Chronic Cholezystitis Misleading as Tumor of the Gall Bladder with Concomitant Liver Abscess

Swiss Surgery ◽  
2001 ◽  
Vol 7 (1) ◽  
pp. 28-31 ◽  
Author(s):  
Teebken ◽  
Bartels ◽  
Fangmann ◽  
Nagel ◽  
Klempnauer

Ein 58jähriger Mann wurde mit Übelkeit, Oberbauchschmerzen, einem palpablen Tumor im rechten oberen Epigastrium und begleitendem Fieber aber fehlender Leukozytose und CRP-Erhöhung aufgenommen. Sowohl die Ultraschalluntersuchung als auch eine im Anschluss durchgeführte Computertomographie deuteten auf einen malignen Tumor der Gallenblase mit Infiltration der Leber und begleitender Abszessformation in den Segmenten 4b und 3 hin. Die Indikation zur Entfernung des Tumors im Sinne einer Hemihepatektomie links mit Cholezystektomie und Abszessdrainage wurde gestellt. Intraoperativ fand sich dann jedoch eine chronisch-eitrige Cholezystitis ohne Beteiligung der Leber selbst, sodass nur eine Cholezystektomie durchgeführt werden musste. Die histologische Untersuchung der Gallenblase erbrachte keinen Hinweis auf ein malignes Geschehen. Der Patient erholte sich gut von dem operativen Eingriff und konnte sieben Tage später entlassen werden. Diese Fallbeschreibung zeigt die Probleme auf, die bei der Differentialdiagnostik von entzündlichen und malignen Gallenblasenerkrankungen mit Beteiligung von angrenzenden Strukturen, insbesondere der Leber, bestehen. Trotz apparativer Untersuchungen wie Sonographie und Computertomogramm ist die letztendlich richtige Diagnose häufig nur intraoperativ zu stellen und erst dann die adäquate Therapie festlegbar. Chronische Entzündungen der Gallenblase können als solide Tumoren imponieren und dann als maligne Prozesse der Gallenblase und der angrenzenden Lebersegmente fehlinterpretiert werden.

2019 ◽  
Vol 37 (3) ◽  
pp. 22
Author(s):  
Vishwas Johri ◽  
Vimal Kumar Dhaduk ◽  
Nikunj Jain ◽  
Prasanna Kumar Reddy

2012 ◽  
Vol 21 (02) ◽  
pp. 101-104
Author(s):  
M. Kouba ◽  
S. E. Rudolph ◽  
P. Hrdlicka ◽  
M. A. Zuber

ZusammenfassungBei einem 55-jährigen Mann traten nach einem 15 Monate zurückliegenden Sturz rezidivierende Schmerzen im linken Kniegelenk auf. Klinisch fand sich eine leichte Schwellung, laborchemisch war die LDH leicht erhöht. Radiologisch zeigten sich Hinweise auf einen osteolytischen Prozess, im Knochenszintigramm zeigte sich eine Mehrspeicherung. Durch eine histologische Untersuchung konnte ein diffuses großzelliges B-Zell-Lymphom gesichert werden. Eine Kombination aus Polychemotherapie, Antikörpergabe von Rituximab und lokaler Radiatio führte zu einer Remission der Krankheitszeichen.


1924 ◽  
Vol 23 (3) ◽  
pp. 268-276 ◽  
Author(s):  
A. T. Stanton ◽  
William Flectcher ◽  
K. Kanagarayer

Two cases of fatal melioidosis are described. The first a robust Indian labourer; the second a well-nourished, muscular European.Case 1. Gradual onset. Irregular fever. Pain in the epigastrium. No physical signs of disease at first, except enlarged spleen; later, there were signs of consolidation at the bases of both lungs. Constipated at first; diarrhoea came on towards the end and the patient collapsed and died at the end of the third week.At the autopsy; there were small patches of consolidation in the lungs, composed of minute suppurating tubercles. In the liver there were similar aggregations of small suppurating tubercles and two circumscribed abscesses. The gall-bladder was thickened. The spleen was enlarged and contained septic infarcts and abscesses. In the caecum there were small superficial ulcers. B. whitmori was cultivated from the lungs, spleen, liver and gall-bladder.Animals were inoculated as follows: A guinea-pig, inoculated in the anterior nares with pus from the liver, died nine days later with caseous inflammation of the nasal passages and a caseous inguinal gland from which B. whitmori was recovered. A guinea-pig, inoculated subcutaneously with pus from the liver, died on the twenty-fifth day with abscesses in the lymphatic glands from which B. whitmori was cultivated. A guinea-pig, inoculated subcutaneously with a culture of the organism, died within sixteen hours from septicaemia. B. whitmori was recovered from the heart and spleen. A guinea-pig, inoculated subcutaneously with an attenuated culture, died on the twenty-fifth day with suppurating buboes and with abscesses in the liver and lungs from which B. whitmori was cultivated. Two horses were inoculated subcutaneously with cultures of the strain of B. whitmori cultivated from the patient. An abscess developed at the site of inoculation, in each case, but the local lesion healed and the animals have, so far, remained healthy.Case 2. The illness commenced gradually with pain after food, occasional vomiting and looseness of the bowels. The temperature became high and of the swinging type, accompanied by rigors and sweats. The liver was enlarged. The patient died on the twenty-fifth day.At the autopsy, two large abscesses were found in the liver, the gall-bladder was thickened and there were a few small superficial ulcers in the caecum. B. whitmori was cultivated from the liver abscess. No amoebae were found.The following animals were inoculated. Two wild rats were inoculated subcutaneously with a culture from this case and both died from septicaemia in less than twenty-four hours. B. whitmori was recovered from the heart's blood. The result of the subcutaneous inoculation of a guinea-pig was the same. A guinea-pig, inoculated in the nostril, died on the fifth day with a cheesy deposit in the nose and septicaemia. Another guinea-pig, inoculated in the same way, but after the organism had been subcultivated repeatedly, died on the twelfth day, with caseous tracheal glands containing B. whitmori. A rabbit, inoculated subcutaneously, died in twenty-six hours from septicaemia with tubereles in the peritoneum. B. whitmori was cultivated from the peritoneum and from the heart's blood. A monkey fed on a culture remained healthy. A pony inoculated intravenously recovered after a week's fever.


1964 ◽  
Vol 47 (1) ◽  
pp. 82-84 ◽  
Author(s):  
G.B. Robson ◽  
L. Frederick Fenster

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