Interaktionseffekte Monoamin-relevanter genetischer Polymorphismen mit Traits des TPQ

2000 ◽  
Vol 21 (3) ◽  
pp. 191-199 ◽  
Author(s):  
Alexander Strobel ◽  
Burkhard Brocke ◽  
Richard P. Ebstein
Keyword(s):  
Serotonin Transporter ◽  
Harm Avoidance ◽  
Personality Questionnaire ◽  
Novelty Seeking

Zusammenfassung: Fortschritte in der Molekulargenetik ermöglichen es, den Erklärungsbeitrag genetischer Polymorphismen mit funktioneller Relevanz zum genetischen Hintergrund der Erblichkeitskomponente einiger Persönlichkeitstraits zu untersuchen. Bisherige Befunde sprechen für potentielle Assoziationen eines Polymorphismus im Dopamin-D4-Rezeptor-Gen (DRD4 Exon 3) mit der Dimension Novelty Seeking (NS) des Tridimensional Personality Questionnaire (TPQ) sowie eines Polymorphismus des Serotonin-Transporter-Gens (5-HTTLPR) mit TPQ Harm Avoidance (HA). Die Betrachtung von Interaktionen dieser Polymorphismen kann einen Beitrag zur Klärung von Inkonsistenzen in bisherigen Assoziationsstudien leisten. In der vorliegenden Arbeit wurden für 134 Personen Interaktionen von DRD4 Exon 3 und 5-HTTLPR sowie einem Polymorphismus des Gens für COMT auf die Faktorwerte der TPQ-Subskalen überprüft. Es zeigten sich Tendenzen zu Interaktionen zwischen DRD4 Exon 3 und 5-HTTLPR bei dem HA-Faktor sowie zwischen DRD4 Exon 3 und dem COMT-Polymorphismus bei dem NS-Faktor.

Temperament and character inventory (TCI) personality profile in metamphetamine abusers: a controlled study

2004 ◽  
Vol 19 (4) ◽  
pp. 193-195 ◽  
Author(s):  
Ladislav Hosák ◽  
Marek Preiss ◽  
Martin Halíř ◽  
Eva Čermáková ◽  
Ladislav Csémy
Keyword(s):  
Healthy Volunteers ◽  
Harm Avoidance ◽  
Controlled Study ◽  
Personality Questionnaire ◽  
Novelty Seeking ◽  
Personality Profile ◽  
Temperament And Character Inventory ◽  
Prevention And Treatment ◽  
Character Inventory ◽  
Self Transcendence

AbstractWe applied the temperament and character inventory (TCI) personality questionnaire in 41 inpatients dependent on metamphetamine, and 35 controls. Novelty seeking, harm avoidance and self-transcendence were significantly higher, and persistence, self-directedness and cooperativeness were significantly lower in the patients than in the healthy volunteers. The detected differences may be important for prevention and treatment.

Correlates of Tridimensional Personality Questionnaire Scales with Selected Minnesota Multiphasic Personality Inventory Scales

1992 ◽  
Vol 71 (3_suppl) ◽  
pp. 1027-1038 ◽  
Author(s):  
Richard D. Wetzel ◽  
Stephen L. Brown ◽  
Mary Ann Knesevich ◽  
Harold A. Wolff ◽  
Charles J. Horn ◽  
...  
Keyword(s):  
Minnesota Multiphasic Personality Inventory ◽  
Harm Avoidance ◽  
Personality Questionnaire ◽  
Novelty Seeking ◽  
Factor Scores ◽  
Convenience Sample ◽  
Response Set ◽  
Reward Dependence ◽  
Dependence Scale ◽  
One Year

The pattern of correlations between selected MMPI scales and the scales of the Tridimensional Personality Questionnaire were examined in a convenience sample of 88 patients who had received both tests. Time between tests (usually less than one year) did not affect the correlations, but MMPI response-set variables ( L, F, K, F–K) did. The Tridimensional Personality Questionnaire harm avoidance scale and subscales had many correlates on the MMPI. The Novelty seeking scale and subscales showed a number of moderate correlations with a smaller number of MMPI scales; these correlations did not significantly exceed the correlations with MMPI response-set variables. The Tridimensional Personality Questionnaire reward dependence scale and subscales had few, if any, significant MMPI correlates. It was also noted that no Tridimensional Personality Questionnaire scales were related to MMPI repression factor scores.

The Tridimensional Personality Questionnaire: U.S. Normative Data

1991 ◽  
Vol 69 (3) ◽  
pp. 1047-1057 ◽  
Author(s):  
C. Robert Cloninger ◽  
Thomas R. Przybeck ◽  
Dragan M. Svrakic
Keyword(s):  
Psychometric Properties ◽  
Normative Data ◽  
Harm Avoidance ◽  
Self Report ◽  
Personality Questionnaire ◽  
Novelty Seeking ◽  
Personality Dimensions ◽  
Probability Sample ◽  
Reward Dependence ◽  
National Probability Sample

The Tridimensional Personality Questionnaire is a self-report personality inventory measuring three major personality dimensions: Novelty Seeking, Harm Avoidance, and Reward Dependence. Normative data, based on a U.S. national probability sample of 1,019 adults, are presented and the psychometric properties of the questionnaire are discussed.

