Sativanine-E, a New 13-Membered Cyclopeptide Alkaloid Containing a Short Side-Chain, from Zizyphus sativa

1985 ◽  
Vol 48 (4) ◽  
pp. 555-558 ◽  
Author(s):  
A. H. Shah ◽  
V. B. Pandey ◽  
G. Eckhardt ◽  
R. Tschesche
2020 ◽  
Vol 22 (1) ◽  
pp. 155
Author(s):  
Mikhail V. Diachkov ◽  
Karoll Ferrer ◽  
Jana Oklestkova ◽  
Lucie Rarova ◽  
Vaclav Bazgier ◽  
...  

Brassinosteroids are a class of plant hormones that regulate a broad range of physiological processes such as plant growth, development and immunity, including the suppression of biotic and abiotic stresses. In this paper, we report the synthesis of new brassinosteroid analogues with a nitrogen-containing side chain and their biological activity on Arabidopis thaliana. Based on molecular docking experiments, two groups of brassinosteroid analogues were prepared with short and long side chains in order to study the impact of side chain length on plants. The derivatives with a short side chain were prepared with amide, amine and ammonium functional groups. The derivatives with a long side chain were synthesized using amide and ammonium functional groups. A total of 25 new brassinosteroid analogues were prepared. All 25 compounds were tested in an Arabidopsis root sensitivity bioassay and cytotoxicity screening. The synthesized substances showed no significant inhibitory activity compared to natural 24-epibrassinolide. In contrast, in low concentration, several compounds (8a, 8b, 8e, 16e, 22a and 22e) showed interesting growth-promoting activity. The cytotoxicity assay showed no toxicity of the prepared compounds on cancer and normal cell lines.


Author(s):  
Sahng Hyuck Woo ◽  
Aurélie Taguet ◽  
Belkacem Otazaghine ◽  
Alia Akrout ◽  
Sara Cavaliere ◽  
...  

1978 ◽  
Vol 9 (36) ◽  
Author(s):  
C. DELSETH ◽  
R. M. K. CARLSON ◽  
C. DJERASSI ◽  
T. R. ERDMAN ◽  
P. J. SCHEUER

Desalination ◽  
2006 ◽  
Vol 193 (1-3) ◽  
pp. 398-404 ◽  
Author(s):  
M.G. De Angelis ◽  
S. Lodge ◽  
M. Giacinti Baschetti ◽  
G.C. Sarti ◽  
F. Doghieri ◽  
...  

2015 ◽  
Vol 40 (42) ◽  
pp. 14430-14435 ◽  
Author(s):  
S. Siracusano ◽  
V. Baglio ◽  
E. Moukheiber ◽  
L. Merlo ◽  
A.S. Aricò

2017 ◽  
Vol 192 ◽  
pp. 477-489 ◽  
Author(s):  
Stefania Siracusano ◽  
Vincenzo Baglio ◽  
Nicholas Van Dijk ◽  
Luca Merlo ◽  
Antonino Salvatore Aricò

2019 ◽  
Vol 578 ◽  
pp. 136-148 ◽  
Author(s):  
Stefania Siracusano ◽  
Claudio Oldani ◽  
Maria Assunta Navarra ◽  
Stefano Tonella ◽  
Lucia Mazzapioda ◽  
...  

1995 ◽  
Vol 32 (7) ◽  
pp. 1017-1034 ◽  
Author(s):  
J.R. Disnar ◽  
Y. Héroux

Carbonate rocks of the Ordovician Thumb Mountain Formation, host to the Zn–Pb Polaris deposit, contain hydrocarbons that show types of alteration classically attributed to biodegradation and water washing. The hydrocarbons of the upper part of this formation and of the overlying Irene Bay Formation indicate alterations due to water washing only. The hydrocarbons of the impermeable shales of the overlying Cape Phillips Formation display indices of only higher thermal maturity than the underlying units. Contrary to classical concepts of hydrocarbon biodegradation, n-alkanes, cyclohexylalkanes, even isoprenoids and perhaps also steranes seem to have been degraded simultaneously and not successively in this sequence. This alteration process is mainly responsible for a log-linear decrease of the amounts of n-alkanes and cyclohexylalkanes with increasing depth. The severe and uniform alteration of aromatic hydrocarbons throughout the interval, which is opposite to the progressive alteration of associated n-alkanes, can be attributed solely to water washing. This conclusion necessitates a reconsideration of previous interpretations attributing the loss of short-side chain substituted polyaromatic compounds to microbial activity. Hopanes, tri-and tetra–cyclic terpanes as well as aromatic steroids and hopanoids seem to have been unaffected by the alteration phenomena. The increase in the degree of alteration of the hydrocarbons with increasing depth implies that the responsible migrating fluid circulated per ascensum.


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