1D GaAs Detector Arrays for Digital X-ray Imaging with a 108- m Spatial Resolution

Phase-contrast synchrotron-based X-ray imaging using an X-ray interferometer provides high sensitivity and high spatial resolution, and it has the ability to depict the fine morphological structures of biological soft tissues, including tumors. In this study, we quantitatively compared phase-contrast synchrotron-based X-ray computed tomography images and images of histopathological hematoxylin-eosin-stained sections of spontaneously occurring rat testicular tumors that contained different types of cells. The absolute densities measured on the phase-contrast synchrotron-based X-ray computed tomography images correlated well with the densities of the nuclear chromatin in the histological images, thereby demonstrating the ability of phase-contrast synchrotron-based X-ray imaging using an X-ray interferometer to reliably identify the characteristics of cancer cells within solid soft tissue tumors. In addition, 3-dimensional synchrotron-based phase-contrast X-ray computed tomography enables screening for different structures within tumors, such as solid, cystic, and fibrous tissues, and blood clots, from any direction and with a spatial resolution down to 26 μm. Thus, phase-contrast synchrotron-based X-ray imaging using an X-ray interferometer shows potential for being useful in preclinical cancer research by providing the ability to depict the characteristics of tumor cells and by offering 3-dimensional information capabilities.

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ZnWO4 Nanoparticle Scintillators for High Resolution X-ray Imaging

Nanomaterials ◽

10.3390/nano10091721 ◽

2020 ◽

Vol 10 (9) ◽

pp. 1721

Author(s):

Heon Yong Jeong ◽

Hyung San Lim ◽

Ju Hyuk Lee ◽

Jun Heo ◽

Hyun Nam Kim ◽

...

Keyword(s):

Particle Size ◽

Zinc Oxide ◽

High Resolution ◽

Tungsten Oxide ◽

Spatial Resolution ◽

High Spatial Resolution ◽

X Ray ◽

X Ray Imaging ◽

Average Size ◽

And Tungsten

The effect of scintillator particle size on high-resolution X-ray imaging was studied using zinc tungstate (ZnWO4) particles. The ZnWO4 particles were fabricated through a solid-state reaction between zinc oxide and tungsten oxide at various temperatures, producing particles with average sizes of 176.4 nm, 626.7 nm, and 2.127 μm; the zinc oxide and tungsten oxide were created using anodization. The spatial resolutions of high-resolution X-ray images, obtained from utilizing the fabricated particles, were determined: particles with the average size of 176.4 nm produced the highest spatial resolution. The results demonstrate that high spatial resolution can be obtained from ZnWO4 nanoparticle scintillators that minimize optical diffusion by having a particle size that is smaller than the emission wavelength.

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Investigation of the luminescence, crystallographic and spatial resolution properties of LSO:Tb scintillating layers used for X-ray imaging applications

Radiation Measurements ◽

10.1016/j.radmeas.2013.12.005 ◽

2014 ◽

Vol 62 ◽

pp. 28-34 ◽

Cited By ~ 10

Author(s):

A. Cecilia ◽

V. Jary ◽

M. Nikl ◽

E. Mihokova ◽

D. Hänschke ◽

...

Keyword(s):

Spatial Resolution ◽

X Ray ◽

X Ray Imaging

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1D GaAs Detector Arrays for Digital X-ray Imaging

Russian Microelectronics ◽

10.1023/b:rumi.0000046967.33265.a4 ◽

2004 ◽

Vol 33 (6) ◽

pp. 373-376

Author(s):

V. F. Dvoryankin ◽

Yu. M. Dikaev ◽

A. I. Krikunov ◽

A. A. Kudryashov ◽

A. A. Telegin ◽

...

Keyword(s):

Detector Arrays ◽

X Ray ◽

X Ray Imaging

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APD-based x-ray imaging telescope using Fresnel zone plates for extremely high spatial resolution

10.1117/12.618452 ◽

2005 ◽

Cited By ~ 1

Author(s):

Michael R. Squillante ◽

Richard A. Myers ◽

Mitchell Woodring ◽

James F. Christian ◽

Frank Robertson ◽

...