The tridimensional personality questionnaire (TPQ) and depression

1998 ◽  
Vol 13 (2) ◽  
pp. 101-103 ◽  
Author(s):  
M Hansenne ◽  
W Pitchot ◽  
A Gonzalez Moreno ◽  
P-Y Machurot ◽  
M Ansseau
Keyword(s):  
State Dependence ◽  
Harm Avoidance ◽  
The Other ◽  
Healthy Controls ◽  
Personality Questionnaire ◽  
Novelty Seeking ◽  
Major Depressive ◽  
Severity Of Depression ◽  
Depressive Patients ◽  
Depressive Group

SummaryThe relationships between the Tridimensional Personality Questionnaire (TPQ) and depression were examined in a sample of 53 major depressive patients and 33 healthy controls. Depressed patients exhibit higher harm avoidance scores as well as lower novelty seeking sub-scale exploratory excitability (NSI) scores as compared to healthy controls. However, the other dimensions and their sub-scales do not differ between depressive patients and controls. In the depressive group, the harm avoidance dimension is related to the severity of depression as assessed by the Hamilton scale. This study confirms the state dependence of the harm avoidance dimension and suggests a relationship between the novelty seeking sub-scale NSI and depression.

Relationships of the Tridimensional Personality Questionnaire to Mood and Personality Measures for Depressed Patients

1994 ◽  
Vol 75 (3) ◽  
pp. 1315-1325 ◽  
Author(s):  
R. T. Mulder ◽  
P. R. Joyce
Keyword(s):  
Factor Analysis ◽  
Harm Avoidance ◽  
The Other ◽  
Personality Questionnaire ◽  
Personality Measures ◽  
Novelty Seeking ◽  
Personality Dimensions ◽  
Depressed Patients ◽  
Reward Dependence

The relationships of Tridimensional Personality Questionnaire dimensions to mood and to the Eysenck personality dimensions and Barratt's impulsivity scores are presented. Some aspects of temperament appear to be mood related, but most are not. Correlations with the other personality measures were largely as predicted. However, Exploratory Excitability correlated negatively with Harm Avoidance rather than with Novelty Seeking. Factor analysis supported this relationship. Reward Dependence was weakly represented by the other personality measures and may be tapping unique behaviours.

Personality dimensions and reactivity to 35% CO2 in panic patients and healthy controls

1994 ◽  
Vol 9 (5) ◽  
pp. 236-240 ◽  
Author(s):  
G Perna ◽  
C Arancio ◽  
A Bertani ◽  
A Gabriele ◽  
L Bellodi
Keyword(s):  
Vital Capacity ◽  
Harm Avoidance ◽  
Gas Mixture ◽  
Healthy Controls ◽  
Personality Questionnaire ◽  
Novelty Seeking ◽  
Personality Dimension ◽  
Personality Dimensions ◽  
Reward Dependence ◽  
The Relationship

SummaryThe authors investigated the relationship between personality dimensions and 35% CO2, reactivity. Fifty-one patients with PD and 26 healthy controls were assessed by the Tridimensional Personality Questionnaire and inhaled one-vital capacity of a gas mixture of 35% CO2, and 65%; 02. PD patients showed stronger reactivity to 35%. CO2, and higher scores on Harm Avoidance personality dimension. No significant relationship between reactivity to 35% CO2, and Harm Avoidance, Novelty Seeking and Reward Dependence personality dimensions were found in PD patients or controls. These results suggest that the reactivity to 35% CO2, might not be related to personality.

scholarly journals Cognitive and Affective Correlates of Temperament in Parkinson's Disease

2011 ◽  
Vol 2011 ◽  
pp. 1-8
Author(s):  
Graham Pluck ◽  
Richard G. Brown
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Affective Disorders ◽  
Harm Avoidance ◽  
Attentional Orienting ◽  
Personality Questionnaire ◽  
Novelty Seeking ◽  
Depression And Anxiety ◽  
Reaction Time Measure ◽  
And Performance

Parkinson's disease (PD) patients display low novelty seeking scores on the Tridimensional Personality Questionnaire (TPQ), which may reflect the low dopamine function that characterises the disease. People with PD also display raised harm avoidance scores. Due to these and other observations, a “parkinsonian personality” has been suggested. However, little is known about how these features relate to cognitive and affective disorders, which are also common in PD. We examined links between TPQ scores and performance on an attentional orienting task in a sample of 20 people with PD. In addition, associations between TPQ and depression and anxiety scores were explored. It was found that novelty seeking scores were significantly correlated with a reaction time measure of attentional orienting to visual novelty. Harm avoidance scores were significantly correlated with anxiety, but not depression scores. These findings extend our understanding of how temperament interacts with cognitive and affective features of the disorder.

Sign in / Sign up

Export Citation Format

Share Document