Gall Bladder Perforation Leads to Liver Abscess Formation ? Role of Ultrasonography

2015 ◽  
Vol 05 (03) ◽  
Author(s):  
Rikki Singal Rajinder Pal
Keyword(s):  
Gall Bladder ◽  
Liver Abscess ◽  
Abscess Formation ◽  
Bladder Perforation

scholarly journals Role of T Lymphocytes in Liver Abscess Formation by Bacteroides fragilis in Mice

2011 ◽  
Vol 79 (6) ◽  
pp. 2234-2240 ◽  
Author(s):  
Doo Ryeon Chung ◽  
Hye-Rim Park ◽  
Chung-Gyu Park ◽  
Eung-Soo Hwang ◽  
Chang-Yong Cha
Keyword(s):  
T Cells ◽  
T Cell ◽  
Liver Abscess ◽  
Bacteroides Fragilis ◽  
Cell Receptor ◽  
Abscess Formation ◽  
Wild Type ◽  
Content Type ◽  
In The Wild

ABSTRACTThe underlying mechanisms of liver abscess formation have not been fully elucidated with regard to the interaction between bacterial virulence factors and the immune response. The objective of this study was to determine the role of the host T cells in liver abscess formation caused byBacteroides fragilis. We developed a liver abscess mouse model with inoculation ofB. fragilisthrough the hepatic portal vein and examined the role of T cells by studying T cell-deficient mice, as well as conducting adoptive T cell transfer experiments. No microabscess was formed in the αβ T cell receptor-positive (αβTCR+) T cell-depleted mice, in contrast to the results for the control mice. In addition, the αβTCR knockout (KO) mice showed significantly lower numbers of microabscesses, and the abscesses were smaller in size than those in the wild-type mice. Adoptive transfer of T cells purified from the wild-type mice into the αβTCR KO mice resulted in liver abscess formation in those mice. These findings suggest that T cells play an essential role in liver abscess formation caused byB. fragilisin mice.

Role of Prostaglandin E2 on Amoebic Liver Abscess Formation in Hamsters

1997 ◽  
Vol 53 (6) ◽  
pp. 411-421 ◽  
Author(s):  
B Sánchez-Ramírez ◽  
B Escalante ◽  
J.L Rosales-Encina ◽  
P Talamás-Rohana
Keyword(s):  
Prostaglandin E2 ◽  
Liver Abscess ◽  
Abscess Formation ◽  
Amoebic Liver Abscess

Chronic Cholezystitis Misleading as Tumor of the Gall Bladder with Concomitant Liver Abscess

Swiss Surgery ◽  
2001 ◽  
Vol 7 (1) ◽  
pp. 28-31 ◽  
Author(s):  
Teebken ◽  
Bartels ◽  
Fangmann ◽  
Nagel ◽  
Klempnauer
Keyword(s):  
Gall Bladder ◽  
Liver Abscess ◽  
Solide Tumoren ◽  
Fand Sich ◽  
Histologische Untersuchung ◽  
Chronische Entzündungen

Ein 58jähriger Mann wurde mit Übelkeit, Oberbauchschmerzen, einem palpablen Tumor im rechten oberen Epigastrium und begleitendem Fieber aber fehlender Leukozytose und CRP-Erhöhung aufgenommen. Sowohl die Ultraschalluntersuchung als auch eine im Anschluss durchgeführte Computertomographie deuteten auf einen malignen Tumor der Gallenblase mit Infiltration der Leber und begleitender Abszessformation in den Segmenten 4b und 3 hin. Die Indikation zur Entfernung des Tumors im Sinne einer Hemihepatektomie links mit Cholezystektomie und Abszessdrainage wurde gestellt. Intraoperativ fand sich dann jedoch eine chronisch-eitrige Cholezystitis ohne Beteiligung der Leber selbst, sodass nur eine Cholezystektomie durchgeführt werden musste. Die histologische Untersuchung der Gallenblase erbrachte keinen Hinweis auf ein malignes Geschehen. Der Patient erholte sich gut von dem operativen Eingriff und konnte sieben Tage später entlassen werden. Diese Fallbeschreibung zeigt die Probleme auf, die bei der Differentialdiagnostik von entzündlichen und malignen Gallenblasenerkrankungen mit Beteiligung von angrenzenden Strukturen, insbesondere der Leber, bestehen. Trotz apparativer Untersuchungen wie Sonographie und Computertomogramm ist die letztendlich richtige Diagnose häufig nur intraoperativ zu stellen und erst dann die adäquate Therapie festlegbar. Chronische Entzündungen der Gallenblase können als solide Tumoren imponieren und dann als maligne Prozesse der Gallenblase und der angrenzenden Lebersegmente fehlinterpretiert werden.

