Comparative Proteomic Analysis of Paclitaxel Sensitive A2780 Epithelial Ovarian Cancer Cell Line and Its Resistant Counterpart A2780TC1 by 2D-DIGE: The Role of ERp57

2009 ◽  
Vol 8 (4) ◽  
pp. 1902-1912 ◽  
Author(s):  
Lucia Cicchillitti ◽  
Michela Di Michele ◽  
Andrea Urbani ◽  
Cristiano Ferlini ◽  
Maria Benedetta Donati ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Proteomic Analysis ◽  
Ovarian Cancer Cell ◽  
Ovarian Cancer Cell Line ◽  
Cancer Cell Line ◽  
Epithelial Ovarian Cancer Cell ◽  
2D Dige ◽  
Comparative Proteomic Analysis

scholarly journals 2336 Novel PGF2a synthesis pathway in epithelial ovarian cancer

2018 ◽  
Vol 2 (S1) ◽  
pp. 22-22
Author(s):  
Muhan Hu ◽  
Ekta Tiwary ◽  
Rebecca Arend ◽  
Michael Miller
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Ovarian Cancer Cell ◽  
Ovarian Cancer Cell Line ◽  
Cancer Cell Line ◽  
High Grade ◽  
Epithelial Ovarian Cancer Cell ◽  
Main Mode ◽  
Study Population

OBJECTIVES/SPECIFIC AIMS: To understand the role of PGF2a and to characterize a novel cyclooxyrgenase (COX)-independent prostaglandin synthesis pathway in epithelial ovarian cancer. METHODS/STUDY POPULATION: We used high grade epithelial ovarian cancer cell line (OVCAR3) as a model to study our pathway. Our main mode of PGF2a detection is through mass spectrometry. RESULTS/ANTICIPATED RESULTS: Our current results suggest the OVCAR3 cells may synthesize PGF2a independently of COX enzymes. We anticipate this novel pathway may be dependent on the TGFb pathway. DISCUSSION/SIGNIFICANCE OF IMPACT: Understanding the role and synthesis pathway of PGF2a may allow us to uncover a novel therapeutic pathway for high grade ovarian cancer.

scholarly journals Overexpressing the CCL2 chemokine in an epithelial ovarian cancer cell line results in latency of in vivo tumourigenicity

Oncogenesis ◽  
2012 ◽  
Vol 1 (9) ◽  
pp. e27-e27 ◽  
Author(s):  
P Wojnarowicz ◽  
K Gambaro ◽  
M de Ladurantaye ◽  
M C J Quinn ◽  
D Provencher ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Ovarian Cancer Cell ◽  
Ovarian Cancer Cell Line ◽  
Cancer Cell Line ◽  
Epithelial Ovarian Cancer Cell

Proteome profiling of human epithelial ovarian cancer cell line TOV-112D

2005 ◽  
Vol 275 (1-2) ◽  
pp. 25-55 ◽  
Author(s):  
Jean-Philippe Gagné ◽  
Pierre Gagné ◽  
Joanna M. Hunter ◽  
Marie-Ève Bonicalzi ◽  
Jean-François Lemay ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Ovarian Cancer Cell ◽  
Ovarian Cancer Cell Line ◽  
Cancer Cell Line ◽  
Epithelial Ovarian Cancer Cell ◽  
Proteome Profiling
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