scholarly journals Major life events and major chronic difficulties are differentially associated with history of major depressive episodes.

2007 ◽  
Vol 116 (1) ◽  
pp. 116-124 ◽  
Author(s):  
Scott M. Monroe ◽  
George M. Slavich ◽  
Leandro D. Torres ◽  
Ian H. Gotlib
2002 ◽  
Vol 16 (4) ◽  
pp. 405-419 ◽  
Author(s):  
Jelena Spasojević ◽  
Lauren B. Alloy

Developmental antecedents of ruminative response style were examined in 137 college freshmen, who were followed prospectively for 2.5 years. Reports of mothers’ and fathers’ psychologically overcontrolling parenting as well as a history of childhood sexual (for women only) and emotional maltreatment were all related to ruminative response style. In addition, ruminative response style mediated the relationships between these developmental factors and the number of major depressive episodes experienced by participants during the follow-up period. Potential explanations and important implications of these findings are discussed.


2008 ◽  
Vol 33 (1) ◽  
pp. 50-58 ◽  
Author(s):  
John R. Z. Abela ◽  
Randy P. Auerbach ◽  
Sabina Sarin ◽  
Zia Lakdawalla

2016 ◽  
Vol 5 (1) ◽  
pp. 174-181 ◽  
Author(s):  
Joelle LeMoult ◽  
Katharina Kircanski ◽  
Gautam Prasad ◽  
Ian H. Gotlib

Most individuals who develop major depressive disorder (MDD) will experience a recurrent depressive episode; we know little, however, about cognitive mechanisms that increase the likelihood of recurrence. In the current study we examined whether negatively biased self-referential processing, negative life events, baseline depressive symptoms, and psychotropic medication use predicted the onset of a subsequent depressive episode in a longitudinal study of women with a history of recurrent MDD. Higher levels of depressive symptoms at baseline predicted experiencing a greater number of negative life events, which, in turn, tended to predict recurrence of depression. It is important that after accounting for other associations, negatively biased self-referential processing contributed unique variance to the likelihood of experiencing a depressive episode over the next 3 years. Thus, negatively biased self-referential processing appears to be a significant risk factor for the recurrence of depressive episodes and may be an important target for interventions aimed at preventing future episodes.


2006 ◽  
Vol 36 (6) ◽  
pp. 789-795 ◽  
Author(s):  
JOHN M. HETTEMA ◽  
JONATHAN W. KUHN ◽  
CAROL A. PRESCOTT ◽  
KENNETH S. KENDLER

Background. Both generalized anxiety disorder (GAD) and stressful life events (SLEs) are established risk factors for major depressive disorder, but no studies exist that examine the interrelationship of their impact on depressive onsets. In this study, we sought to analyze the joint effects of prior history of GAD and recent SLEs on risk for major depressive episodes, comparing these in men and women.Method. In a population-based sample of 8068 adult twins, Cox proportional hazard models were used to predict onsets of major depression from reported prior GAD and last-year SLEs rated on long-term contextual threat.Results. For all levels of threat, prior GAD increases risk for depression, with a monotonic relationship between threat level and risk. While females without prior GAD consistently show higher depressive risk than males, this is no longer the case in subjects with prior GAD who have experienced SLEs. Rather, males appear to be more vulnerable to the depressogenic effects of both prior GAD and SLEs.Conclusion. The effects of prior GAD and SLEs jointly increase the risk of depression in both sexes, but disproportionately so in males.


2000 ◽  
Vol 177 (4) ◽  
pp. 331-335 ◽  
Author(s):  
Toshiaki A. Furukawa ◽  
Toshinori Kitamura ◽  
Kiyohisa Takahashi

BackgroundGeneralisability of existing studies on the naturalistic history of major depression is undermined by overrepresentation of in-patients and tertiary care academic centres, inclusion of patients already on treatment and/or incomplete follow-up.AimsTo report the time to recovery of an inception cohort of unipolar major depressive episodes.MethodA multi-centre prospective follow-up study of patients with a mood disorder, who had been selected to be representative of the untreated first-visit patients at 23 psychiatric settings from all over Japan.ResultsThe median time to recovery of the index episode after treatment commencement was 3 months (95% CI 2.5–3.6): 26% of the cohort reached asymptomatic or minimally symptomatic status by I month, 63% by 3 months, 85% by 12 months and 88% by 24 months.ConclusionsOur estimate of the episode length was 25–50% shorter than estimates reported in the literature.


2009 ◽  
Vol 40 (3) ◽  
pp. 441-449 ◽  
Author(s):  
L. D. Torres ◽  
A. Z. Barrera ◽  
K. Delucchi ◽  
C. Penilla ◽  
E. J. Pérez-Stable ◽  
...  

BackgroundLimited evidence has suggested that quitting smoking increases the incidence of major depressive episodes (MDEs), particularly for smokers with a history of depression. Further evidence for this increase would have important implications for guiding smoking cessation.MethodSpanish- and English-speaking smokers without a current MDE (n=3056) from an international, online smoking cessation trial were assessed for abstinence 1 month after their initial quit date and followed for a total of 12 months. Incidence of screened MDE was examined as a function of abstinence and depression history.ResultsContinued smoking, not abstinence, predicted MDE screened at 1 month [smoking 11.5% v. abstinence 7.8%, odds ratio (OR) 1.36, 95% confidence interval (CI) 1.04–1.78, p=0.02] but not afterwards (smoking 11.1% v. abstinence 9.8%, OR 1.05, 95% CI 0.77–1.45, p=0.74). Depression history predicted MDE screened at 1 month (history 17.1% v. no history 8.6%, OR 1.71, 95% CI 1.29–2.27, p<0.001) and afterwards (history 21.7% v. no history 8.3%, OR 3.87, 95% CI 2.25–6.65, p<0.001), although the interaction between history and abstinence did not.ConclusionsQuitting smoking was not associated with increased MDE, even for smokers with a history of depression, although a history of depression was. Instead, not quitting was associated with increased MDE shortly following a quit attempt. Results from this online, large, international sample of smokers converge with similar findings from smaller, clinic-based samples, suggesting that in general, quitting smoking does not increase the incidence of MDEs.


2011 ◽  
Vol 199 (1) ◽  
pp. 3-4 ◽  
Author(s):  
Allan H. Young ◽  
Holly MacPherson

SummaryMajor depressive episodes are common in bipolar disorder, which consequently may be misdiagnosed as major depressive disorder. Improved detection of bipolar disorder rests upon better ascertainment of a history of hypomania. Antidepressants are of dubious benefit in bipolar disorder and more accurate diagnosis of depression would promote better treatment.


1994 ◽  
Vol 164 (3) ◽  
pp. 342-348 ◽  
Author(s):  
Kathleen Ries Merikangas ◽  
Werner Wicki ◽  
Jules Angst

This paper describes the application of prospective longitudinal data from an epidemiological sample of young adults to define subtypes of major depression. Depression was classified on a spectrum from subthreshold manifestation of symptoms and duration at one end, to cases with recurrent episodes of depression meeting duration criteria for major depressive episodes at the other. There was a direct relationship between the severity of depression over the longitudinal course and both duration and recurrence of depressive episodes. The subgroup of depression with recurrence of both brief and longer duration episodes could be discriminated on most of the indicators of validity including symptoms, impairment, family history, and suicide attempts. In light of the young age of this cohort, the strong history of suicide attempts and other complications of depression among the subjects with recurrent depression was striking. These findings underscore the importance of employing course as a classification criterion of depression, and the inclusion of subthreshold episodes of depression in the characterisation of course.


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