Keyword(s):

Spatial Resolution ◽

High Spatial Resolution ◽

Fresnel Zone ◽

Fresnel Zone Plates ◽

X Ray ◽

Zone Plates ◽

X Ray Imaging ◽

Imaging Telescope

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High-sensitivity high-resolution X-ray imaging with soft-sintered metal halide perovskites

Nature Electronics ◽

10.1038/s41928-021-00644-3 ◽

2021 ◽

Vol 4 (9) ◽

pp. 681-688

Author(s):

Sarah Deumel ◽

Albert van Breemen ◽

Gerwin Gelinck ◽

Bart Peeters ◽

Joris Maas ◽

...

Keyword(s):

High Sensitivity ◽

Metal Halide ◽

Detector Arrays ◽

X Ray ◽

Carrier Lifetimes ◽

Sintered Metal ◽

X Ray Imaging ◽

Imaging Detector ◽

High Carrier ◽

Halide Perovskites

AbstractTo realize the potential of artificial intelligence in medical imaging, improvements in imaging capabilities are required, as well as advances in computing power and algorithms. Hybrid inorganic–organic metal halide perovskites, such as methylammonium lead triiodide (MAPbI3), offer strong X-ray absorption, high carrier mobilities (µ) and long carrier lifetimes (τ), and they are promising materials for use in X-ray imaging. However, their incorporation into pixelated sensing arrays remains challenging. Here we show that X-ray flat-panel detector arrays based on microcrystalline MAPbI3 can be created using a two-step manufacturing process. Our approach is based on the mechanical soft sintering of a freestanding absorber layer and the subsequent integration of this layer on a pixelated backplane. Freestanding microcrystalline MAPbI3 wafers exhibit a sensitivity of 9,300 µC Gyair–1 cm–2 with a μτ product of 4 × 10–4 cm2 V–1, and the resulting X-ray imaging detector, which has 508 pixels per inch, combines a high spatial resolution of 6 line pairs per millimetre with a low detection limit of 0.22 nGyair per frame.

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A Simulation of a Novel High Quantum Efficiency Scintillating Fiber Detector with Anti-scatter Properties for Megavoltage X-Ray Imaging

10.32920/ryerson.14653425.v1 ◽

2021 ◽

Author(s):

James Day

Keyword(s):

Spatial Resolution ◽

Detection Efficiency ◽

Original Design ◽

High Quantum Efficiency ◽

Imaging Device ◽

X Ray ◽

Image Guided Radiation Therapy ◽

X Ray Imaging ◽

High Detection Efficiency ◽

Square Array

To further develop a MV x-ray portal imaging device with high detection efficiency and adequate spatial resolution for image guided radiation therapy, the experimental results for a prototype detector were matched using Monte-Carlo software to then improve upon the design. The simulation and experiment were carried out using a 6 MV beam from a linear accelerator machine. An adequate match was obtained with the spatial resolution matching up to a MTF value of 0.2 and then diverging and the total signal registered in the central fiber was matched for field sizes ranging from 3 cm by 3 cm to 20 cm by 20 cm for 5 cm, 15 cm and 25 cm air gaps within 3%. The design was altered from a hexagonal array of round double cladded fibers to a square array of single cladded square fibers. The spatial resolution was improved from 0.242 lp mm-1 to 0.359 lp mm-1 at an MTF value of 0.5 from the original design to a square array of square fibers 0.5 mm wide separated by 0.25 mm of lead foil. With further optimization of the detector design it may be possible to increase spatial resolution for MV x-ray imaging while maintaining an adequate detection efficiency.

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Application of the Gatan X-ray Ultramicroscope (XuM) to the Investigation of Material and Biological Samples

Microscopy Today ◽

10.1017/s1551929500062313 ◽

2008 ◽

Vol 16 (6) ◽

pp. 14-17 ◽

Cited By ~ 5

Author(s):

Paul Mainwaring

Keyword(s):

Sample Size ◽

Spatial Resolution ◽

Biological Samples ◽

Easy Access ◽

X Ray ◽

Analytical Functions ◽

Important Development ◽

X Ray Imaging ◽

Sem Imaging ◽

Power Capability

X-ray ultramicroscopy in the SEM is a relatively new application in the wider field of X-ray microscopy. This latter field includes synchrotron and cabinet-based systems that vary in their X-ray power, capability, sample size, spatial resolution, and convenience. One important capability of the SEM-hosted X-ray microscope is that the normal SEM imaging and analytical functions such as secondary and backscattered imaging and microanalysis by EDX or WDS are unimpeded. X-ray imaging then serves as a complement to the normal use of the SEM. The convenience of easy access in an SEM lab to an X-ray microscope with 3D tomographic capability makes this an important development.

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