thatthe storage stability of RSV-AuNP-PEG was better than that of AuNP-RSV. Further, the RSV-AuNP-PEG was shown to be most stable in 2% bovine serumalbumin (BSA) while the AuNP-RSV was most stable in 2% BSA in phosphate-buffered saline pH 7.4.Conclusion: These results show that modification of RSV-conjugated AuNPs with PEG effectively prevents their aggregation in storage, but only incertain mediums.

scholarly journals Basic Physicochemical Properties of Polyethylene Glycol Coated Gold Nanoparticles that Determine Their Interaction with Cells

2016 ◽  
Vol 55 (18) ◽  
pp. 5483-5487 ◽  
Author(s):  
Pablo del Pino ◽  
Fang Yang ◽  
Beatriz Pelaz ◽  
Qian Zhang ◽  
Karsten Kantner ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Polyethylene Glycol ◽  
Physicochemical Properties

Electrooxidation of Methanol on Carbon Supported Gold Nanoparticles

2013 ◽  
Vol 313-314 ◽  
pp. 232-236
Author(s):  
Dan Zhang
Keyword(s):  
Gold Nanoparticles ◽  
Catalytic Activity ◽  
Competitive Adsorption ◽  
Chemical Reduction ◽  
Reduction Process ◽  
Carbon Support ◽  
Transmission Electron ◽  
Supported Gold Nanoparticles ◽  
Supported Gold

Activated carbon supported gold nanoparticles (Au/C) were prepared by a chemical reduction process using NaBH4as a reducing agent. The characterization of transmission electron microscope indicated that the Au nanoparticles (AuNPs) in the Au/C catalyst were highly well dispersed on the carbon support. The catalytic activity of the Au/C catalyst for the methanol electrooxidation (MEO) was investigated by the cyclic voltammetry (CV). The results displayed that the Au/C catalyst exhibited a favorable catalytic activity towards the MEO in alkaline solution. Moreover, the competitive adsorption between OH-and CH3OH on the surface of the AuNPs in the Au/C catalyst existed in the course of the MEO. Based on this competitive adsorption, the mechanism of the MEO on the Au/C catalyst was further investigated.

A facile method to in situ fabricate three dimensional gold nanoparticle micropatterns in a cell-resistant hydrogel

2016 ◽  
Vol 15 (2) ◽  
pp. 181-186
Author(s):  
Ming-Hao Yao ◽  
Jie Yang ◽  
Dong-Hui Zhao ◽  
Rui-Xue Xia ◽  
Rui-Mei Jin ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Polyethylene Glycol ◽  
Gold Nanoparticle ◽  
Three Dimensional ◽  
Photochemical Synthesis ◽  
A Cell

A facile method for in situ fabrication of three-dimensional gold nanoparticles micropatterns throughout a polyethylene glycol hydrogel substrate has been developed by combining photochemical synthesis of gold nanoparticles with photolithography technology.

scholarly journals Factors Influencing the Surface Functionalization of Citrate Stabilized Gold Nanoparticles with Cysteamine, 3-Mercaptopropionic Acid or l-Selenocystine for Sensor Applications

Chemosensors ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. 80
Author(s):  
Georgia I. Sakellari ◽  
Nicole Hondow ◽  
Philip H.E. Gardiner
Keyword(s):  
Gold Nanoparticles ◽  
Co Adsorption ◽  
Limiting Factor ◽  
Experimental Conditions ◽  
Mercaptopropionic Acid ◽  
X Ray ◽  
Sensor Applications ◽  
Factors Influencing ◽  
Electrostatic Repulsions ◽  
Functionalized Aunps

Thiols and selenides bind to the surface of gold nanoparticles (AuNPs) and thus provide suitable platforms for the fabrication of sensors. However, the co-existence of adsorbed citrate on the surface of the nanoparticles can influence their functionalization behavior and potentially their sensing performance measured by the extent of particle aggregation. In this study, the functionalization of purchased (7.3 ± 1.2 nm) and in-house prepared AuNPs (13.8 ± 1.2 nm), under the same experimental conditions with either cysteamine (Cys), 3-mercaptopropionic acid (3-MPA), or l-selenocystine (SeCyst) was investigated. 1H-NMR measurements showed distinct citrate signatures on the in-house synthesized citrate-stabilized AuNPs, while no citrate signals were detected on the purchased AuNPs other than evidence of the presence of α-ketoglutaric acid. Carboxylate-containing species attributed to either citrate or α-ketoglutaric acid were identified in all functionalized AuNPs. ATR-FTIR spectroscopy confirmed the functionalization of AuNPs with Cys and 3-MPA, and energy dispersive X-ray (EDX) spectroscopy measurements suggested the formation of SeCyst functionalized AuNPs. Co-adsorption rather than displacement by the functionalizing agents and carboxylate-containing molecules was indicated, which for Cys and SeCyst functionalized AuNPs was also the aggregation limiting factor. In contrast, the behavior of 3-MPA functionalized AuNPs could be attributed to electrostatic repulsions between the functionalized groups.

Sign in / Sign up

Export Citation Format

Share Document