scholarly journals Role of MSCT in the diagnosis of perforated gall bladder (a retrospective study)

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Mohamed M. Harraz ◽  
Ahmed H. Abouissa
Keyword(s):  
Computed Tomography ◽  
Retrospective Study ◽  
Gall Bladder ◽  
Acute Cholecystitis ◽  
Acute Diverticulitis ◽  
Wall Thickening ◽  
Free Fluid ◽  
Iodinated Contrast ◽  
Contrast Enhanced

Abstract Background Although gall bladder perforation (GBP) is not common, it is considered a life-threating condition, and the possibility of occurrence in cases of acute cholecystitis must be considered. The aim of this study was to assess the role of multi-slice computed tomography (MSCT) in the assessment of GBP. Results It is a retrospective study including 19 patients that had GBP out of 147, there were 11 females (57.8%) and 8 males (42.1%), aged 42 to 79 year (mean age 60) presented with acute abdomen or acute cholecystitis. All patients were examined with abdominal ultrasonography and contrast-enhanced abdominal MSCT after written informed consent was obtained from the patients. This study was between January and December 2018. Patients with contraindications to contrast-enhanced computed tomography (CT) (pregnancy, acute kidney failure, or allergy to iodinated contrast agents) who underwent US only were excluded. Patients with other diagnoses, such as acute diverticulitis of the right-sided colon or acute appendicitis, were excluded. The radiological findings were evaluated such as GB distention; stones; wall thickening, enhancement, and defect; pericholecystic free fluid or collection; enhancement of liver parenchyma; and air in the wall or lumen. All CT findings are compared with the surgical results. Our results revealed that the most important and diagnostic MSCT finding in GBP is a mural defect. Nineteen patients were proved surgically to have GBP. Conclusion GBP is a rare but very serious condition and should be diagnosed and treated as soon as possible to decrease morbidity and mortality. The most accurate diagnostic tool is the CT, MSCT findings most specific and sensitive for the detection of GBP and its complications.

scholarly journals Significance and Impact of the Intersphincteric Plane Sepsis in the Management of the Perianal Sepsis: Ultrasound Study

2021 ◽  
Author(s):  
Ashraf Talaat Youssef
Keyword(s):  
Digital Rectal Examination ◽  
Perianal Fistula ◽  
Final Diagnosis ◽  
Abscess Formation ◽  
Study Group ◽  
Potential Space ◽  
Anal Glands ◽  
Ultrasound Study ◽  
Perianal Sepsis

Abstract Background The intersphincteric plane (ISP) is a potential space between the external and the internal anal sphincters. About 90% of the perianal sepsis is caused by an obstruction of the ducts of anal glands with subsequent secondary bacterial infection. The imaging modalities used to diagnose perianal sepsis are the ultrasound via endoanal and transperineal routes and magnetic resonance imaging. Objective  The study aimed to identify the various patterns of the ISP sepsis and their incidence among our study group and to clarify the significance of ISP in the pathogenesis of anorectal abscesses and various types of perianal fistula tracts, to optimize the surgical management. Methods Retrospective descriptive study in which 57 patients with an ISP sepsis were evaluated with full medical history, clinical exam, and ultrasound; the final diagnosis was based on combining the results of ultrasound, digital rectal examination under anesthesia, and the operative results. Results The current study showed many patterns of the ISP sepsis and estimated the incidence of each pattern among our study group; such patterns could be fistula tracts, sinus tracts, abscesses, intersphincteric abscess with supralevator extension, sinus with abscess formation, fistula with abscess formation, distension of the ISP with free pus, and other complex patterns like horse abscess, abscess with transsphincteric sinus, and ISP fistula/sinus with transsphincteric branches. Conclusion Understanding the role of the ISP in the pathogenesis of anorectal abscesses and perianal fistula tracts can help in reaching the optimum way of management.

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