Genetic polymorphisms of the apolipoprotein A-IV in a Greek population and their relation to plasma lipid and lipoprotein levels

2002 ◽  
Vol 62 (3) ◽  
pp. 208-213 ◽  
Author(s):  
G Miltiadous ◽  
M Hatzivassiliou ◽  
E Bashiardes ◽  
E Bairaktari ◽  
MA Cariolou ◽  
...  
Keyword(s):  
Genetic Polymorphisms ◽  
Plasma Lipid ◽  
Greek Population ◽  
Apolipoprotein A

Genetic polymorphisms of drug-metabolizing enzymes CYP2D6, CYP2C9, CYP2C19 and CYP3A5 in the Greek population

2007 ◽  
Vol 21 (4) ◽  
pp. 419-426 ◽  
Author(s):  
Kostas Arvanitidis ◽  
Georgia Ragia ◽  
Maria Iordanidou ◽  
Sofia Kyriaki ◽  
Athanasia Xanthi ◽  
...  
Keyword(s):  
Genetic Polymorphisms ◽  
Greek Population ◽  
Drug Metabolizing Enzymes ◽  
Metabolizing Enzymes

Genetic polymorphisms associated with the prevalence of retinal vein occlusion in a Greek population

2019 ◽  
Vol 39 (11) ◽  
pp. 2637-2648 ◽  
Author(s):  
Aikaterini Christodoulou ◽  
Eleni Bagli ◽  
Maria Gazouli ◽  
Marilita M. Moschos ◽  
Georgios Kitsos
Keyword(s):  
Retinal Vein Occlusion ◽  
Genetic Polymorphisms ◽  
Greek Population ◽  
Vein Occlusion

scholarly journals Structure−Function Studies of Human Apolipoprotein A-V:  A Regulator of Plasma Lipid Homeostasis†

Biochemistry ◽  
2003 ◽  
Vol 42 (31) ◽  
pp. 9416-9423 ◽  
Author(s):  
Jennifer A. Beckstead ◽  
Michael N. Oda ◽  
Dale D. O. Martin ◽  
Trudy M. Forte ◽  
John K. Bielicki ◽  
...  
Keyword(s):  
Structure Function ◽  
Plasma Lipid ◽  
Lipid Homeostasis ◽  
Human Apolipoprotein ◽  
Apolipoprotein A

Genetic polymorphisms and risk of MALT lymphoma in Greek population

2022 ◽  
Vol 70 (2) ◽  
pp. 103330
Author(s):  
A. Velissari ◽  
T.P Vassilakopoulos ◽  
M.K Angelopoulou ◽  
P Korkolopoulou ◽  
G. Bamias ◽  
...  
Keyword(s):  
Genetic Polymorphisms ◽  
Malt Lymphoma ◽  
Greek Population

4.P.158 Effect of the apolipoprotein A-IV 360 (Gln/HIS) polymorphism on plasma lipid response to dietary fat

1997 ◽  
Vol 134 (1-2) ◽  
pp. 329
Author(s):  
S. Jansen ◽  
J. López-Miranda ◽  
J.M. Ordovas ◽  
A. Blanco ◽  
M. Ostos ◽  
...  
Keyword(s):  
Dietary Fat ◽  
Plasma Lipid ◽  
Apolipoprotein A ◽  
Lipid Response

scholarly journals Apolipoprotein A-IV polymorphism and its effect on plasma lipid and apolipoprotein concentrations.

1988 ◽  
Vol 29 (12) ◽  
pp. 1621-1627 ◽  
Author(s):  
P de Knijff ◽  
M Rosseneu ◽  
U Beisiegel ◽  
W de Keersgieter ◽  
R R Frants ◽  
...  
Keyword(s):  
Plasma Lipid ◽  
Apolipoprotein A

scholarly journals Apolipoprotein A-IV regulates chylomicron metabolism–mechanism and function

2012 ◽  
Vol 302 (6) ◽  
pp. G628-G636 ◽  
Author(s):  
Alison B. Kohan ◽  
Fei Wang ◽  
Xiaoming Li ◽  
Suzanne Bradshaw ◽  
Qing Yang ◽  
...  
Keyword(s):  
Dietary Fat ◽  
Cholesterol Metabolism ◽  
Plasma Lipid ◽  
Physiological Role ◽  
Lipid Absorption ◽  
Fat Absorption ◽  
Apolipoprotein A ◽  
And Function ◽  
Dietary Fat Absorption

Dietary fat is an important mediator of atherosclerosis and obesity. Despite its importance in mediating metabolic disease, there is still much unknown about dietary fat absorption in the intestine and especially the detailed biological roles of intestinal apolipoproteins involved in that process. We were specifically interested in determining the physiological role of the intestinal apolipoprotein A-IV (A-IV) using A-IV knockout (KO) mice. A-IV is stimulated by fat absorption in the intestine and is secreted on nascent chylomicrons into intestinal lymph. We found that A-IV KO mice had reduced plasma triglyceride (TG) and cholesterol levels and that this hypolipidemia persisted on a high-fat diet. A-IV KO did not cause abnormal intestinal lipid absorption, food intake, or adiposity. Additionally, A-IV KO did not cause abnormal liver TG and cholesterol metabolism, as assessed by measuring hepatic lipid content, lipogenic and cholesterol synthetic gene expression, and in vivo VLDL secretion. Instead, A-IV KO resulted in the secretion of larger chylomicrons from the intestine into the lymph, and those chylomicrons were cleared from the plasma more slowly than wild-type chylomicrons. These data suggest that A-IV has a previously unknown role in mediating the metabolism of chylomicrons, and therefore may be important in regulating plasma lipid metabolism.

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